9月
Bromoacetyl-PEG3-DBCO；化合物 T17705Bromoacetyl-PEG3-DBCO (2024/9/1)
简介：bromoacetyl-peg3-dbco is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bromoacetamido-PEG9-ethylcarbamoyl-C8-Boc；化合物 T17704Bromoacetamido-PEG9-ethylcarbamoyl-C8-Boc (2024/9/1)
简介：bromoacetamido-peg9-ethylcarbamoyl-c8-boc represents a peg-based protac linker suitable for synthesizing protacs[1].
Bromoacetamido-PEG9-ethylcarbamoyl-C4-Boc；化合物 T17703Bromoacetamido-PEG9-ethylcarbamoyl-C4-Boc (2024/9/1)
简介：bromoacetamido-peg9-ethylcarbamoyl-c4-boc is a polyethylene glycol (peg)-based proteolysis targeting chimera (protac) linker, used for synthesizing protacs[1].
Bromoacetamido-PEG9-ethylcarbamoyl-C12-Boc；化合物 T17702Bromoacetamido-PEG9-ethylcarbamoyl-C12-Boc (2024/9/1)
简介：bromoacetamido-peg9-ethylcarbamoyl-c12-boc is a polyethylene glycol (peg) derived linker employed for synthesizing proteolysis-targeting chimeras (protacs)[1].
Bromoacetamido-PEG5-DOTA；化合物 T17701Bromoacetamido-PEG5-DOTA (2024/9/1)
简介：bromoacetamido-peg5-dota is a peg-derived linker compound utilized for the synthesis of protacs[1].
Bromoacetamide-PEG3-propargyl；化合物 T17700Bromoacetamide-PEG3-propargyl (2024/9/1)
简介：bromoacetamide-peg3-propargyl is a polyethylene glycol (peg) derived linker utilized for the synthesis of proteolysis targeting chimeras (protacs)[1].
GNE-9605；化合物GNE9605GNE-9605 (2024/9/1)
简介：gne-9605 is a highly effective, specifical, and brain-penetrant lrrk2 inhibitor (ic50: 19 nm).
Bromo-PEG24-Boc；化合物 T17699Bromo-PEG24-Boc (2024/9/1)
简介：bromo-peg24-boc is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bromo-PEG1-C2-azide；化合物Bromo-PEG1-C2-azideBromo-PEG1-C2-azide (2024/9/1)
简介：bromo-peg1-c2-azide is a peg-based protac linker that can be used in protac synthesis.
BRD7-IN-1；化合物BRD7-IN-1BRD7-IN-1 (2024/9/1)
简介：brd7-in-1, a modified derivative of bi7273 (brd7/9 inhibitor), forms protac vz185 through linkage to a vhl ligand, demonstrating potent activity against brd7/9 with dc50 values of 4.5 and 1.8 nm, respectively [1].
BRD7-IN-1 free base；化合物 T17696BRD7-IN-1 free base (2024/9/1)
简介：brd7-in-1 free base, a modified derivative of bi7273 (brd7/9 inhibitor), interacts with a vhl ligand through a linker, constituting the protac vz185 (targeting brd7/9 with dc50 values of 4.5 and 1.8 nm, respectively)[1].
Br-PEG7-Br溴代-八聚乙二醇-溴代溴代-八聚乙二醇-溴代 (2024/9/1)
简介：br-peg7-br is a peg-based protac linker that can be used in protac synthesis.
Br-C10-methyl ester11-溴代十一烷酸甲酯11-溴代十一烷酸甲酯 (2024/9/1)
简介：br-c10-methyl ester, a protac linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of protacs (ms432). this compound incorporates a dual-ligand system connected via a linker; notably, one ligand interacts with the vhl portion.
Boc-Val-Cit-PAB；化合物Boc-Val-Cit-PABBoc-Val-Cit-PAB (2024/9/1)
简介：boc-val-cit-pab is a cleavable adc linker. boc-val-cit-pab used in the synthesis of antibody-drug conjugates (adcs).
英国雷尼绍M2三坐标测针 (2024/9/1)
简介：红宝石是一种ji为坚硬的材料，因此测球的磨损甚微。它还具有较低密度，使测尖的质量min，从而避免了因设备运行或振动而引起测头的误触发。
Boc-Val-Cit-PAB-PNP；化合物Boc-Val-Cit-PAB-PNPinhibit|||Antibody-drug conjugates linkers|||BocValCitPABP (2024/9/1)
简介：boc-val-cit-pab-pnp is a cleavable adc linker used in antibody-drug conjugates (adcs) synthesis.
