N33-TEG-COOH;化合物 T1626214-Azido-3,6,9,12-tetraoxatetradecanoic acid|||N3-TEG-COOH;14-Azido-3,6,9,12- (2024/9/1)
简介:n33-teg-cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N3-PEG8-CH2COOH;化合物 T16261N3-PEG8-CH2COOH (2024/9/1)
简介:n3-peg8-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N3-PEG4-C2-Pfp ester;化合物 T16260N3-PEG4-C2-Pfp ester (2024/9/1)
简介:n3-peg4-c2-pfp ester is a four-unit polyethylene glycol linker, noncleavable in nature, specifically employed in the fabrication of antibody-drug conjugates (adcs).
Prostaglandin E1;前列地尔PGE1|||Alprostadil;前列地尔|||PGE1|||列腺素E1|||Alprostadil (2024/9/1)
简介:prostaglandin e1 (alprostadil) is the naturally occurring prostaglandin e1 (pge1) which displays a variety of pharmacologic actions. prostaglandin e1 is a potent vasodilator agent that increases peripheral blood flow, inhibits platelet aggregation, and induces bronchodilation. used in the treatment of erectile dysfunction, this agent produces corporal smooth muscle relaxation by binding to pge receptors, resulting in the activation of adenylate cyclase and the subsequent accumulation of 3´
N3-PEG4-C2-NHS ester;化合物 T16259N3-PEG4-C2-NHS ester (2024/9/1)
简介:n3-peg4-c2-nhs ester is a four-unit polyethylene glycol (peg) linker that is noncleavable, serving as a crucial component in the synthesis of antibody-drug conjugates (adcs).
N3-PEG3-CH2CH2COOH;化合物 T16258N3-PEG3-CH2CH2COOH (2024/9/1)
简介:n3-peg3-ch2ch2cooh, a peg-based protac linker, is utilized in the synthesis of bi-3663, bi-4216, and bi-0319. additionally, azido-peg3-acid, a non-cleavable 3-unit peg adc linker, is employed in the synthesis of antibody-drug conjugates (adcs).
N3-PEG3-CH2CH2-Boc;化合物 T16257N3-PEG3-CH2CH2-Boc (2024/9/1)
简介:n3-peg3-ch2ch2-boc is a cleavable 3 unit polyethylene glycol (peg) adc linker utilized in the synthesis of antibody-drug conjugates (adcs)[1]. this compound also functions as a peg- and alkyl/ether-based proteolysis targeting chimera (protac) linker, suitable for the construction of protac molecules[2].
N3-PEG3-C2-PFP ester;化合物 T16256N3-PEG3-C2-PFP ester (2024/9/1)
简介:n3-peg3-c2-pfp ester is a 3-unit polyethylene glycol (peg) linker devoid of cleavable bonds. it is commonly employed in the synthesis of antibody-drug conjugates (adcs).
N3-PEG3-C2-NHS ester;化合物 T16255N3-PEG3-C2-NHS ester (2024/9/1)
简介:n3-peg3-c2-nhs ester is a noncleavable trifunctional polyethylene glycol (peg) linker, designed for the conjugation of antibody-drug conjugates (adcs).
N3-PEG2-C2-PFP ester;化合物 T16254N3-PEG2-C2-PFP ester (2024/9/1)
简介:the n3-peg2-c2-pfp ester, a nonclaevable 2-unit polyethylene glycol (peg) linker, is commonly employed in the synthesis of antibody-drug conjugates (adcs).
N3-PEG2-C2-NHS ester;化合物 T16253N3-PEG2-C2-NHS ester (2024/9/1)
简介:n3-peg2-c2-nhs ester is a two-unit peg linker, noncleavable in nature, specifically designed for the synthesis of antibody-drug conjugates (adcs).
N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl);化合物 T16252N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl (2024/9/1)
简介:n-(t-boc-aminooxy-peg2)-n-bis(peg3-propargyl) is a polyethylene glycol (peg) derivative specifically designed as a linker for protac synthesis [1].
N-Succinimidyl-S-acetylthioacetate;N-丁二酸,S-乙酰基巯基乙二醇酯SATA;SATA|||N-丁二酸,S-乙酰基巯基乙二醇酯 (2024/9/1)
简介:n-succinimidyl-s-acetylthioacetate (sata) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecules for later reaction with sulfhydryl reactive crosslinkers such as sulfo-smcc, sulfo-mbs, etc.
N-Succinimidyl 3-(Bromoacetamido)propionate;化合物 T162503-(2-Bromoacetamido)propanoic acid NHS ester;3 (2024/9/1)
简介:n-succinimidyl 3-(bromoacetamido)propionate is a peg-based protac linker employed in the synthesis of protacs and antibody-drug conjugates (adcs) [1, 2]. it acts as a cleavable adc linker, facilitating the conjugation of drugs to antibodies for targeted delivery [2].
Lomefloxacin hydrochloride;盐酸洛美沙星Lomefloxacin HCl|||Okacyn|||Maxaquin;Lomefloxacin HCl|||盐酸洛美沙星|||Ok (2024/9/1)
简介:lomefloxacin hydrochloride (okacyn) inhibits dna gyrase, a type ii topoisomerase involved in the induction or relaxation of supercoiling during dna replication. this inhibition leads to a decrease in dna synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. lomefloxacin hydrochloride is the hydrochloride salt form of lomefloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity.
