9月
ZL0454；化合物 T17294ZL0454 (2024/9/1)
简介：zl0454 is an effective and selective bromodomain-containing protein 4 inhibitors (ic50: 49 and 32 nm for bd1 and bd2).
ZL006；化合物ZL006ZL006 (2024/9/1)
简介：zl006 is an effective inhibitor of nnos/psd-95 interaction. zl006 also inhibits nmda receptor-mediated no synthesis.
ZK159222；化合物 T17292ZK159222 (2024/9/1)
简介：zk159222 is an effective 1α,25-(oh)2d3 receptor (vdr) agonist. zk159222 has a partial agonistic character.
ZK 216348；化合物 T17291(+)-ZK 216348；(+)-ZK 216348 (2024/9/1)
简介：zk 216348 also binds to progesterone and mineralocorticoid receptors (ic50s: 20.4 nm and 79.9 nm, respectively). zk 216348 is a nonsteroidal selective glucocorticoid receptor agonist (ic50: 20.3 nm). zk 216348 has an anti-inflammatory activity similar to prednisolone.
ZED-1227；化合物ZED-1227ZED-101|||TAK-227；ZED-101|||TAK-227 (2024/9/1)
简介：zed-1227 (tak-227) is an orally active, selective and potent transglutaminase 2 (tg2) inhibitor with anticancer activity that blocks inflammation-induced tg2 expression and activation for the treatment of celiac disease.
ZD8321；化合物 T17288ZD8321 (2024/9/1)
简介：zd8321 is an effective inhibitor of human neutrophil elastase (ki: 13±1.7 nm).
ZD-1611；化合物 T17287ZD-1611 (2024/9/1)
简介：zd-1611 is an effective and selective eta receptor antagonist. it is used for the research of ischemic stroke.
Zaurategrast；化合物 T17286CT7758；CT7758 (2024/9/1)
简介：zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.
Zatosetron maleate；扎托司琼马来酸盐LY 277359 maleate；LY 277359 maleate (2024/9/1)
简介：zatosetron maleate（ly 277359 maleate） is a potent and selective serotonin 5ht3 receptor antagonist for the study of acute migraine.
Zardaverine；扎达维林BY 290|||B 84290；BY 290|||B 84290 (2024/9/1)
简介：zardaverine (by 290) is an orally available, selective and potent pde3/4 inhibitor with bronchodilator activity and anti-hepatocarcinogenic activity.zardaverine´s action in platelets is mediated by pde iii isoenzymes and can be used in studies of acute renal failure and chronic airflow obstruction.
Zamifenacin；化合物 T17283UK-76654；UK-76654 (2024/9/1)
简介：zamifenacin obviously decreases colonic motility in irritable bowel syndrome. zamifenacin is an effective gut-selective muscarinic m3 receptor antagonist.
Z-Ile-Leu-aldehyde；化合物 T17281Z-IL-CHO|||GSI-XII|||γ-Secretase inhibitor XII；Z-IL-CHO|||GSI-XII|||γ-S (2024/9/1)
简介：z-ile-leu-aldehyde is an effective and competitive peptide aldehyde inhibitor of γ-secretase and notch.
(Z)-Guggulsterone；孕二烯二酮(Z)-Guggulsterone (2024/9/1)
简介：(z)-guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. z-guggulsterone inhibits angiogenesis by suppressing the vegf–vegf-r2–akt signaling axis.
Z-321；化合物 T17279Z-321 (2024/9/1)
简介：z-321 is an inhibitor of prolyl endopeptidase.
YUKA1；化合物 T17278YUKA1 (2024/9/1)
简介：yuka1 is a potent and cell-permeable lysine demethylase 5a inhibitor (ic50: 2.66 μm) and less active on kdm5c (ic50, 7.12 μm). yuka1 is inactive on kdm5b, kdm6a, or kdm6b.
YS-201；化合物 T17277YS-201 (2024/9/1)
简介：ys-201 is an antagonist of dihydropyridine-type calcium channel.
