9月
1,3-Dibromo-5,5-dimethylhydantoin；二溴海因1,3-Dibromo-5,5-dimethylhydantoin (2024/9/1)
简介：1,3-dibromo-5,5-dimethylhydantoin is an alkyl chain-based protac linker that can be used in protac synthesis.
1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane；化合物 T173201-3-bis-carboxyethoxy-2-2-bis-carboxy (2024/9/1)
简介：1,3-bis(carboxyethoxy)-2,2-bis(carboxyethoxy)propane is a polyethylene glycol (peg)-based linker compound suitable for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Semicarbazide hydrochloride；盐酸氨基脲Aminourea hydrochloride；盐酸氨基脲|||Aminourea hydrochloride (2024/9/1)
简介：semicarbazide hydrochloride (aminourea hydrochloride) is snow white crystals and used as a reagent for ketones and aldehydes with which it affords crystalline compounds having characteristic melting points.
1,2-Bis(2-iodoethoxy)ethane；1,2-双(2-碘代乙氧基)乙烷1,2-Bis(2-iodoethoxy)ethane (2024/9/1)
简介：1,2-bis(2-iodoethoxy)ethane is a peg-based protac linker. 1,2-bis(2-iodoethoxy)ethane can be used in the synthesis of mt802 and sjf620. mt-802 and sjf620 are potent protac btk degraders with dc50s of 1 nm and 7.9 nm, respectively[1].
1,1,1-Trifluoroethyl-PEG4-propargyl；化合物 T173181,1,1-Trifluoroethyl-PEG4-propargyl (2024/9/1)
简介：1,1,1-trifluoroethyl-peg4-propargyl is a polyethylene glycol (peg)-based protac linker employed for the synthesis of protacs [1].
1,1,1-Trifluoroethyl-PEG2-propargyl；化合物 T173171,1,1-Trifluoroethyl-PEG2-propargyl (2024/9/1)
简介：1,1,1-trifluoroethyl-peg2-propargyl is a polyethylene glycol (peg) derivative designed specifically to serve as a protac linker in the synthesis of protacs[1].
α-Lipoic acid-NHS；化合物 T17316DL-α-Lipoic acid-NHS；DL-α-Lipoic acid-NHS (2024/9/1)
简介：α-lipoic acid-nhs is an alkyl/ether-based protac linker utilized in the synthesis of protacs [1].
(±)-CPSI-1306；化合物cpsi-1306cpsi-1306|||2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholi (2024/9/1)
简介：(±)-cpsi-1306 (2-(3-(2,4-difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (mif) antagonist and can be used in studies about non-insulin-dependent diabetes mellitus (niddm) and the prevention of the deleterious cutaneous effects of acute and chronic uvb exposure.
(±)-BI-D；化合物 T17314(±)-BI-D (2024/9/1)
简介：(±)-bi-d is an effective allini(an allosteric in inhibitor) that binds integrase at the ledgf/p75 binding site (ic50: 2.4–2.9 μm).
(+)-SJ733；化合物n(+)-SJ733SJ000557733；SJ000557733 (2024/9/1)
简介：(+)-sj733 (sj000557733) is a potent na+-atpase pfatp4 inhibitor with antimalarial activity for the study of malaria.
(+)-Phenserine；化合物 T17312(+)-Phenserine (2024/9/1)
简介：(+)-phenserine is a novel selective inhibitor of cholinesterase non-competitive (ic50: 45.3 μm).
(+)-JQ1 PA；化合物(+)-JQ1 PA(+)-JQ1 PA (2024/9/1)
简介：(+)-jq1 pa is a derivative of the bromodomain and extra-terminal (bet) inhibitor jq1(ic50 of 10.4 nm).
Phenylephrine；去氧肾上腺素L-Phenylephrine|||(R)-(-)-Phenylephrine；去氧肾上腺素|||L-Phenylephrine|||去氧肾上腺素碱|||(R) (2024/9/1)
简介：phenylephrine ((r)-(-)-phenylephrine) is a selective α1-adrenoceptor agonist ( pki: 5.86, 4.87 and 4.70 for α1d, α1b, and α1a receptors respectively).
TAME hydrochlorideNA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐NA-P-甲苯磺酰-L-精氨酸甲酯盐酸盐|||Tos-Arg-OMe HCl|||TOS-ARG-OME hydrochlo (2024/9/1)
简介：tame hydrochloride (tos-arg-ome hcl) is a kind od amino acid derivatives.