N-(Propargyl-PEG4)-N-bis(PEG4-acid);化合物 T16249N-(Propargyl-PEG4)-N-bis(PEG4-acid) (2024/9/1)
简介:n-(propargyl-peg4)-n-bis(peg4-acid) is a polyethylene glycol (peg)-based linker extensively utilized in the synthesis of protacs (proteolysis targeting chimeras)[1].
N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester);化合物 T16248n-propargyl-peg4-carbonyl-n-bis-peg1- (2024/9/1)
简介:n-(propargyl-peg4-carbonyl)-n-bis(peg1-methyl ester) is a polyethylene glycol (peg) based linker, employed in the synthesis of proteolysis-targeting chimeras (protacs)[1].
N-(Propargyl-PEG4)-biocytin;化合物 T16247N-(Propargyl-PEG4)-biocytin (2024/9/1)
简介:n-(propargyl-peg4)-biocytin is a polyethylene glycol (peg)-based linker designed specifically for the construction of proteolysis targeting chimeras (protacs)[1].
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester;化合物 T16246N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester (2024/9/1)
简介:n-(propargyl-peg2)-n-boc-peg3-t-butyl ester is a polyethylene glycol (peg)-based linker employed for the synthesis of proteolysis-targeting chimeras (protacs) [1].
N-(PEG3-acid)-N-bis(PEG3-amine);化合物 T16245N-(PEG3-acid)-N-bis(PEG3-amine) (2024/9/1)
简介:n-(peg3-acid)-n-bis(peg3-amine) is a polyethylene glycol (peg)-based linker utilized for the synthesis of proteolysis targeting chimeras (protacs)[1].
N-(PEG2-C2-acid)-N-bis(PEG2-propargyl);化合物 T16244N-(PEG2-C2-acid)-N-bis(PEG2-propargyl) (2024/9/1)
简介:n-(peg2-c2-acid)-n-bis(peg2-propargyl) is a polyethylene glycol (peg)-based linker compound designed for the synthesis of protacs[1].
N-(PEG2-Boc)-N-bis(PEG2-propargyl);化合物 T16243N-(PEG2-Boc)-N-bis(PEG2-propargyl) (2024/9/1)
简介:n-(peg2-boc)-n-bis(peg2-propargyl) is a polyethylene glycol (peg)-based protac linker employed for the synthesis of protacs[1].
N-(PEG1-OH)-N-Boc-PEG2-propargyl;化合物 T16242N-(PEG1-OH)-N-Boc-PEG2-propargyl (2024/9/1)
简介:n-(peg1-oh)-n-boc-peg2-propargyl is a polyethylene glycol (peg)-based linker utilized in the synthesis of proteolysis targeting chimeras (protacs)[1].
N-(NHS-PEG3)-N-bis(PEG3-azide);化合物 T16241N-(NHS-PEG3)-N-bis(PEG3-azide) (2024/9/1)
简介:n-(nhs-peg3)-n-bis(peg3-azide) is a polyethylene glycol (peg)-based linker commonly utilized for the synthesis of proteolysis targeting chimeras (protacs)[1].
N,N’-Diacetyl-L-cystine;化合物N,N’-Diacetyl-L-cystine(Ac-Cys-OH)2|||DiNAC;(Ac-Cys-OH)2|||DiNAC (2024/9/1)
简介:n,n´-diacetyl-l-cystine (dinac) is the disulphide dimer of n-acetylcysteine with immunomodulating properties. n,n´-diacetyl-l-cystine also has antiatherosclerotic effects in watanabe-heritable hyperlipidemic rabbit (whhl) rabbits. n,n´-diacetyl-l-cystine is also an effective and orally active modulator of contact sensitivity/delayed-type hypersensitivity reactions in rodents.
N-Methylisatoic anhydride;N-甲基靛红酸酐NMIA;NMIA|||N-甲基靛红酸酐|||1-甲基苯唑 (2024/9/1)
简介:n-methylisatoic anhydride is a 2´-oh selective acylation agent of rnas. it is also widely used for resolving secondary rna structures using the shape technology.
N-Methyl-N-(t-Boc)-PEG4-acid;化合物 T16238N-Methyl-N-(t-Boc)-PEG4-acid (2024/9/1)
简介:n-methyl-n-(t-boc)-peg4-acid is a polyethylene glycol (peg) derivative utilized as a protac linker in the synthesis of protacs, which refers to proteolysis-targeting chimeras[1].
N-Me-N-bis-PEG4;化合物 T16237N-Me-N-bis-PEG4 (2024/9/1)
简介:n-me-n-bis-peg4 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N-Me-N-bis(PEG2-propargyl);化合物 T16236N-Me-N-bis(PEG2-propargyl) (2024/9/1)
简介:n-me-n-bis(peg2-propargyl) is a peg-based linker employed for the synthesis of protacs[1].
N-(Mal-PEG6)-N-bis(PEG3-amine);化合物 T16235N-(Mal-PEG6)-N-bis(PEG3-amine) (2024/9/1)
简介:n-(mal-peg6)-n-bis(peg3-amine) is a polyethylene glycol (peg)-based proteolysis targeting chimera (protac) linker, which is utilized for the synthesis of protacs[1].