9月
Nitisinone；尼替西农NTBC|||SC0735|||Nitisone；尼替西农|||NTBC|||SC0735|||Nitisone (2024/9/1)
简介：nitisinone (sc0735)(sc0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor.
sAJM589；化合物 T16839sAJM589 (2024/9/1)
简介：sajm589 is a myc inhibitor(ic50: 1.8 μm).
Saikogenin A；柴胡皂苷元ASaikogenin A (2024/9/1)
简介：saikogenin a is a dipeptidyl peptidase-4 inhibitor.
SAICAR；化合物 T16837SAICAR (2024/9/1)
简介：saicar is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform m2 (pkm2) in an isozyme-selective manner (ec50: 0.3 mm).
SAFit2；化合物SAFit2SAFit2 (2024/9/1)
简介：safit2 is a highly effective and selective fk506 binding protein 51(fkbp51) inhibitor (ki: 6 nm). safit2 can enhance akt2-as160 binding and participate in the downstream response of glucocorticoid release in vivo, and is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.
SAFit1；化合物 T16835SAFit1 (2024/9/1)
简介：safit1 is an inhibitor of fk506 binding protein 51 (fkbp51)-specific (ki: 4±0.3 nm).
S1P1 Agonist III；化合物 T16833S1P1 Agonist III (2024/9/1)
简介：s1p1 agonist iii is an effective and orally active s1p1 agonist (ec50: 18 nm).
S18-000003；化合物S18-000003S18-000003 (2024/9/1)
简介：s18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (ic50: 29 nm). s18-000003 inhibits il-17 production.
(S)-SNAP5114；化合物(S)-SNAP5114(S)-SNAP5114 (2024/9/1)
简介：(s)-snap5114 is a selective inhibitor of gaba transport with ic50s of 5 μm for hgat-3 and 21 μm for rgat-2. (s)-snap5114 has anticonvulsant properties.
S-MTC；化合物 T16830S-MTC (2024/9/1)
简介：s-mtc is a selective inhibitor of type i nitric oxide synthase.
Actriol；异雌三醇Epiestriol；异雌三醇|||Epiestriol (2024/9/1)
简介：actriol (epiestriol) is always used as glucocorticoid receptor agonist.
(S)-BI-1001；化合物 T16829(S)-BI-1001 (2024/9/1)
简介：(s)-bi-1001 is an active s-enantiomer of bi-1001. (s)-bi-1001 has antiviral potency against hiv-1 integrase (ic50: 28 nm, and ec50: 450 nm and a kd: 4.7 μm).
S-Acetyl-PEG8-OH；化合物 T16828S-Acetyl-PEG8-OH (2024/9/1)
简介：s-acetyl-peg8-oh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-acetyl-PEG6-Tos；化合物 T16827S-acetyl-PEG6-Tos (2024/9/1)
简介：s-acetyl-peg6-tos is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-acetyl-PEG6-Boc；化合物 T16826S-acetyl-PEG6-Boc (2024/9/1)
简介：s-acetyl-peg6-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-acetyl-PEG4-propargyl；化合物 T16825S-acetyl-PEG4-propargyl (2024/9/1)
简介：s-acetyl-peg4-propargyl is a peg-based protac linker employed for synthesizing protacs[1].
S-acetyl-PEG4-Boc；化合物 T16824S-acetyl-PEG4-Boc (2024/9/1)
简介：s-acetyl-peg4-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-acetyl-PEG4-alcohol；化合物 T16823S-acetyl-PEG4-alcohol (2024/9/1)
简介：s-acetyl-peg4-alcohol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-Acetyl-PEG3-C2-acid；化合物 T16822S-Acetyl-PEG3-C2-acid (2024/9/1)
简介：s-acetyl-peg3-c2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-acetyl-PEG3-Boc；化合物 T16821S-acetyl-PEG3-Boc (2024/9/1)
简介：s-acetyl-peg3-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-Acetyl-PEG3-azide；化合物 T16820S-Acetyl-PEG3-azide (2024/9/1)
简介：s-acetyl-peg3-azide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Methacholine Chloride；醋甲胆碱Mecholyl chloride|||Acetyl-β-methylcholine chloride；醋甲胆碱|||Mecholyl chlori (2024/9/1)
简介：methacholine chloride (acetyl-β-methylcholine chloride) is a quaternary ammonium parasympathomimetic agent with the muscarinic actions of acetylcholine. it is hydrolyzed by acetylcholinesterase at a considerably slower rate than acetylcholine and is more resistant to hydrolysis by nonspecific cholinesterases so that its actions are more prolonged. it is used as a parasympathomimetic bronchoconstrictor agent and as a diagnostic aid for bronchial asthma.
S-acetyl-PEG3-alcohol；化合物 T16819S-acetyl-PEG3-alcohol (2024/9/1)
简介：s-acetyl-peg3-alcohol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
S-8921；化合物 T16818S-8921 (2024/9/1)
简介：s-8921 is an inhibitor of ileal na+/bile acid cotransporter.
S-2474；化合物 S-2474S-2474 (2024/9/1)
简介：s-2474, an inhibitor of cox-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities and inhibits abeta (25 - 35) and abeta (1 - 40) induced cell death.
S 18986；化合物S 18986S 18986 (2024/9/1)
简介：s 18986 is a selective, orally active, brain penetrant positive allosteric modulator of ampa-type receptors, showcasing cognitive-enhancing properties in rodents. it induces the release of noradrenaline and acetylcholine in the rat hippocampus, leading to enhanced object-recognition memory.
RY796；化合物 T16815RY796 (2024/9/1)
简介：ry796 is an effective and selective inhibitor of voltage-gated potassium channel (ic50s: 0.25 μm and 0.09 μm for kv2.1 and kv2.2).
RX 67668；化合物 T16814RX 67668 (2024/9/1)
简介：rx 67668 is a muscle relaxant used to relieve skeletal muscle fatigue. rx 67668 is an effective cholinesterase inhibitor (ic50: 5 μm for both acetylcholinesterase and butyrylcholinesterase). rx 67668 can reverse the neuromuscular blockade induced by d-tubocurarine.
RX-3117；化合物RX-3117fluorocyclopentenylcytosine|||TV-1360；fluorocyclopentenylcytosine|||TV-1360 (2024/9/1)
简介：rx-3117 (fluorocyclopentenylcytosine) is a novel a cytidine analog. rx-3117 displays anticancer activity in several cancer cell lines, including gemcitabine-resistant variants.
RWJ-67657；化合物RWJ-67657JNJ 3026582；JNJ 3026582 (2024/9/1)
简介：rwj-67657 (jnj 3026582) is an orally active and selective p38α and p38β mapk inhibitor (ic50s: 1 and 11 μm, respectively). rwj-67657 shows no activity at p38γ and p38δ and shows a cardioprotective effect.
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