Tr-PEG5-OH;化合物 T17152Tr-PEG5-OH (2024/9/1)
简介:tr-peg5-oh is a non-cleavable 5 unit peg adc linker used in the synthesis of antibody-drug conjugates (adcs).
Tr-PEG4-OH;化合物 T17151Tr-PEG4-OH (2024/9/1)
简介:tr-peg4-oh is a non-cleavable tetraethylene glycol adc linker employed in adc synthesis for the conjugation of antibodies and drugs.
Tr-PEG3-OH;化合物 T17150Tr-PEG3-OH (2024/9/1)
简介:tr-peg3-oh is a non-cleavable, three-unit peg adc linker employed for adc synthesis, specifically in the context of antibody-drug conjugates (adcs).
Chitosan (MW 150000);壳聚糖Chitosan|||Poly(D-glucosamine)|||Deacetylated chitin;壳聚糖|||Chitosan|||Poly(D (2024/9/1)
简介:chitosan (mw 150000) (deacetylated chitin) is a linear polysaccharide composed of randomly distributed β-(1-4)-linked d-glucosamine (deacetylated unit) and n-acetyl-d-glucosamine.
Tr-PEG2-OH;化合物 T17149Tr-PEG2-OH (2024/9/1)
简介:tr-peg2-oh is a peg-based protac linker utilized in protac synthesis[1]. it also serves as a non-cleavable 2-unit peg adc linker for the synthesis of antibody-drug conjugates (adcs)[2].
TPPB;化合物TPPBTPPB (2024/9/1)
简介:tppb is a kinase c activator of cell-permeable benzolactam-derived protein (ki: 11.9 nm).
TPOP146化合物 T17147TPOP 146|||TPOP-146|||TPOP146 (2024/9/1)
简介:tpop146 is a selective cbp/p300 benzoxazepine bromodomain inhibitor (kd: 134 nm and 5.02 μm for cbp and brd4).
TPO agonist 1;化合物 T17146TPO agonist 1 (2024/9/1)
简介:tpo agonist 1 is a thrombopoietin agonist. it would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia.
Tpl2 Kinase Inhibitor 1;化合物 T17145Tpl2 Kinase Inhibitor 1 (2024/9/1)
简介:tpl2 kinase inhibitor 1 is an effective and selective tpl2 inhibitor.
TPA 023;化合物TPA 023TPA 023 (2024/9/1)
简介:tpa 023 is a selective agonist of gabaa α2/α3 subtype (kis = 0.19 - 0.41 nm).
Toyocamycin;丰加霉素Vengicide;丰加霉素|||Vengicide (2024/9/1)
简介:toyocamycin (vengicide) is an adenosine analog produced by actinomycete, acts as an xbp1 inhibitor, inhibits ire1α-induced atp-dependent xbp1 mrna cleavage (ic50: 80 nm). toyocamycin induces apoptosis.
Toxoflavin;毒黄素Xanthothricin|||PKF-118-310|||Toxoflavine;毒黄素|||Xanthothricin|||PKF-118-310|||Toxoflav (2024/9/1)
简介:toxoflavin (xanthothricin) is an antagonist of transcription factor 4 (tcf4)/β-catenin complex. toxoflavin also acts as an inhibitor of kdm4a.
Tos-PEG9;化合物 T17141Tos-PEG9 (2024/9/1)
简介:tos-peg9 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG9-Boc;化合物 T17140Tos-PEG9-Boc (2024/9/1)
简介:tos-peg9-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG7-OH;化合物 T17139Tos-PEG7-OH (2024/9/1)
简介:tos-peg7-oh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG6-OH;化合物 T17138Tos-PEG6-OH (2024/9/1)
简介:tos-peg6-oh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG6-CH2-Boc;化合物 T17137Tos-PEG6-CH2-Boc (2024/9/1)
简介:tos-peg6-ch2-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG6-C2-Boc;化合物 T17136Tos-PEG6-C2-Boc (2024/9/1)
简介:tos-peg6-c2-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG5-CH2COOtBu;化合物 T17135Tos-PEG5-CH2COOtBu (2024/9/1)
简介:tos-peg5-ch2cootbu is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG5-C2-Boc;化合物 T17134Tos-PEG5-C2-Boc (2024/9/1)
简介:tos-peg5-c2-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG4-t-butyl ester;化合物 T17133Tos-PEG4-Boc;Tos-PEG4-Boc (2024/9/1)
简介:tos-peg4-t-butyl ester (tos-peg4-boc) is a protac linker characterized by its peg composition. this compound plays a crucial role in the synthesis of a range of protacs, including bi-3663, a highly selective ptk2/fak protac. it employs cereblon ligands to target e3 ligases for the degradation of ptk2, exhibiting potent inhibitory activity with an ic50 of 18 nm[1].
Tos-PEG4-CH2COOH;化合物 T17132Tos-PEG4-CH2COOH (2024/9/1)
简介:tos-peg4-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG4-CH2-Boc;化合物 T17131Tos-PEG4-CH2-Boc (2024/9/1)
简介:tos-peg4-ch2-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG5-Boc;化合物 T17130Tos-PEG5-Boc (2024/9/1)
简介:tos-peg5-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
IBMXIBMX,3-异丁基-1-甲基黄嘌呤IBMX,3-异丁基-1-甲基黄嘌呤|||3-Isobutyl-1-methylxanthine|||1-Methyl-3-Isobutylxanthine (2024/9/1)
简介:ibmx (methylisobutylxanthine) is a broad-spectrum phosphodiesterase (pde) inhibitor with inhibitory activity against pde3, pde4, and pde5 (ic50=6.5/26.3/31.7 μm). ibmx enhances the intracellular camp level.
Tos-PEG3;化合物 T17129Tos-PEG3 (2024/9/1)
简介:tos-peg3, a peg-based protac linker, is suitable for synthesizing protacs and 3´-aminooxy oligonucleotide solid supports[1].
Tos-PEG3-CH2COOH;化合物 T17128Tos-PEG3-CH2COOH (2024/9/1)
简介:tos-peg3-ch2cooh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG3-C2-methyl ester;化合物 T17127Tos-PEG3-C2-methyl ester (2024/9/1)
简介:tos-peg3-c2-methyl ester is a polyethylene glycol (peg)-based linker utilized for the synthesis of proteolysis targeting chimeras (protacs)[1].
Tos-PEG4-acid;化合物 T17126Tos-PEG4-acid (2024/9/1)
简介:tos-peg4-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tos-PEG2-O-Propargyl;化合物 T17125Tos-PEG2-O-Propargyl (2024/9/1)
简介:tos-peg2-o-propargyl is a polyethylene glycol (peg)-based proteolysis targeting chimera (protac) linker, commonly employed for the synthesis of thalidomide-o-peg2-propargyl[1].