9月
Crizotinib acetate；化合物 T1661LPF02341066|||PF-2341066|||PF 02341066|||PF-02341066|||PF2341066；PF02341 (2024/9/1)
简介：crizotinib, an orally bioavailable agent, belongs to the class of c-met/hepatocyte growth factor receptor (hgfr) tyrosine kinase inhibitors with potential antineoplastic activity.
Propargyl-PEG4-Br；化合物 T16619Propargyl-PEG4-Br (2024/9/1)
简介：propargyl-peg4-br is a non-cleavable adc linker used in the synthesis of antibody-drug conjugates (adcs)[1].
Propargyl-PEG4-Boc；化合物 T16618Propargyl-PEG4-Boc (2024/9/1)
简介：propargyl-peg4-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG4-beta-D-glucose；化合物 T16617Propargyl-PEG4-beta-D-glucose (2024/9/1)
简介：propargyl-peg4-beta-d-glucose is a polyethylene glycol (peg) derivatized protac linker employed in the preparation of proteolysis targeting chimeras (protacs)[1].
Propargyl-PEG4-amine；化合物 T16616Propargyl-PEG4-amine (2024/9/1)
简介：propargyl-peg4-amine is a peg-based protac linker can be used in the synthesis of protacs.
Propargyl-PEG4-alcohol；化合物 T16615Propargyl-PEG4-alcohol (2024/9/1)
简介：propargyl-peg4-alcohol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG4-acid；化合物 T16614Propargyl-PEG4-acid (2024/9/1)
简介：propargyl-peg4-acid is a peg-based protac linker can be used in the synthesis of btk-iap protacs ibrutinib -based protac 2 and an analogue protac 3. protac 3 causes btk degradation with a dc50 of 200 nm in thp-1 cells[1].
Propargyl-PEG4-5-nitrophenyl carbonate；化合物 T16613Propargyl-PEG4-5-nitrophenyl carbonate (2024/9/1)
简介：propargyl-peg4-5-nitrophenyl carbonate is a polyethylene glycol (peg) derivative specifically designed as a linker for proteolysis targeting chimeras (protacs) synthesis[1].
Propargyl-PEG3-OCH2-Boc；化合物 T16610Propargyl-PEG3-OCH2-Boc (2024/9/1)
简介：propargyl-peg3-och2-boc is a polyethylene glycol (peg)-derived linker designed for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Crizotinib克唑替尼PF-02341066|||克唑替尼 (2024/9/1)
简介：crizotinib (pf-02341066) is a small molecule tyrosine kinase inhibitor that inhibits c-met and alk receptors (ic50=8/20 nm), is atp-competitive, and also inhibits ros1. crizotinib exhibits antitumor activity and inhibits tumor growth.
Propargyl-PEG3-CH2COOH；化合物 T16609Propargyl-PEG3-CH2COOH (2024/9/1)
简介：propargyl-peg3-ch2cooh is a peg-based protac linker can be used in the synthesis of protacs[1].
Propargyl-PEG3-bromide；化合物 T16608Propargyl-PEG3-bromide (2024/9/1)
简介：propargyl-peg3-bromide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG3-Boc；化合物 T16607Propargyl-PEG3-Boc (2024/9/1)
简介：propargyl-peg3-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG3-alcohol；化合物 T16606Propargyl-PEG3-alcohol (2024/9/1)
简介：propargyl-peg3-alcohol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG3-acid丙炔基-二聚乙二醇-羧酸丙炔基-二聚乙二醇-羧酸 (2024/9/1)
简介：propargyl-peg3-acid is a non-cleavable (3-unit peg) adc linker. propargyl-peg3-acid is also a peg-based protac linker used to synthesize 6-ohda-peg3-yne. 6-ohda-peg3-yne contains 6-ohda and propargyl-peg3-acid[1].
