9月
BX430；化合物BX430BX430 (2024/9/1)
简介：bx430 is used for chronic pain and cardiovascular disease and it is a potent and selective noncompetitive allosteric human p2x4 receptor channels antagonist with an ic50 of 0.54 μm. bx430 has species specificity.
Bifluranol；化合物BifluranolBX341；BX341 (2024/9/1)
简介：bifluranol (bx341) has anti-androgenic activity and has shown significant anti-prostatic activity in in vivo studies for the treatment of benign prostatic hyperplasia (bph).
BW 245C；化合物 BW 245CBW245C；BW245C (2024/9/1)
简介：bw 245c is a selective prostaglandin-like dp receptor (dp1) agonist, a prostaglandin analogue with inhibitory effects on the aggregation response of collagen, which can be used to study diseases such as stroke.
BVT948；化合物BVT948BVT948 (2024/9/1)
简介：bvt948 is a protein tyrosine phosphatase (ptp) inhibitor.it can also inhibit lysine methyltransferase setd8 (kmt5a) and several cytochrome p450 (p450) isoforms.
Butyrylcarnitine；丁酰肉碱Butyrylcarnitine (2024/9/1)
简介：butyrylcarnitine is a plasma metabolite that is an indicator of abnormal metabolism due to disease and is used in the diagnosis of heart failure and pancreatic cysts.
Perindoprilat；培哚普利Perindoprilate；Perindoprilate|||培哚普利 (2024/9/1)
简介：perindoprilat (perindoprilate) is an angiotensin-converting enzyme inhibitor.
Butyrolactone 3化合物 T14839Butyrolactone 3 (2024/9/1)
简介：butyrolactone 3 is a specifical inhibitor of the histone acetyltransferase gcn5 (ic50: 100 μm) with a high affinity to the gcn5 enzyme comparable to that of its natural substrate, histone h3. butyrolactone 3 shows weak inhibitory on cbp (ic50: 0.5 mm).
Butoxycarbonyl-PEG5-sulfonic acid；化合物 T14838Butoxycarbonyl-PEG5-sulfonic acid (2024/9/1)
简介：butoxycarbonyl-peg5-sulfonic acid is a peg-based protac linker utilized for synthesizing protacs[1].
Bucloxic acid；布氯酸804CB|||Bucloxonic acid|||Esfar；804CB|||Bucloxonic acid|||布氯酸|||Esfar (2024/9/1)
简介：bucloxic acid is an anti-inflammatory pyrazole derivative used in the treatment of chronic glomerular nephropathies.
BTRX-335140；化合物BTRX-335140CYM-53093；CYM-53093 (2024/9/1)
简介：btrx-335140 (cym-53093) is a potent and selective, orally active κ opioid receptor (kor) antagonist, has antagonist activity for κor, μor and δor with ic50 values of 0.8 nm, 110 nm, and 6500 nm, respectively. btrx-335140 can distribute well into the cns. admet (absorption, distribution, metabolism, excretion, and toxicity) . btrx-335140 endows with favorable in vitro admet and in vivo pharmacokinetic profiles and medication-like duration of action in rats.
BT23,6-二氯-2-苯并噻吩羧酸3,6-二氯-2-苯并噻吩羧酸 (2024/9/1)
简介：bt2, a bckdc kinase (bdk) inhibitor, exhibits an ic50 of 3.19 μm and functions as a potent, selective mcl-1 inhibitor with a ki value of 59 μm. its interaction with bdk induces helix movements in the n-terminal domain, leading to bdk´s dissociation from the branched-chain α-ketoacid dehydrogenase complex (bckdc).
BS3 Crosslinker disodium双琥珀酰亚胺辛二酸酯钠盐双琥珀酰亚胺辛二酸酯钠盐 (2024/9/1)
简介：bs3 crosslinker disodium is a non-cleavable adc linker used in antibody-drug conjugates (adcs) synthesis.
BS3 Crosslinker；化合物 T14833BS3 Crosslinker (2024/9/1)
简介：bs3 crosslinker is a non-cleavable linker employed in the synthesis of antibody-drug conjugates (adcs)[1]. it is utilized specifically for its proficiency in connecting antibodies with drugs, enhancing the overall efficiency and effectiveness of the resulting adc.
BS2G Crosslinker disodium；化合物 T14832BS2G Crosslinker disodium (2024/9/1)
简介：bs2g crosslinker (disodium) is a non-cleavable linker employed for synthesizing antibody-drug conjugates (adcs)[1].
Bryostatin 1；苔藓抑素1Bryostatin 1 (2024/9/1)
简介：bryostatin 1 is a natural macrolide isolated from the bryozoan bugula neritina and is a cns)permeable pkc modulator. bryostatin 1 binds to the isolated c1 domain of munc13-1 and the full-length munc13-1 protein (kis: 8.07 nm and 0.45 nm).