Boc-Val-Cit-OH；化合物Boc-Val-Cit-OHBoc-Val-Cit-OH (2024/9/1)
简介：boc-val-cit-oh is a cleavable adc linker used in antibody-drug conjugates (adcs) synthesis.
Boc-Val-Ala-PAB-PNP；化合物 T17690Boc Val Ala PAB PNP|||Boc-Val-Ala-PAB-PNP|||BocValAlaPABPNP；Boc Val Al (2024/9/1)
简介：boc-val-ala-pab-pnp is an adc linker employed for the synthesis of antibody-drug conjugates (adcs)[1]. this cleavable compound efficiently facilitates the attachment of drugs to antibodies, allowing for targeted delivery and release of therapeutic agents within the body, making it an important component in adc development.
Pardoprunox；帕多芦诺SLV-308|||DU-126891；帕多芦诺|||SLV-308|||DU-126891 (2024/9/1)
简介：pardoprunox (slv-308) is a partial dopamine d2 agonist and noradrenergic agonist with serotonin 5-ht1a agonist properties. pardoprunox has been used in trials studying the treatment of early stage parkinson´s disease and advanced stage parkinson´s disease.
Boc-Pip-alkyne-Ph-COOH；化合物 T17689Boc-Pip-alkyne-Ph-COOH (2024/9/1)
简介：boc-pip-alkyne-ph-cooh, a protac linker characterized by its alkyl/ether composition, plays a crucial role in synthesizing protacs including ard-266. this compound demonstrates significant efficacy in promoting the degradation of androgen receptor (ar) protein across ar-positive prostate cancer cell lines such as lncap, vcap, and 22rv1, showcasing dc50 values ranging from 0.2-1 nm[1].
Boc-Phe-(Alloc)Lys-PAB-PNP；化合物 T17688Boc-Phe-(Alloc)Lys-PAB-PNP|||BocPhe(Alloc)LysPABPNP|||Boc Phe ( (2024/9/1)
简介：boc-phe-(alloc)lys-pab-pnp serves as a cleavable linker in the synthesis of antibody-drug conjugates (adcs).
Boc-PEG4-sulfone-PEG4-Boc；化合物 T17687Boc-PEG4-sulfone-PEG4-Boc (2024/9/1)
简介：boc-peg4-sulfone-peg4-boc is a polyethylene glycol (peg)-derived linker specifically designed for the synthesis of proteolysis-targeting chimeras (protacs)[1].
Boc-PEG4-C2-NHS ester；化合物 T17686Boc-PEG4-C2-NHS ester (2024/9/1)
简介：boc-peg4-c2-nhs ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-NH-PEG9-propargyl；化合物 T17685Boc-NH-PEG9-propargyl (2024/9/1)
简介：boc-nh-peg9-propargyl is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-NH-PEG8-CH2CH2NH2叔丁氧羰基八聚乙二醇胺叔丁氧羰基八聚乙二醇胺 (2024/9/1)
简介：boc-nh-peg8-ch2ch2nh2 is a peg-based protac linker that can be used in protac synthesis.
Boc-NH-PEG8-CH2CH2COOHN-叔丁氧羰基-七聚乙二醇-羧酸N-叔丁氧羰基-七聚乙二醇-羧酸 (2024/9/1)
简介：boc-nh-peg8-ch2ch2cooh is a peg-based protac linker that can be used in protac synthesis.
Boc-NH-PEG7-Tos；化合物Boc-NH-PEG7-Tost-Boc-N-Amido-PEG7-Tos；t-Boc-N-Amido-PEG7-Tos (2024/9/1)
简介：boc-nh-peg7-tos (t-boc-n-amido-peg7-tos) is a peg-based protac linker that can be used in protac synthesis.
Boc-NH-PEG6-CH2COOH叔丁氧羰基六聚乙二醇乙酸叔丁氧羰基六聚乙二醇乙酸 (2024/9/1)
简介：boc-nh-peg6-ch2cooh is a peg-based protac linker that can be used in protac synthesis.
Boc-NH-PEG4-Ms；化合物 T17680Boc-NH-PEG4-Ms (2024/9/1)
简介：boc-nh-peg4-ms is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
7ACC2；化合物7ACC27ACC2 (2024/9/1)
简介：7acc2 is a new potent mct inhibitor with ic50 of 11 nm for [14c]-lactate influx; new antitumor treatment targeting lactate transport in y cells.
MSN交谈
