9月
NGD-4715；化合物 T16293NGD-4715 (2024/9/1)
简介：ngd-4715 is a selective and orally active antagonist of melanin-concentrating hormone receptor 1.
NFPS；化合物 T16292NFPS (2024/9/1)
简介：nfps exerts neuroprotection via glyr alpha1 subunit in the rat model of transient focal cerebral ischaemia and reperfusion. nfps is a selective and non-competitive glycine transporter-1 (glyt1) inhibitor (ic50s: 2.8 nm and 9.8 nm for hglyt1 and rglyt1, respectively).
NF157；化合物 T16291NF157 (2024/9/1)
简介：nf157 significantly decreases the expression of metalloproteinase (mmp)-3, mmp-13, which can be used in the treatment of osteoarthritis (oa). nf157 is a highly selective nanomolar p2y11 antagonist (pki: 7.35). the ic50s are 463 nm, 1811 μm, 170 μm for p2y11 (ki=44.3 nm), p2y1 (ki=187 μm), p2y2 (ki=28.9 μm), respectively.
NIK SMI1；化合物NIK SMI1NIK SMI1 (2024/9/1)
简介：nik smi1 is an effective and selective nf-κb inducing kinase (nik) inhibitor. it also inhibits nik-catalyzed hydrolysis of atp to adp (ic50: 0.23±0.17 nm).
Rifapentine；利福喷丁MDL473|||Rifapentina|||Rifapentinum|||DL 473|||Priftin|||Cyclopentylrifampicin；MDL47 (2024/9/1)
简介：rifapentine (rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.
Neuropathiazol；化合物NeuropathiazolNeuropathiazol (2024/9/1)
简介：neuropathiazol causes neuronal differentiation of adult hippocampal neural progenitor cells.
Neurodazine；化合物NeurodazineNeurodazine (2024/9/1)
简介：neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.neurodazine promotes differentiation by activating wnt and shh signaling.
Nelonemdaz；化合物 NelonemdazSalfaprodil free base|||Neu2000；Salfaprodil free base|||Neu2000 (2024/9/1)
简介：nelonemdaz (neu2000) is an nmda receptor antagonist with antioxidant activity and neuroprotective activity used in the study of cerebral infarction reperfusion injury and acute ischemic stroke.
Neoseptin 3；化合物 T16284Neoseptin 3 (2024/9/1)
简介：neoseptin 3 is an agonist of toll-like receptor 4/myeloid differentiation factor 2 (ec50: 18.5 μm).
Neocarzinostatin；化合物 T16283Neocarzinostatin (2024/9/1)
简介：neocarzinostatin is an effective dna-damaging, anti-tumor antibiotic. it recognizes double-stranded dna bulge and induces dna double strand breaks (dsbs). neocarzinostatin leads to apoptosis. neocarzinostatin has potential for epcam-positive cancer treatment.
Nelonicline；化合物 T16281ABT-126；ABT-126 (2024/9/1)
简介：nelonicline is a selective agonist of neuronal nicotinic receptors.
Nedocromil尼多克罗FPL 59002|||尼多克罗 (2024/9/1)
简介：nedocromil (fpl 59002) inhibits the action or formation of multiple mediators. which including histamine, leukotriene c4 (ltc4), and prostaglandin d2 (pgd2).
Rivastigmine tartrate；酒石酸卡巴拉汀SDZ-ENA 713|||ENA 713；SDZ-ENA 713|||ENA 713|||酒石酸卡巴拉汀 (2024/9/1)
简介：rivastigmine tartrate (sdz-ena 713) is a carbamate-derived reversible cholinesterase inhibitor that is selective for the central nervous system and is used for the treatment of dementia in alzheimer disease and parkinson disease.
Nebicapone；化合物 T16279BIA 3-202；BIA 3-202 (2024/9/1)
简介：nebicapone is a reversible catechol-o-methyltransferase (comt) inhibitor and is mainly metabolized by glucuronidation. nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of l-dopa to 3-o-methyl-dopa by inhibition of comt. it is the potential for the treatment of parkinson´s disease.
NCX1022；化合物 T16278NCX1022 (2024/9/1)
简介：ncx1022 is a no-releasing derivative of hydrocortisone. it is the most widely used anti-inflammatory drug for the treatment of skin inflammation.
