Carboxyamidotriazole;化合物 T14872CAI|||L-651582;CAI|||L-651582 (2024/9/1)
简介:carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. it shows anti-inflammatory, anti-tumor, and antiangiogenic effects.
Carboxyamidotriazole Orotate;化合物Carboxyamidotriazole OrotateL-651582 Orotate|||CAI Orotate;L-651582 (2024/9/1)
简介:carboxyamidotriazole orotate (l-651582 orotate) is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways. carboxyamidotriazole orotate (l-651582 orotate) is the orotate salt form of carboxyamidotriazole (cai), an orally bioavailable signal transduction inhibitor that in vitro has been shown to possess antileukaemic activities. carboxyamidotriazole orotate shows anti-tumor, anti-inflammatory, and antiangiogenic effects.
Carboxy-PEG5-sulfonic acid;化合物 T14870Carboxy-PEG5-sulfonic acid (2024/9/1)
简介:carboxy-peg5-sulfonic acid, a peg-based protac linker, is utilized for the synthesis of protacs[1].
Fluvastatin sodium;氟伐他汀钠XU 62320 sodium|||XU-62-320|||Fluvastatin sodium salt;XU 62320 sodium|||XU-6 (2024/9/1)
简介:fluvastatin sodium (fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme a reductase (hmgcr), is a commonly used cholesterol lowering agent.
Carboxy-PEG4-sulfonic acid;化合物 T14869Carboxy-PEG4-sulfonic acid (2024/9/1)
简介:carboxy-peg4-sulfonic acid is a peg-based linker commonly employed in protac synthesis [1].
Carboxy-PEG2-sulfonic acid;化合物 T14866Carboxy-PEG2-sulfonic acid (2024/9/1)
简介:carboxy-peg2-sulfonic acid is a polyethylene glycol (peg)-derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Carboprost tromethamine;卡前列素氨基丁三醇Carboprost tromethamine (2024/9/1)
简介:carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin f2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.
Caracemide;卡醋胺NSC-253272;NSC-253272|||卡醋胺 (2024/9/1)
简介:caracemide (nsc-253272) inhibits the enzyme ribonucleotide reductase of escherichia coli. caracemide can be used in anticancer studies.
Carabersat;卡拉博沙SB 204269;SB 204269 (2024/9/1)
简介:carabersat(sb 204269) is a novel and effective anticonvulsant and antiepileptic agent.
Caprylic/Capric Triglyceride;辛癸酸甘油酯Caprylic/Capric Triglyceride (2024/9/1)
简介:caprylic/capric triglyceride, a compound consisting of triglycerides and esters derived from fractionated vegetable oil, and fatty acids from coconut and palm kernel oils, serves as a food additive and is utilized in cosmetics. this substance demonstrates outstanding oxidation stability.
Camobucol;化合物 T14861AGIX 4207;AGIX 4207 (2024/9/1)
简介:camobucol is an orally active, anti-inflammatory compound. it also is a phenolic antioxidant with antirheumatic properties.
CaMKII-IN-1;化合物CaMKII-IN-1CaMKII-IN-1 (2024/9/1)
简介:camkii-in-1 is a potent and highly selective inhibitor of camkii (ic50 = 63 nm). camkii-in-1 exhibited more than 100-fold higher selectivity for camkii over camkiv, mlck, p38a, akt1, and pkc.
Oseltamivir phosphate;磷酸奥司他韦GS 4104;GS 4104|||磷酸奥司他韦 (2024/9/1)
简介:oseltamivir phosphate (gs 4104) is the phosphate salt of oseltamivir, a synthetic derivative prodrug of ethyl ester with antiviral activity. by blocking neuraminidases on the surfaces of influenza viruses, oseltamivir interferes with host cell release of complete viral particles.
Calyculin A;化合物 T14859(-)-Calyculin A;(-)-Calyculin A (2024/9/1)
简介:calyculin a is a potent and cell-permeable inhibitor of protein phosphatase 1 (pp1; ic50s: 2 nm). it also is a protein phosphatase 2a (pp2a) inhibitor (ic50s: 0.5-1 nm).
Calicheamicin;卡奇霉素Calicheamicin γ1;Calicheamicin γ1|||卡奇霉素 (2024/9/1)
简介:calicheamicin (calicheamicin γ1) is an antitumor antibiotic and is a dna synthesis inhibitor. it also is a cytotoxic agent that causes double-strand dna breaks.
Caldaret;化合物 T14857MCC-135;MCC-135 (2024/9/1)
简介:caldaret is an intracellular ca2+ handling modulator that acts through reverse mode na+/ca2+ exchanger inhibition.
Calcipotriol;卡泊三醇MC 903|||Calcipotriene;MC 903|||卡泊三醇|||Calcipotriene (2024/9/1)
简介:calcipotriol (mc 903) is a synthetic vitd3 analogue. which has a high affinity for the vitamin d receptor.
