ZM 306416;化合物ZM 306416CB 676475;CB 676475 (2024/9/1)
简介:zm 306416 (cb 676475), a vegfr1 inhibitor (ic50: 0.33 μm), can also inhibit egfr (ic50<10 nm).
BCN-SS-amine;化合物 T17539BCN-SS-amine (2024/9/1)
简介:bcn-ss-amine is a cleavable linker vital in adc synthesis. bcn-ss-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. the cleavable nature ensures controlled drug release, optimizing adc effectiveness.
BCN-PEG4-Ts;化合物 T17538BCN-PEG4-Ts (2024/9/1)
简介:bcn-peg4-ts is a four-unit polyethylene glycol (peg) linker, which is non-cleavable. it finds application in the synthesis of antibody-drug conjugates (adcs)[1].
BCN-PEG4-OH;化合物 T17537BCN-PEG4-OH (2024/9/1)
简介:bcn-peg4-oh is a non-cleavable 4-unit peg linker essential for synthesizing antibody-drug conjugates (adcs)[1].
BCN-PEG4-NHS ester;化合物 T17536BCN-PEG4-NHS ester (2024/9/1)
简介:bcn-peg4-nhs ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
BCN-PEG4-hydrazide;化合物 T17535BCN-PEG4-hydrazide (2024/9/1)
简介:bcn-peg4-hydrazide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
BCN-PEG4-alkyne;化合物 T17534BCN-PEG4-alkyne (2024/9/1)
简介:bcn-peg4-alkyne is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
BCN-PEG4-acid;化合物 T17533BCN-PEG4-acid (2024/9/1)
简介:bcn-peg4-acid is a cleavable four-unit polyethylene glycol (peg) linker employed in the synthesis of antibody-drug conjugates (adcs)[1].
BCN-PEG3-VC-PFP ester;化合物 T17532BCN-PEG3-VC-PFP ester (2024/9/1)
简介:bcn-peg3-vc-pfp ester is a three-unit peg adc linker that can be cleaved, and it is commonly employed in the synthesis of antibody-drug conjugates (adcs) [1].
BCN-PEG3-Val-Cit;化合物 T17531BCN-PEG3-Val-Cit (2024/9/1)
简介:bcn-peg3-val-cit is a peg-based linker commonly employed in protac synthesis[1]. additionally, it serves as a cleavable 3 unit peg linker in the production of antibody-drug conjugates (adcs)[2].
BCN-PEG3-oxyamine;化合物 T17530BCN-PEG3-oxyamine (2024/9/1)
简介:bcn-peg3-oxyamine is a non-cleavable three-unit polyethylene glycol linker employed in the synthesis of antibody-drug conjugates (adcs)[1].
D-64131;化合物D64131D-64131 (2024/9/1)
简介:d-64131 is a tubulin polymerization inhibitor with an ic50 value of 0.53 μm.
BCN-PEG3-Biotin;化合物 T17529BCN-PEG3-Biotin (2024/9/1)
简介:bcn-peg3-biotin is a non-cleavable three-unit peg linker employed in the synthesis of antibody-drug conjugates (adcs)[1].
BCN-PEG1-Val-Cit-PABC-OH;化合物 T17528BCN-PEG1-Val-Cit-PABC-OH (2024/9/1)
简介:bcn-peg1-val-cit-pabc-oh is a cleavable 1-unit peg linker specifically utilized in the synthesis of antibody-drug conjugates (adcs)[1].
BCN-PEG1-Val-Cit-OH;化合物 T17527BCN-PEG1-Val-Cit-OH (2024/9/1)
简介:bcn-peg1-val-cit-oh is a cleavable one-unit polyethylene glycol (peg) linker employed in the synthesis of antibody-drug conjugates (adcs) [1].
BCN-exo-PEG3-NH2;化合物 T17526BCN-exo-PEG3-NH2 (2024/9/1)
简介:bcn- exo- peg3- nh2 is a peg-based protac linker that can be used in the synthesis of protacs[1].
Azidoethyl-SS-propionic NHS ester;化合物 T17525Azidoethyl-SS-propionic NHS ester (2024/9/1)
简介:azidoethyl-ss-propionic nhs ester is a cleavable linker frequently employed in the synthesis of antibody-drug conjugates (adcs) [1].
Azidoethyl-SS-propionic acid;化合物 T17524Azidoethyl-SS-propionic acid (2024/9/1)
简介:azidoethyl-ss-propionic acid is an adc linker, specifically designed for the synthesis of antibody-drug conjugates (adcs)[1]. it possesses cleavable properties, allowing for the controlled release of drug payloads.
Azido-PEG9-NHS ester;化合物 T17523Azido-PEG9-NHS ester (2024/9/1)
简介:azido-peg9-nhs ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG9-azide;化合物Azido-PEG9-azideAzido-PEG9-azide (2024/9/1)
简介:azido-peg9-azide is a peg-based protac linker that can be used in protac synthesis.
Azido-PEG9-alcohol叠氮-九聚乙二醇叠氮-九聚乙二醇 (2024/9/1)
简介:azido-peg9-alcohol is a peg-based protac linker that can be used in protac synthesis.
Azido-PEG8-hydrazide;化合物 T17520Azido-PEG8-hydrazide (2024/9/1)
简介:azido-peg8-hydrazide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
NS6180;化合物NS6180NS6180 (2024/9/1)
简介:ns6180 is a potent and selective kca3.1 channel inhibitor(ic50= 9 nm). it prevents t-cell activation and inflammation.
Azido-PEG7-azide;化合物 T17519Azido-PEG7-azide (2024/9/1)
简介:azido-peg7-azide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG6-azide;化合物 T17518Azido-PEG6-azide (2024/9/1)
简介:azido-peg6-azide is a peg-based protac linker that can be used in the synthesis of protacs[1].
Azido-PEG5-triethoxysilane;化合物 T17517Azido-PEG5-triethoxysilane (2024/9/1)
简介:azido-peg5-triethoxysilane serves as a peg-based protac linker for the synthesis of protacs[1].
Azido-PEG5-maleimide;化合物 T17516Azido-PEG5-maleimide (2024/9/1)
简介:azido-peg5-maleimide is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG5-azide叠氮-五聚乙二醇-叠氮叠氮-五聚乙二醇-叠氮 (2024/9/1)
简介:azido-peg5-azide is a peg-based protac linker that can be used in protac synthesis.
Azido-PEG4-nitrile;化合物 T17514Azido-PEG4-nitrile (2024/9/1)
简介:azido-peg4-nitrile is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Azido-PEG4-amido-PEG4-Boc;化合物 T17513Azido-PEG4-amido-PEG4-Boc (2024/9/1)
简介:azido-peg4-amido-peg4-boc is a polyethylene glycol (peg)-based linker for protac synthesis[1].