9月
Azide-PEG-amine (MW 5000)；化合物 T17459Azide-PEG-amine (MW 5000) (2024/9/1)
简介：azide-peg-amine (mw 5000) is a polyethylene glycol (peg)-derived linker compound with azide functionality, primarily utilized in the synthesis of proteolysis-targeting chimeras (protacs)[1].
Azide-PEG-amine (MW 3500)；化合物 T17458Azide-PEG-amine (MW 3500) (2024/9/1)
简介：azide-peg-amine (mw 3500) is a polyethylene glycol (peg) derived linker compound, specifically designed for the synthesis of proteolysis targeting chimeric molecules (protacs)[1].
Azide-PEG-amine (MW 2000)；化合物 T17457Azide-PEG-amine (MW 2000) (2024/9/1)
简介：azide-peg-amine (mw 2000) is a polyethylene glycol (peg) derived linker compound utilized in the synthesis of proteolysis targeting chimeras (protacs)[1].
Azide-PEG-alcohol (MW 2000)；化合物 T17456Azide-PEG-alcohol (MW 2000) (2024/9/1)
简介：azide-peg-alcohol, a polyethylene glycol (peg)-based protac linker with a molecular weight of 2000, functions as a versatile option for the synthesis of protacs[1].
AZD-CO-C2-Ph-amido-Ph-azide；化合物 T17455AZD-CO-C2-Ph-amido-Ph-azide (2024/9/1)
简介：azd-co-c2-ph-amido-ph-azide is an alkyl chain-derived protac linker suitable for protacs synthesis[1].
ATP-polyamine-biotin；ATP多胺生物素ATP polyamine biotin|||ATPpolyaminebiotin|||ATP-polyamine-biotin；ATP po (2024/9/1)
简介：atp-polyamine-biotin is a cell-permeable, efficient kinase cosubstrate with conversions and kinetics similar to those of other known atp analogues. apb shows a cytotoxicity ec50 value of 19 ± 1 mm. atp-polyamine-biotin is shown to promote biotin labeling of kinase substrates in live cells and has future applications in phosphoprotein purification and analysis. apb is cell-permeable and nontoxic at low mm concentrations, with cell penetration and labeling dependent on the polyamine linker.
APN-PEG4-tetrazine；化合物 T17453APN-PEG4-tetrazine (2024/9/1)
简介：apn-peg4-tetrazine is a cleavable adc linker compound comprised of four peg units, specifically designed for the synthesis of antibody-drug conjugates (adcs)[1].
APN-PEG4-PFP；化合物 T17452APN-PEG4-PFP (2024/9/1)
简介：apn-peg4-pfp is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
APN-PEG4-DBCO；化合物 T17451APN-PEG4-DBCO (2024/9/1)
简介：apn-peg4-dbco is a cleavable linker for antibody-drug conjugates (adcs), comprised of a four-unit peg and a dbco moiety. it finds application in the synthesis of adcs[1].
APN-PEG4-BCN；化合物 T17450APN-PEG4-BCN (2024/9/1)
简介：apn-peg4-bcn is a cleavable four-unit polyethylene glycol (peg) linker, employed in the synthesis of antibody-drug conjugates (adcs)[1].
Balipodect；化合物TAK-063TAK063|||TAK-063|||TAK 063；TAK063|||TAK-063|||TAK 063 (2024/9/1)
简介：balipodect (tak063) is a highly effective and selective pde10a inhibitor (ic50: 0.30 nm); its selectivity is >15000-fold over other pdes.
APN-PEG4-Amine hydrochloride；化合物 T17449APN-PEG4-Amine hydrochloride (2024/9/1)
简介：apn-peg4-amine (hydrochloride) is a cleavable four-unit polyethylene glycol (peg) linker utilized in the synthesis of antibody-drug conjugates (adcs)[1].
AmPEG6C2-Aur0131；化合物 T17448AmPEG6C2-Aur0131 (2024/9/1)
简介：ampeg6c2-aur0131 is a drug-linker conjugate designed for anti-cxcr4 adc applications, showcasing potent antitumor activity. it incorporates aur0131, an auristatin-based microtubule inhibitor, connected through the non-cleavable ampeg6c2 linker.
Aminoxyacetamide-PEG3-azide；化合物 T17447Aminoxyacetamide-PEG3-azide (2024/9/1)
简介：aminoxyacetamide-peg3-azide is a non-cleavable 3-unit polyethylene glycol linker employed for antibody-drug conjugate (adc) synthesis[1].