Calcein;钙黄绿素Fluorexon;Fluorexon|||钙黄绿素 (2024/9/1)
简介:calcein (fluorexon) is a fluorescent dye and self-quenching probe that used as an indicator of lipid vesicle leakage, and a complexometric indicator for titration of calcium ions with edta, and for fluorometric determination of calcium.
Caerulomycin A;浅蓝霉素Cerulomycin|||Caerulomycin;浅蓝霉素|||Cerulomycin|||Caerulomycin (2024/9/1)
简介:caerulomycin a (caerulomycin) (cerulomycin; caerulomycin) is an antifungal compound. which induces generation of t cells, enhances tgf-β-smad3 protein signaling via suppressing interferon-γ-induced stat1 signaling. antifungal and antibiotic activity, and used in autoimmune diseases.
Cabergoline;卡麦角林FCE-21336;FCE-21336|||卡麦角林 (2024/9/1)
简介:cabergoline (fce-21336) is an ergot derived-dopamine d2-like receptor agonist. it has high affinity for d2, d3, and 5-ht2b receptors (ki=0.7, 1.5, and 1.2, respectively).cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
C527;化合物C527C527 (2024/9/1)
简介:c527 is a is a pan dub enzyme inhibitor. which has a high potency for the usp1/uaf1 complex (ic50=0.88 μm).
C2-Bis-phosphoramidic acid diethyl ester;化合物 T14851C2-Bis-phosphoramidic acid diethyl ester (2024/9/1)
简介:c2-bis-phosphoramidic acid diethyl ester is an alkyl chain-derived protac linker utilized for the synthesis of protacs[1].
C-NH-Boc-C-Bis-(C1-PEG1-PFP);化合物 T14850C-NH-Boc-C-Bis-(C1-PEG1-PFP) (2024/9/1)
简介:c-nh-boc-c-bis-(c1-peg1-pfp) is a polyethylene glycol (peg)-derived protac linker, which finds application in the synthesis of protacs[1].
Methotrexate;甲氨蝶呤NCI-C04671|||WR19039|||Amethopterin|||CL14377;NCI-C04671|||WR19039|||Amethopterin|| (2024/9/1)
简介:methotrexate (wr19039) is a folate analog, an inhibitor of the dihydrofolate reductase dhfr. methotrexate has antimetabolic, antitumor, and immunosuppressive activities, and is commonly used in rheumatoid arthritis and various tumors.
Perindopril erbumine;培哚普利叔丁胺S9490-3|||Perindopril tert-butylamine salt;培哚普利叔丁胺|||培哚普利叔丁胺盐|||S9490-3| (2024/9/1)
简介:perindopril erbumine (s9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ace) inhibitor with antihypertensive activity. upon hydrolysis, perindopril erbumine (s9490-3) is converted to its active form perindoprilat, inhibiting ace and the conversion of angiotensin i to angiotensin ii; consequently, angiotensin ii-mediated vasoconstriction and angiotensin ii-stimulated aldosterone secretion from the adrenal cortex are inhibited a
C-NH-Boc-C-Bis-(C-PEG1-Boc);化合物 T14849C-NH-Boc-C-Bis-(C-PEG1-Boc) (2024/9/1)
简介:c-nh-boc-c-bis-(c-peg1-boc) is a versatile alkyl/ether-based protac linker for synthesizing protacs[1].
C 87;化合物C 87C 87 (2024/9/1)
简介:c 87 is a small-molecule tnf-α inhibitor. c 87 directly binds to tnfα, potently inhibits tnf-α-induced cytotoxicity (ic50 = 8.73 μm), and effectively blocks tnf-α-triggered signaling activities.
B I09;化合物B I09B I09 (2024/9/1)
简介:b i09, an ire-1 rnase inhibitor with an ic50 of 1230 nm, inhibits splicing of xbp1 mrna in human wac3 cells and expression of xbp-1 in lps-stimulated b cells. b i09 can be used to simulate the defects of xbp-1 in cll cells., an ire-1 rnase inhibitor with an ic50 of 1230 nm, inhibits splicing of xbp1 mrna in human wac3 cells and expression of xbp-1 in lps-stimulated b cells. b i09 can be used to simulate the defects of xbp-1 in cll cells., an ire-1 rnase inhibitor with an ic50 of 1230 nm, inhibit
Bz 423化合物Bz 423BZ48 (2024/9/1)
简介:bz 423 is a potent immunomodulator that induces apoptosis by activating bax and bak to induce mitochondrial outer membrane permeabilization and cytochrome c release.bz 423 shows partial activity in a mouse model of lupus.
BX471 hydrochloride化合物 T14845ZK-811752 hydrochloride (2024/9/1)
简介:bx471 hydrochloride (zk-811752 hydrochloride) is a potent, selective non-peptide ccr1 antagonist (ki: 1 nm for human ccr1). it shows 250-fold selectivity for ccr1 over ccr2, ccr5, and cxcr4.