DBCO-PEG4-Desthiobiotin;化合物 T17796DBCO-PEG4-Desthiobiotin (2024/9/1)
简介:dbco-peg4-desthiobiotin is a polyethylene glycol (peg) derivative utilized as a linker for the synthesis of proteolysis-targeting chimeras (protacs)[1].
DBCO-PEG4-alkyne;化合物 T17795DBCO-PEG4-alkyne (2024/9/1)
简介:dbco-peg4-alkyne is a four-unit peg linker with non-cleavable properties, specifically designed for the synthesis of antibody-drug conjugates (adcs)[1].
DBCO-PEG4-alcohol;化合物 T17794DBCO-PEG4-alcohol (2024/9/1)
简介:dbco-peg4-alcohol is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG4-Ahx-DM1;化合物 T17793DBCO-PEG4-Ahx-DM1 (2024/9/1)
简介:dbco-peg4-ahx-dm1 is a drug-linker conjugate that combines the microtubulin inhibitor dm1 (mertansine), which is an antibody-conjugatable maytansinoid designed to reduce systemic toxicity and improve tumor-specific delivery, with the linker dbco-peg4-ahx, for the development of antibody drug conjugates (adcs).
DBCO-PEG3-TCO;化合物 T17792DBCO-PEG3-TCO (2024/9/1)
简介:dbco-peg3-tco is a non-cleavable three-unit polyethylene glycol (peg) linker employed for synthesizing antibody-drug conjugates (adcs)[1].
英国雷尼绍M2三坐标测针 (2024/9/1)
简介:红宝石是一种ji为坚硬的材料,因此测球的磨损甚微。它还具有较低密度,使测尖的质量min,从而避免了因设备运行或振动而引起测头的误触发。
DBCO-PEG3-NHS ester;DBCO-PEG3-NHS酯DBCO-PEG3-NHS ester (2024/9/1)
简介:dbco-peg3-nhs ester is a degradable adc linker that can be used to synthesize antibody-coupled active molecules.
DBCO-PEG3-oxyamine;化合物 T17790DBCO-PEG3-oxyamine (2024/9/1)
简介:dbco-peg3-oxyamine is a non-cleavable 3-unit polyethylene glycol linker employed for the synthesis of antibody-drug conjugates (adcs)[1].
SAG;化合物Smoothened AgonistSmoothened Agonist (SAG) HCl|||Smoothened Agonist;Smoothened Agonist (SAG) (2024/9/1)
简介:sag (smoothened agonist) is a smo receptor agonist (ec50=3 nm) that is cell-permeable and selective. sag regulates smo activity by binding directly to the smo helix and can activate the hedgehog signaling pathway.
DBCO-(PEG2-VC-PAB-MMAE)2;化合物 T17789DBCO-(PEG-2-VC-PAB-MMAE)2|||DBCO(PEG2VCPABMMAE)2|||DBCO-(PEG2-VC- (2024/9/1)
简介:dbco-(peg2-vc-pab-mmae)2 consists of monomethyl auristatin e (mmae), a toxin payload in antibody-drug conjugate [1], conjugated to the cleavable linker dbco-(peg2-vc-pab)2. mmae, a potent tubulin inhibitor, serves as the cytotoxic component in this formulation.
DBCO-(PEG2-Val-Cit-PAB)2;化合物 T17788DBCO-(PEG2-Val-Cit-PAB)2 (2024/9/1)
简介:dbco-(peg2-val-cit-pab)2 is a dual cleavable adc linker for antibody-drug conjugates (adcs).
英国雷尼绍M2三坐标测针 (2024/9/1)
简介:红宝石是一种ji为坚硬的材料,因此测球的磨损甚微。它还具有较低密度,使测尖的质量min,从而避免了因设备运行或振动而引起测头的误触发。
DBCO-PEG2-NH-Boc;化合物 T17787DBCO-PEG2-NH-Boc (2024/9/1)
简介:dbco-peg2-nh-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG2-amine;化合物 T17786DBCO-PEG2-amine (2024/9/1)
简介:dbco-peg2-amine is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG2-acid;化合物 T17785DBCO-PEG2-acid (2024/9/1)
简介:dbco-peg2-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG13-DBCO;化合物 T17784DBCO-PEG13-DBCO (2024/9/1)
简介:dbco-peg13-dbco is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG12-NHS ester;化合物 T17783DBCO-PEG12-NHS ester (2024/9/1)
简介:dbco-peg12-nhs ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG12-acid;化合物 T17782DBCO-PEG12-acid (2024/9/1)
简介:dbco-peg12-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG10-DBCO;化合物 T17781DBCO-PEG10-DBCO (2024/9/1)
简介:dbco-peg10-dbco is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG1;化合物 T17780DBCO-PEG1 (2024/9/1)
简介:dbco-peg1 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
英国雷尼绍M2三坐标测针 (2024/9/1)
简介:红宝石是一种ji为坚硬的材料,因此测球的磨损甚微。它还具有较低密度,使测尖的质量min,从而避免了因设备运行或振动而引起测头的误触发。
AT7519 Hydrochloride;化合物AT 7519 hydrochloride saltAT7519 HCl|||AT 7519 hydrochloride salt;AT7519 HCl (2024/9/1)
简介:at7519 hydrochloride (at7519 hcl) is a multi-cdk inhibitor for cdk1, 2, 4, 6 and 9.
DBCO-PEG1-NHS ester;化合物 T17779DBCO-PEG1-NHS ester (2024/9/1)
简介:dbco-peg1-nhs ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
英国雷尼绍M2三坐标测针 (2024/9/1)
简介:红宝石是一种ji为坚硬的材料,因此测球的磨损甚微。它还具有较低密度,使测尖的质量min,从而避免了因设备运行或振动而引起测头的误触发。
DBCO-PEG1-NH-Boc;化合物 T17778DBCO-PEG1-NH-Boc (2024/9/1)
简介:dbco-peg1-nh-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG1-amine;化合物 T17777DBCO-PEG1-amine (2024/9/1)
简介:dbco-peg1-amine is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DBCO-PEG1-acid;化合物 T17776DBCO-PEG1-acid (2024/9/1)
简介:dbco-peg1-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
英国雷尼绍M2三坐标测针 (2024/9/1)
简介:红宝石是一种ji为坚硬的材料,因此测球的磨损甚微。它还具有较低密度,使测尖的质量min,从而避免了因设备运行或振动而引起测头的误触发。
DBCO-NHS ester 3;化合物 T17775DBCO-NHS ester 3 (2024/9/1)
简介:dbco-nhs ester 3 (compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (adc). it is a derivative of dibenzylcyclooctyne (dbco) resulting from the activation of n-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (meond) and dibenzoazacyclooctyne (dibac)[1][2].
DBCO-NHCO-S-S-NHS ester;化合物 T17774DBCO-NHCO-S-S-NHS ester (2024/9/1)
简介:dbco-nhco-s-s-nhs ester is a cleavable linker employed for the synthesis of antibody-drug conjugates (adcs)[1].