9月
Gestodene；孕二烯酮SHB 331|||WL 70；SHB 331|||WL 70|||孕二烯酮 (2024/9/1)
简介：gestodene (wl 70) is a progestogen hormonal contraceptive.
CCR1 antagonist 8；化合物 T14899CCR1 antagonist 8 (2024/9/1)
简介：ccr1 antagonist 8, a third azaindazole series compound, is a ccr1 antagonist (ic50: 1.8 nm in ca2+ flux assay).
CCG-63808；化合物CCG-63808CCG-63808 (2024/9/1)
简介：ccg-63808 is a reversible inhibitor of regulator of g-protein signaling (rgs) proteins. ccg-63808 dose-dependently inhibits the tr-fret signal between rgs4-af488 and tb-gαo with ic50 values of 1.9 μm.
CCG-63802；化合物CCG-63802CCG-63802 (2024/9/1)
简介：ccg-63802 is a reversible small-molecule inhibitor of regulator of g protein signaling (rgs) proteins. ccg-63802 inhibits the interaction between rgs4 and galpha with an ic50 value of 1.4 μm.
CC0651；化合物 T14896CC0651 (2024/9/1)
简介：cc0651 is an allosteric inhibitor of the human cdc34 ubiquitin-conjugating enzyme. cc0651 potently inhibits the ubiquitination of p27kip1 (ic50: 1.72 μm).
Tanzisertib；化合物TanzisertibCC-930；CC-930 (2024/9/1)
简介：tanzisertib (cc-930) (cc-930) is a potent inhibitor of jnk1/2/3 with ic50s of 61/7/6 nm, respectively, with potential antifibrotic activity.
CC-90003；化合物CC-90003CC-90003 (2024/9/1)
简介：cc-90003 is a selective inhibitor of erk 1/2. it has antitumor activity.
CC-885；化合物CC-885CC-885 (2024/9/1)
简介：cc-885 is a modulator of cereblon (crbn). it has potent anti-tumour activity.
Cbz-NH-PEG8-C2-acid；化合物 T14892Cbz-NH-PEG8-C2-acid (2024/9/1)
简介：cbz-nh-peg8-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Cbz-NH-PEG6-C2-acid；化合物 T14891Cbz-NH-PEG6-C2-acid (2024/9/1)
简介：cbz-nh-peg6-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Cbz-NH-PEG5-C2-acid；化合物 T14890Cbz-NH-PEG5-C2-acid (2024/9/1)
简介：cbz-nh-peg5-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Fosinopril sodium；福辛普利钠SQ28555；SQ28555|||福辛普利钠 (2024/9/1)
简介：fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. it is a prodrug that is converted to its active metabolite fosinoprilat.
Cbz-NH-PEG4-C2-acid；化合物 T14889Cbz-NH-PEG4-C2-acid (2024/9/1)
简介：cbz-nh-peg4-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Cbz-NH-PEG3-C2-acid；化合物 T14888Cbz-NH-PEG3-C2-acid (2024/9/1)
简介：cbz-nh-peg3-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Cbz-NH-PEG2-C2-acid；化合物 T14887Cbz-NH-PEG2-C2-acid (2024/9/1)
简介：cbz-nh-peg2-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Cbz-B3A；化合物 Cbz-B3ACbz-B3A (2024/9/1)
简介：cbz-b3a is a potent inhibitor of mtorc1 signalling, inhibits phosphorylation of eif4e-binding protein 1 (4ebp1) and blocks translation by 68%.
CBS9106；化合物 CBS9106Felezonexor|||SL-801；Felezonexor|||SL-801 (2024/9/1)
简介：cbs9106 (sl-801) is a reversible oral crm1 inhibitor with crm1 degrading and antitumor activity.cbs9106 inhibits crm1-dependent nuclear export and reduces crm1 protein levels.cbs9106 inhibits tumor growth and prolongs the survival of mice bearing tumor xenografts.cbs9106 is an inhibitor of crm1-dependent nuclear export and reduces crm1 protein levels.
CBR-5884；化合物CBR-5884CBR-5884 (2024/9/1)
简介：cbr-5884 is an selective, active of phosphoglycerate dehydrogenase (phgdh) inhibitor with an ic50 of 33 μm. cbr-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. cbr-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis. biochemical characterization of the inhibitor revealed that it was a noncompetitive inhibitor that showed a time
Idoxifene；化合物 T14883CB7432；CB7432 (2024/9/1)
简介：idoxifene is a tissue-specific selective estrogen receptor modulator.
CB30865；化合物 T14882ZM 242421；ZM 242421 (2024/9/1)
简介：cb30865 is a potent inhibitor of nampt, an enzyme present in the nad biosynthetic pathway.
CB1 antagonist 2；化合物CB1 antagonist 2AM4113；AM4113 (2024/9/1)
简介：cb1 antagonist 2 (am4113) is caimabinoid 1 (cb1) antagonist which inhibits cb1 in vivo with an ic50 of 25.5 nm.
CB-7921220；化合物CB-79212206-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid|||6-(4-Aminostyryl)pico (2024/9/1)
简介：cb-7921220 (6-[2-(4-aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.
Procarbazine hydrochloride；盐酸甲基苄肼NSC-77213 HCl|||Procarbazine HCl；NSC-77213 HCl|||盐酸甲基苄肼|||Procarbaz (2024/9/1)
简介：procarbazine hydrochloride (nsc-77213 hcl) is the hydrochloride salt of a methylhydrazine derivative with antineoplastic and mutagenic activities. although the exact mode of cytotoxicity has not been elucidated, procarbazine, after metabolic activation, appears to inhibit the trans-methylation of methionine into transfer rna (t-rna), thereby preventing protein synthesis and consequently dna and rna synthesis. this agent may also undergo auto-oxidation, resulting in the formation of cytotoxic fre
CB 300919；化合物 T14879CB 300919 (2024/9/1)
简介：cb 300919 is a quinazoline-based antitumor agent with high activity in the ch1 human ovarian tumor xenograft and has continuous exposure (96 h) growth inhibition (ic50: 2 nm).
CAY10566；化合物CAY10566CAY10566 (2024/9/1)
简介：cay10566 shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-coas (lcfa-coas) to monounsaturated lcfa-coas in hepg2 cells (ic50=7.9 nm or 6.8 nm). cay10566 is a potent, orally bioavailable and selective stearoyl-coa desaturase1 (scd1) inhibitor with ic50s of 4.5 and 26 nm in mouse and human enzymatic assays, respectively..
Cauloside C；葳岩仙皂苷 CCauloside C (2024/9/1)
简介：cauloside c, a triterpene glycoside isolated from caulophyllum robustum max, exerts anti-inflammatory effects through the inhibition of expression of inos and proinflammatory cytokines.
Carotegrast化合物 T14876Carotegrast (2024/9/1)
简介：carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.
Indocyanine green吲哚菁绿Cardiogreen|||IC Green|||Foxgreen|||吲哚菁绿 (2024/9/1)
简介：indocyanine green (cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.
Carboxyrhodamine 110-PEG4-alkyne；化合物 T14874Carboxyrhodamine 110-PEG4-alkyne (2024/9/1)
简介：carboxyrhodamine 110-peg4-alkyne is a polyethylene glycol (peg) derived linker used for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Carboxyrhodamine 110-PEG3-Azide；化合物 T14873Carboxyrhodamine 110-PEG3-Azide (2024/9/1)
简介：carboxyrhodamine 110-peg3-azide is a polyethylene glycol (peg)-based linker used for the synthesis of proteolysis targeting chimeras (protacs) [1].
MSN交谈