Bromperidol溴哌利多溴哌利多|||R-11333 (2024/9/1)
简介：bromperidol (r-11333) is a butyrophenone derivative and it is a potent and long-acting neuroleptic. which is used as an antipsychotic in the treatment of schizophrenia.
Citalopram hydrobromide；氢溴酸西酞普兰Lu 10-171|||Nitalapram HBr|||Bonitrile HBr|||XU-62-320|||Lu 10-171 HB (2024/9/1)
简介：citalopram hydrobromide (xu-62-320) , a selective serotonin reuptake inhibitor (ssri), selectively inhibits the cns neuronal reuptake of serotonin, thereby potentiating serotonergic activity in the central nervous system (cns). citalopram hydrobromide is the orally bioavailable hydrobromide salt of the racemic bicyclic phthalene derivative citalopram with antidepressant activity. this agent has minimal effects on the cns neuronal reuptake of norepinephrine (ne) and dopamine (da).
Bromoenol lactone；化合物 T14829(6E)-Bromoenol lactone；(6E)-Bromoenol lactone (2024/9/1)
简介：bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase a2 (ipla2β; ic50: ~7 μm). it inhibits antigen-stimulated mast cell exocytosis without blocking ca2+ influx.
Bromoacetamido-PEG8-Boc；化合物 T14828Bromoacetamido-PEG8-Boc (2024/9/1)
简介：bromoacetamido-peg8-boc is a peg-based linker compound utilized for synthesizing protacs, which are molecules designed for targeted protein degradation[1].
Bromoacetamido-PEG8-acid；化合物 T14827Bromoacetamido-PEG8-acid (2024/9/1)
简介：bromoacetamido-peg8-acid is a peg-derived protac linker suitable for synthesizing protacs[1].
Bromoacetamido-PEG5-azide；化合物 T14826Bromoacetamido-PEG5-azide (2024/9/1)
简介：bromoacetamido-peg5-azide is a polyethylene glycol (peg)-based linking molecule, commonly known as a protac linker, which is utilized for the efficient synthesis of protacs[1].
Bromoacetamido-PEG4-NHS ester；化合物 T14825Bromoacetamido-PEG4-NHS ester (2024/9/1)
简介：bromoacetamido-peg4-nhs ester is a pegylated n-hydroxysuccinimide ester compound, specifically designed as a linker for protac synthesis. this peg-based protac linker, when utilized, facilitates the creation of protein-targeted chimeras (protacs)[1].
Bromoacetamido-PEG4-C2-Boc；化合物 T14824Bromoacetamido-PEG4-C2-Boc (2024/9/1)
简介：bromoacetamido-peg4-c2-boc is a polyethylene glycol (peg)- and alkyl/ether-based linker commonly employed for the synthesis of proteolysis targeting chimeras (protacs)[1].
Bromoacetamido-PEG4-acid；化合物 T14823Bromoacetamido-PEG4-acid (2024/9/1)
简介：bromoacetamido-peg4-acid is a peg-based protac linker utilized for protac synthesis[1]. it also serves as a cleavable 4-unit peg adc linker in the synthesis of antibody-drug conjugates (adcs)[2].
Bromoacetamido-PEG3-NH-Boc；化合物 T14822Bromoacetamido-PEG3-NH-Boc (2024/9/1)
简介：bromoacetamido-peg3-nh-boc is a polyethylene glycol (peg)-based linker compound employed in the synthesis of proteolysis-targeting chimeras (protacs)[1].
Bromoacetamido-PEG3-C2-Boc；化合物 T14821Bromoacetamido-PEG3-C2-Boc (2024/9/1)
简介：bromoacetamido-peg3-c2-boc is a polyethylene glycol (peg) derived linker that is suitable for the synthesis of proteolysis-targeting chimeras (protacs) [1].
Bromoacetamido-PEG3-C2-acid；化合物 T14820Bromoacetamido-PEG3-C2-acid (2024/9/1)
简介：bromoacetamido-peg3-c2-acid is a polyethylene glycol (peg) derived linker for the synthesis of proteolysis targeting chimeras (protacs)[1].
Ciclopirox；环吡酮HOE296b；环吡酮|||HOE296b|||环吡酮胺 (2024/9/1)
简介：ciclopirox (hoe296b) exerts its action by binding to and chelating trivalent cations, such as fe3+ and al3+, thereby inhibiting the availability of essential co-factors for enzymes. ciclopirox is a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. this may lead to a loss of activity of enzymes that are essential for cellular metabolism, the organization of cell wall structure and other crucial cell functions. in addition, ciclopirox exerts
Bromoacetamido-PEG3-azide；化合物 T14819Bromoacetamido-PEG3-azide (2024/9/1)
简介：bromoacetamido-peg3-azide is a polyethylene glycol (peg)-based linker used for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Bromoacetamido-PEG2-C2-NHS ester；化合物 T14818Bromoacetamido-PEG2-C2-NHS ester (2024/9/1)
简介：bromoacetamido-peg2-c2-nhs ester is a pegylation-based linker compound utilized in protac synthesis[1].
MSN交谈