Zonampanel；唑南帕奈YM 872；YM 872|||唑南帕奈 (2024/9/1)
简介：zonampanel is a selective glutamate receptor subtype, α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor antagonist.
YM348；化合物 T17275YM348 (2024/9/1)
简介：ym348 is an effective and orally active 5-ht2c receptor agonist. ym348 also shows a high affinity for the cloned human 5-ht2c receptor (ki: 0.89 nm).
YM022化合物 T17274YM022|||YM-022 (2024/9/1)
简介：ym022 is a highly effective and selective gastrin/cholecystokinin (cck)-b receptor antagonist. ym022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo. ym022 shows the ki values of 68 pm and 63 nm for cck-b and cck-a receptor, respectively.
YM-254890；化合物 T17273YM-254890 (2024/9/1)
简介：ym-254890 inhibits platelet aggregation induced by adp by blocking the p2y1 signal transduction pathway (ic50: below 0.6 μm). ym-254890 is a selective gαq/11 protein inhibitor. ym-254890 displays no inhibition of other g protein subtypes.
YKL-06-062；化合物YKL-06-062YKL-06-062 (2024/9/1)
简介：ykl-06-062 is a second-generation salt-inducible kinase (sik) inhibitor that inhibits sik1, sik2 and sik3 with ic50s of 2.12 nm, 1.40 nm and 2.86 nm.
YKL-05-099；化合物YKL-05-099YKL-05-099 (2024/9/1)
简介：ykl-05-099 is an inhibitor of the salt-inducible kinase(sik1 and sik3 ; ic50s: 10 and 30 nm, respectively). it has a slightly less potent sik2-inhibitory (ic50:40 nm).
4-Cyclohexyl-1-phenylthiosemicarbazide；4-环己基-1-苯氨基硫脲4-Cyclohexyl-1-phenylthiosemicarbazide (2024/9/1)
简介：4-cyclohexyl-1-phenylthiosemicarbazide is employed as an intermediate.
Y-27152；化合物 T17269Y-27152 (2024/9/1)
简介：y-27152 is a prodrug of the katp (kir6) channel opener y-26763 and is a long-acting k+ channel opener.
Y-26763化合物 T17268Y 26763|||Y26763 (2024/9/1)
简介：y-26763 is a k+ channel opener and active metabolite of y-27152. this is an atp-sensitive k+ (katp) channel activator.
XL228；化合物XL228XL228 (2024/9/1)
简介：xl228 is an inhibitor of multi-targeted tyrosine kinase (ic50s: 5, 3.1, 1.6, 6.1, 2 nm for bcr-abl, aurora a, igf-1r, src, and lyn, respectively).
Xipamide；希伯胺Diurexan|||Aquaphor；希伯胺|||Diurexan|||Aquaphor (2024/9/1)
简介：xipamide (diurexan) is a sulfonamide-based diuretic with antihypertensive properties. xipamide selectively inhibits anion exchanger.
Ximelagatran；希美加群EXANTA|||H 376-95|||H37695|||H 376/95|||H-37695|||H 37695；EXANTA|||H 376-95|||H3769 (2024/9/1)
简介：ximelagatran (h 376-95), a direct thrombin inhibitor, can be taken orally and acts solely by inhibiting the actions of thrombin. ximelagatran is converted to the active agent melagatran in vivo.
Xenalamine；联苯酰胺苯酸Xenazoic acid|||CV58903；Xenazoic acid|||联苯酰胺苯酸|||CV58903 (2024/9/1)
简介：xenalamine is a synthetic compound of antiviral.
XE 991 dihydrochloride；化合物XE 991 dihydrochlorideXE 991 dihydrochloride (2024/9/1)
简介：xe 991 dihydrochloride is a kv7 (kcnq) channel blocker. xe 991 dihydrochloride potently inhibits kv7.1 (kcnq1), kv7.2 (kcnq2), kv7.2 + kv7.3 (kcnq3) channel, and m-current (ic50s: 0.75 μm, 0.71 μm, 0.6 μm, and 0.98 μm, respectively).
MSN交谈
