9月
Dipyridamole；双嘧达莫Persantin|||Dypyridamole|||Dipyridamol|||NSC-515776|||Dipyudamine；Persantin|||Dypyr (2024/9/1)
简介：dipyridamole (persantin) is a platelet aggregation inhibitor. the physiologic effect of dipyridamole is by means of decreased platelet aggregation.
N-(Azido-PEG2)-N-Boc-PEG3-NHS ester；化合物 T16179N-(Azido-PEG2)-N-Boc-PEG3-NHS ester (2024/9/1)
简介：the peg-based protac linker, n-(azido-peg2)-n-boc-peg3-nhs ester, is suitable for the synthesis of protacs[1].
N-(Azido-PEG2)-N-Boc-PEG3-Boc；化合物 T16178N-(Azido-PEG2)-N-Boc-PEG3-Boc (2024/9/1)
简介：n-(azido-peg2)-n-boc-peg3-boc is a peg-based protac linker, suitable for the synthesis of protacs[1].
N-(Azido-PEG2)-N-Boc-PEG3-acid；化合物 T16177N-(Azido-PEG2)-N-Boc-PEG3-acid (2024/9/1)
简介：n-(azido-peg2)-n-boc-peg3-acid is a polyethylene glycol (peg) derived linker compound, specifically designed for protac synthesis[1].
N-(Azido-PEG2)-N-bis(PEG4-Boc)；化合物 T16176N-(Azido-PEG2)-N-bis(PEG4-Boc) (2024/9/1)
简介：n-(azido-peg2)-n-bis(peg4-boc) is a polyethylene glycol (peg)-based protac linker, employed for the efficient synthesis of proteolysis targeting chimeras (protacs)[1].
N-(Aminooxy-PEG3)-N-bis(PEG4-Boc)；化合物 T16175N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) (2024/9/1)
简介：n-(aminooxy-peg3)-n-bis(peg4-boc) is a polyethylene glycol (peg)-based linker primarily utilized in protac synthesis for the development of proteolysis-targeting chimeras (protacs)[1].
N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl)；化合物 T16174N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) (2024/9/1)
简介：n-(aminooxy-peg2)-n-bis(peg3-propargyl) is a polyethylene glycol (peg) derivative commonly employed as a peg-based linker in the manufacturing of proteolysis-targeting chimeras (protacs)[1].
N-(Amino-PEG5)-N-bis(PEG4-acid)；化合物 T16173N-(Amino-PEG5)-N-bis(PEG4-acid) (2024/9/1)
简介：n-(amino-peg5)-n-bis(peg4-acid) is a peg-based protac linker employed for synthesizing protacs. it comprises an amino group with two terminal carboxylic acids[1].
N-(Amino-PEG4)-N-bis(PEG4-Boc)；化合物 T16172N-(Amino-PEG4)-N-bis(PEG4-Boc) (2024/9/1)
简介：n-(amino-peg4)-n-bis(peg4-boc) is a polyethylene glycol (peg)-based linker, utilized for the synthesis of proteolysis targeting chimeras (protacs)[1].
N-(Amino-PEG3)-N-bis(PEG3-Boc)；化合物 T16171N-(Amino-PEG3)-N-bis(PEG3-Boc) (2024/9/1)
简介：n-(amino-peg3)-n-bis(peg3-boc) is a polyethylene glycol-based linker utilized in the synthesis of proteolysis targeting chimeras (protacs)[1].
N-(Amino-PEG3)-N-bis(PEG3-acid)；化合物 T16170N-(Amino-PEG3)-N-bis(PEG3-acid) (2024/9/1)
简介：n-(amino-peg3)-n-bis(peg3-acid) is a polyethylene glycol (peg)-based linker compound utilized for synthesizing proteolysis-targeting chimeras (protacs)[1].
Enrofloxacin；恩诺沙星BAY-Vp2674|||PD160788；恩诺沙星|||BAY-Vp2674|||PD160788 (2024/9/1)
简介：enrofloxacin (bay-vp2674) is a veterinary antibacterial agent, used in poultry.
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride；化合物N-alpha-Tosyl-L-lysine chloromethyl keto (2024/9/1)
简介：n-alpha-tosyl-l-lysine chloromethyl ketone hydrochloride (n-alpha-tosyl-l-lysine_chloromethyl_ketone_hydrochloride) is an inhibitor of trypsin-like protease. n-alpha-tosyl-l-lysine chloromethyl ketone hydrochloride exhibits an inhibitory effect on ifn-γ activities.
N-(acid-PEG3)-N-bis(PEG3-azide)；化合物 T16168N-(acid-PEG3)-N-bis(PEG3-azide) (2024/9/1)
简介：n-(acid-peg3)-n-bis(peg3-azide) is a peg-based protac linker employed in the synthesis of protacs[1].
N-(4-Carboxycyclohexylmethyl)maleimide；化合物 T16167N-(4-Carboxycyclohexylmethyl)maleimide (2024/9/1)
简介：n-(4-carboxycyclohexylmethyl)maleimide is an alkyl chain-based protac linker suitable for synthesizing protacs[1].