NCT-502；化合物NCT-502N-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbo (2024/9/1)
简介：nct-502 (n-(4,6-dimethylpyridin-2-yl)-4-[5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to phgdh-dependent cancer cells. it decreases glucose-derived serine production and it has an ic50 of 3.7 μm against phgdh.
NBD-556；化合物NBD-556NBD-556 (2024/9/1)
简介：nbd-556 is a small molecule mimetic of cd4. nbd-556 recognizes the hiv-1 envelope protein gp120 and induces restructuring of gp120 analogous to cd4 binding.
NB001；化合物NB001HTS 09836；HTS 09836 (2024/9/1)
简介：nb001 (hts 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.
Napsagatran hydrate；化合物 T16273Ro 46-6240/010 hydrate|||Ro 46-6240 hydrate；Ro 46-6240/010 hydrate|||R (2024/9/1)
简介：napsagatran hydrate is a novel and specific inhibitor of thrombin.
Naproxen etemesil；化合物 T16272LT-NS 001|||MX 1094；LT-NS 001|||MX 1094 (2024/9/1)
简介：naproxen is a cox-1 and cox-2 inhibitor (ic50s: 8.72 and 5.15 μm, respectively in cell assay). naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. it is hydrolyzed to pharmacologically active naproxen once absorbed.
Napropamide敌草胺敌草胺|||Napropamid (2024/9/1)
简介：napropamide is a selective systemic amide herbicide. napropamide is used to control a number of annual grasses and broad-leaved weeds.
Nanatinostat；化合物 T16270CHR-3996；CHR-3996 (2024/9/1)
简介：nanatinostat is an effective and class i selective inhibitor of histone deacetylase (ic50: 8 nm).
Famotidine；法莫替丁MK-208；MK-208|||法莫替丁 (2024/9/1)
简介：famotidine (mk-208) is a propanimidamide and histamine h2-receptor antagonist with antacid activity. as a competitive inhibitor of histamine h2-receptors located on the basolateral membrane of the parietal cell, famotidine reduces basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to various stimuli.
Nanaomycin A；化合物Nanaomycin ANanaomycin A (2024/9/1)
简介：nanaomycin a, a quinone antibiotics, reactivates silenced tumor suppressor genes in human cancer cells. nanaomycin a is a selective inhibitor of dnmt3b (ic50 = 500 nm).
Namitecan；化合物 T16268ST-1968；ST-1968 (2024/9/1)
简介：namitecan is an effective inhibitor of topoisomerase i. it has antitumor property.
Naminidil化合物 T16267BMS 234303-01 (2024/9/1)
简介：naminidil is an opener of cyanoguanidine katp.
NAMI-A；化合物NAMI-ANAMI-A (2024/9/1)
简介：nami-a is a ruthenium-based compound with selective activity against tumor metastasis.nami-a inhibits cancer cell adhesion and migration.
Naluzotan；那鲁佐坦PRX 00023；PRX 00023 (2024/9/1)
简介：naluzotan（prx 00023） is a novel and potent 5-ht1a agonist with ic50 and ki values of approximately 20 nm and 5.1 nm, respectively.naluzotan is a potent herg k+ channel blocker with an ic50 value of 3800 nm.naluzotan exhibits anxiolytic activity and can be used to study depression.
Nagilactone B；竹柏内酯 BNagilactone B (2024/9/1)
简介：nagilactone b is extracted from the root bark of podocarpus nagi and it also is a liver x receptor (lxr) agonist.
N6-Cyclopentyladenosine；N6-环戊基腺苷酸UK-80882|||CPA；UK-80882|||CPA (2024/9/1)
简介：n6-cyclopentyladenosine (cpa) is a selective agonist of the adenosine a1 receptor and can be used to mimic the action of the adenosine a1 receptor, with ki´s of 2.3 nm, 790 nm, and 43 nm for human a1, a2a, and a3 receptors, respectively.n6-cyclopentyladenosine (cpa) can be used to modulate cellular signaling and neurotransmission and other biological processes. cyclopentyladenosine (cpa) is used to regulate cell signaling, neurotransmitter release and other biological processes.
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