(R)-(-)-Ibuprofen；(R)-(-)-布洛芬levibuprofen|||(R)-Ibuprofen；levibuprofen|||(R)-Ibuprofen (2024/9/1)
简介：(r)-(-)-ibuprofen ((r)-ibuprofen) is the r enantiomer of ibuprofen and inhibits nf-κb activation. (r)-(-)-ibuprofen has anti-inflammatory and antinociceptive effects.
(R)-Oxiracetam奥拉西坦奥拉西坦|||(R)-(+)-Oxiracetam (2024/9/1)
简介：(r)-oxiracetam is the (r)-enantiomer of the nootropic drug oxiracetam. oxiracetam is a nootropic drug of the racetam family and stimulant.
(R)-Ofloxacin；(R)-氧氟沙星DR3354|||D-Ofloxacin|||DR-3354|||DR 3354|||(R)-(+)-Ofloxacin|||(+)-Ofloxacin；D (2024/9/1)
简介：(r)-ofloxacin is a r-isomer of ofloxacin, an antibiotic used to treat a number of bacterial infections.
(R)-Baclofen hydrochloride；(R)-巴氯芬盐酸盐Arbaclofen hydrochloride；Arbaclofen hydrochloride|||(R)-巴氯芬盐酸盐 (2024/9/1)
简介：arbaclofen hydrochloride, a gamma-aminobutyric acid derivative, is a specific agonist of gaba-b receptors, it is used to treat spasticity, especially that due to spinal cord damage. it acts at spinal and supraspinal sites, generally reduces excitatory transmission.
CDK8-IN-4；化合物 T17305CDK8-IN-4 (2024/9/1)
简介：cdk8-in-4 is an inhibitor of cdk8 (ic50: 0.2 nm).
α-Tocopherol phosphateα-生育酚磷酸盐vitamin E phosphate|||TocP|||alpha-Tocopherol phosphate|||α-生育酚磷酸盐 (2024/9/1)
简介：α-tocopherol phosphate is the compound demonstrating the highest vitamin e activity.
α-Cyclodextrin；α-环糊精Alfadex|||NSC269470|||NSC 269470|||NSC-269470；Alfadex|||NSC269470|||α-环糊精|||NSC (2024/9/1)
简介：α-cyclodextrin (alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.
(9Z,11E)-Prodlure；化合物 T17302(9Z,11E)-Prodlure|||Litlure A|||(9Z,11E)-Tetradecadien-1-yl acetate|| (2024/9/1)
简介：(9z, 11e) - prodlure is the main component of the sex pheromone of female spodoptera littoralis.
opigolix；化合物 T17301opigolix (2024/9/1)
简介：opigolix is a gonadotropin-releasing hormone receptor antagonist.
(-)-(S)-B-973B；化合物(-)-(S)-B-973B(-)-(S)-B-973B (2024/9/1)
简介：(-)-(s)-b-973b is an effective allosteric agonist and a positive allosteric modulator of α7 nachr.
NPS-2143；化合物NPS 2143SB262470|||NPS 2143|||SB 262470A；SB262470|||NPS 2143|||SB 262470A|||2-氯-6-[(2R)- (2024/9/1)
简介：nps-2143 (sb 262470a) is a novel potent and selective antagonist of ca(2+) receptor.
(-)-Indolactam V；化合物 T17299Indolactam V；Indolactam V (2024/9/1)
简介：(-)-indolactam v is a pkc activator (kis: 3.36 nm, 1.03 μm for η-crd2 , γ-crd2). (-)-indolactam v also has the kds are 5.5 nm (η-c1b), 7.7 nm (ε-c1b), 8.3 nm (δ-c1b), 18.9 nm (β-c1a-long), 20.8 nm (α-c1a-long), 137 nm (β-c1b), 138 nm (γ-c1a), 213 nm (γ-c1b). it has antitumor activity.
Zylofuramine；化合物 T17298Zylofuramine (2024/9/1)
简介：zylofuramine is a stimulant of psychomotor.
ZXH-3-26；化合物 T17297ZXH-3-26 (2024/9/1)
简介：zxh-3-26 is a selective degrader of the protac brd4 (dc50/5h: ~ 5 nm).
Zotatifin；化合物 T17296eFT226；eFT226 (2024/9/1)
简介：zotatifin is a potent and well-tolerated eif4a inhibitor. zotatifin promotes eif4a binding to specific mrna sequences with recognition motifs in the 5’-utrs (ic50=2 nm). zotatifin effectively reduces viral infectivity by inhibiting sars-cov-2 np protein biogenesis (ic90=37 nm).
ZM39923；化合物 T17295ZM39923 (2024/9/1)
简介：zm39923 is a jak3 inhibitor (pic50: 7.1). zm39923 also effectively inhibits tissue transglutaminase (ic50: 10 nm).
MSN交谈