N-[(4-Aminophenyl)methyl]adenosine；N-[(4-氨基苯基)甲基]腺苷N-[(4-Aminophenyl)methyl]adenosine (2024/9/1)
简介：n-[(4-aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (ki: 29 nm for rat ecto-5′-nucleotidase).
Myriocin多球壳菌素ISP-I|||Thermozymocidin (2024/9/1)
简介：myriocin (thermozymocidin), a metabolite derived from myriococcum albomyces, is a serine-palmitoyltransferase (spt) inhibitor with potential antitumour, anticancer, and antiparasitic activities.myriocin inhibits tumour growth by regulating macrophage polarisation and function through the pi3k/akt/mtor pathway.myriocin inhibits hcv infection and can be used in the study of neurological diseases. myriocin inhibits hcv infection and can be used to study neuropathy and fungal infections.
MY-5445；化合物MY-5445N-(3-chlorophenyl)-4-phenylphthalazin-1-amine；N-(3-chlorophenyl)-4-phenylphthalazi (2024/9/1)
简介：my-5445 (n-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (pde5). my-5445 selectively inhibits cgmp pde (ki:1.3 μm).
MV1；化合物MV1MV1 (2024/9/1)
简介：mv1 is an iap antagonist. when combined with halotag ligand, mv1 causes protein knockdown of halotag-fused proteins.
Mutated EGFR-IN-1；AZD9291中间体1Osimertinib analog；Osimertinib analog|||AZD9291中间体1 (2024/9/1)
简介：mutated egfr-in-1 (osimertinib analog) is a useful intermediate for the inhibitors design for mutated egfr, such as l858r egfr, exonl9 deletion activating mutant, and t790m resistance mutant.
Mutant IDH1 inhibitor；化合物Mutant IDH1 inhibitorMutant IDH1 inhibitor (2024/9/1)
简介：mutant idh1 inhibitor is an effective inhibitor of mutant idh1 r132h (ic50: < 72 nm).
Musk tibetene；化合物 T16160Musk tibetine；Musk tibetine (2024/9/1)
简介：musk tibetine reveals no genotoxicity in the micronucleus test with human lymphocytes and human hepatoma cell lines. musk tibetene is a nitro musk compound with carcinogenic activity.
Cefotiam hydrochloride；盐酸头孢替安Pansporin|||SCE-963 hydrochloride|||Pansporine|||Cefotiam dihydrochlori (2024/9/1)
简介：cefotiam hydrochloride (sce-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. cefotiam binds to penicillin-binding proteins (pbps), transpeptidases that are responsible for crosslinking of peptidoglycan. by preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
Irbesartan HCl；化合物 T1615LIrbesartan hydrochloride|||BMS186295|||BMS 186295|||BMS-186295；Irbesartan h (2024/9/1)
简介：irbesartan is an angiotensin ii receptor antagonist used mainly for the treatment of hypertension. it selectively and competitively blocks the binding of angiotensin ii to the angiotensin i receptor.
Muramyl dipeptide；佐剂肽MDP；MDP (2024/9/1)
简介：muramyl dipeptide (mdp) is a synthetic immunoreactive peptide, consisting of n-acetyl muramic acid attached to a short amino acid chain of l-ala-d-isogln. muramyl dipeptide indirectly decreases osteoclast differentiation through a decreased rankl/opg ratio. muramyl dipeptide directly increases osteoblast differentiation by up-regulating runx2 gene expression through mapk pathways. muramyl dipeptide is an inducer of bone formation through the induction of runx2 .
PF-02575799；化合物 T16158PF-02575799 (2024/9/1)
简介：pf-02575799 is an inhibitor of microsomal triglyceride transfer protein (mtp) (ic50: 0.77±0.29 nm).
MT-802；化合物MT-802MT-802 (2024/9/1)
简介：mt-802 is an effective btk degrader based on protac technology (dc50: 1 nm). mt-802 has the potential to treat c481s mutant chronic lymphocytic leukemia (cll).
MT 63-78；化合物MT 63-78MT 63-78 (2024/9/1)
简介：mt 63-78 is a specific and effective direct ampk activator (ec50: 25 μm). mt 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mtorc1 pathways. mt 63-78 has antitumor effects. mt 63–78 also causes cell mitotic arrest and apoptosis.
MSN-125；化合物 T16155MSN-125 (2024/9/1)
简介：msn-125 effectively inhibits bax/bak-mediated apoptosis in hct-116, bmk cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. msn-125 is an effective bax and bak oligomerization inhibitor. msn-125 prevents mitochondrial outer membrane permeabilization (momp) (ic50: 4 μm).
MS417；化合物MS417GTPL7512；GTPL7512 (2024/9/1)
简介：ms417 (gtpl7512) is an inhibitor of bet-specific brd4(brd4-bd1 and brd4-bd2 with ic50s of 30, 46 nm and kds of 36.1, 25.4 nm, respectively), with weak selectivity at cbp brd with ic50 of 32.7 μm.
MSN交谈