Aminooxy-PEG-OH (MW 2000)；化合物 T17446Aminooxy-PEG-OH (MW 2000) (2024/9/1)
简介：aminooxy-peg-oh (mw 2000) serves as a peg-based protac linker for the synthesis of protacs[1].
Aminooxy-amido-PEG4-propargyl；化合物 T17445Aminooxy-amido-PEG4-propargyl (2024/9/1)
简介：aminooxy-amido-peg4-propargyl is a 4-unit peg adc linker that is non-cleavable and specifically designed for the synthesis of antibody-drug conjugates (adcs)[1].
Amino-Tri-(m-PEG4-ethoxymethyl)-methane；化合物 T17444Amino-Tri-(m-PEG4-ethoxymethyl)-methane (2024/9/1)
简介：amino-tri-(m-peg4-ethoxymethyl)-methane, a peg-based protac linker, serves as a valuable component for synthesizing protacs[1].
Amino-SS-PEG12-acid；化合物 T17443Amino-SS-PEG12-acid (2024/9/1)
简介：amino-ss-peg12-acid, a cleavable 12-unit polyethylene glycol (peg) linker, is commonly used in the synthesis of antibody-drug conjugates (adcs)[1].
Amino-PEG9-amido-C16-Boc；化合物 T1744217-(Amino-PEG9-ethylcarbamoyl)heptadecanoic t-butyl ester；17-(Ami (2024/9/1)
简介：amino-peg9-amido-c16-boc is a polyethylene glycol (peg)-based linker utilized for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Amino-PEG9-alcohol胺基-九聚乙二醇胺基-九聚乙二醇 (2024/9/1)
简介：amino-peg9-alcohol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Amino-PEG7-acid氨基-七聚乙二醇-羧酸氨基-七聚乙二醇-羧酸 (2024/9/1)
简介：amino-peg7-acid is a peg-based protac linker that can be used in protac synthesis.
BIX02188；化合物BIX02188BIX02188 (2024/9/1)
简介：bix02188 is a selective and potent mek5 inhibitor that inhibits mek5-induced apoptosis in cells expressing the oncogenic mutant flt3-itd.
Amino-PEG6-Thalidomide；化合物 T17439Amino-PEG6-Thalidomide (2024/9/1)
简介：amino-peg6-thalidomide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Amino-PEG6-amido-C16-COOH；化合物 T1743817-(Amino-PEG6-ethylcarbamoyl)heptadecanoic acid；17-(Amino-PEG6- (2024/9/1)
简介：amino-peg6-amido-c16-cooh, a peg-based protac linker, facilitates the synthesis of protacs[1].
Amino-PEG6-amido-C16-Boc；化合物 T1743717-(Amino-PEG6-ethylcarbamoyl)heptadecanoic t-butyl ester；17-(Ami (2024/9/1)
简介：amino-peg6-amido-c16-boc is a peg-based protac linker employed for the synthesis of protacs[1].
Amino-PEG6-amido-bis-PEG5-N3；化合物 T17436Amino-PEG6-amido-bis-PEG5-N3 (2024/9/1)
简介：amino-peg6-amido-bis-peg5-n3 is a cleavable 11-unit polyethylene glycol (peg) linker that finds application in the synthesis of antibody-drug conjugates (adcs) [1].
Amino-PEG4-Val-Cit-PAB-MMAE；化合物 T17435Amino PEG4 Val Cit PAB MMAE|||Amino-PEG-4-Val-Cit-PAB-MMAE|||A (2024/9/1)
简介：amino-peg4-val-cit-pab-mmae is a cleavable tetraethylene glycol (4 unit peg) antibody-drug conjugate (adc) linker employed in the synthesis of adcs[1].
Amino-PEG4-benzyl ester；化合物 T17434Amino-PEG4-benzyl ester (2024/9/1)
简介：amino-peg4-benzyl ester, a peg- and alkyl/ether-based protac linker, serves as a valuable component for the synthesis of protacs[1].
Amino-PEG36-CONH-PEG36-acid；化合物 T17433Amino-PEG36-CONH-PEG36-acid (2024/9/1)
简介：amino-peg36-conh-peg36-acid is a polyethylene glycol (peg)-based linker with amino and carboxylic acid functionalities. it finds utility in the synthesis of proteolysis targeting chimeras (protacs)[1].
Amino-PEG36-CH2-Boc；化合物 T17432Amino-PEG36-CH2-Boc (2024/9/1)
简介：amino-peg36-ch2-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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