Propargyl-PEG2-Tos；化合物 T16604Propargyl-PEG2-Tos (2024/9/1)
简介：propargyl-peg2-tos is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG2-OH；化合物 T16603Propargyl-PEG2-OH (2024/9/1)
简介：propargyl-peg2-oh is a polyethylene glycol (peg)-based protac linker, specifically designed for efficient synthesis of thalidomide-o-peg2-propargyl.
Propargyl-PEG2-NHBoc；化合物 T16602Propargyl-PEG2-NHBoc (2024/9/1)
简介：propargyl-peg2-nhboc is a cleavable adc linker utilized for the synthesis of antibody-drug conjugates (adcs). this peg-based protac linker, namely propargyl-peg2-nhboc, holds potential for the synthesis of protacs[1].
Propargyl-PEG2-N-bis(PEG2)；化合物 T16601Propargyl-PEG2-N-bis(PEG2) (2024/9/1)
简介：propargyl-peg2-n-bis(peg2) is a polyethylene glycol (peg)-based linker compound, employed for the synthesis of protacs (proteolysis-targeting chimeras).
Propargyl-PEG2-Ms；化合物 T16600Propargyl-PEG2-Ms (2024/9/1)
简介：propargyl-peg2-ms is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Silibinin；水飞蓟宾 ASilibinin A|||Silybin|||Silymarin I；水飞蓟宾 A|||水飞蓟宾|||Silibinin A|||Silybin|||Silymari (2024/9/1)
简介：silibinin (silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin and others. silibinin itself is a mixture of two diastereomers, silybin a and silybin b, in approximately equimolar ratio. both in vitro and animal research suggest that silibinin has hepatoprotective (antihepatotoxic) properties that protect liver cells against toxins. silibinin h
Propargyl-PEG3-NHS ester；化合物 T16599Propargyl-PEG3-NHS ester (2024/9/1)
简介：propargyl-peg3-nhs ester is a cleavable adc linker used in the synthesis of antibody-drug conjugates (adcs)[1].
Propargyl-PEG2-amine2-(2-(丙-2-炔-1-基氧基)乙氧基)乙胺2-(2-(丙-2-炔-1-基氧基)乙氧基)乙胺 (2024/9/1)
简介：propargyl-peg2-amine is a non-cleavable adc linker employed for synthesizing antibody-drug conjugates (adcs). it is a peg-based protac linker that finds applications in protac synthesis [1][2].
Propargyl-PEG2-acid；化合物 T16597Propargyl-PEG2-acid (2024/9/1)
简介：propargyl-peg2-acid is a non-cleavable 2 unit peg adc linker used in the synthesis of antibody-drug conjugates (adcs)[1].
Propargyl-PEG12-OH；化合物 T16596Propargyl-PEG12-OH (2024/9/1)
简介：propargyl-peg12-oh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG10-Boc；化合物 T16595Propargyl-PEG10-Boc (2024/9/1)
简介：propargyl-peg10-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG10-amine；化合物 T16594Propargyl-PEG10-amine (2024/9/1)
简介：propargyl-peg10-amine is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG10-acid；化合物 T16593Propargyl-PEG10-acid (2024/9/1)
简介：propargyl-peg10-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Propargyl-PEG1-SS-PEG1-propargyl；化合物 T16592Propargyl-PEG1-SS-PEG1-propargyl (2024/9/1)
简介：propargyl-peg1-ss-peg1-propargyl refers to a cleavable di-functional polyethylene glycol (peg) linker composed of two units. this specific linker is employed in the synthesis of antibody-drug conjugates (adcs), where it plays a critical role in linking the antibody to the drug. [1]
Propargyl-PEG1-SS-PEG1-PFP ester；化合物 T16591Propargyl-PEG1-SS-PEG1-PFP ester (2024/9/1)
简介：propargyl-peg1-ss-peg1-pfp ester is a cleavable linker consisting of a 1-unit polyethylene glycol (peg) backbone, designed for use in the synthesis of antibody-drug conjugates (adcs)[1].
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