9月
Boc-N-PEG2-Ms；化合物 T17651Boc-N-PEG2-Ms (2024/9/1)
简介：boc-n-peg2-ms is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-N-Amido-PEG5-Ms；化合物 T17650Boc-N-Amido-PEG5-Ms (2024/9/1)
简介：boc-n-amido-peg5-ms is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Erastin；化合物ErastinErastin (2024/9/1)
简介：erastin is an iron death activator that acts on the mitochondrial vdac in a ros- and iron-dependent manner. erastin has anti-tumor activity and acts selectively on tumor cells with ras-carcinogenic mutations. the product is unstable in solution and is recommended to be dispensed now.
Boc-GABA-OH；N-BOC-GAMMA-氨基丁酸Boc-GABA-OH (2024/9/1)
简介：boc-gaba-oh serves as a protac linker essential for synthesizing unc6852, an eed-targeted protac[1].
Boc-C16-NHS ester；化合物 T17648Boc-C16-NHS ester (2024/9/1)
简介：boc-c16-nhs ester, an alkyl/ether-based protac linker, enables the synthesis of protacs[1].
Boc-C1-PEG3-C4-OH；化合物 T17647Boc-C1-PEG3-C4-OH (2024/9/1)
简介：boc-c1-peg3-c4-oh is an alkyl/ether-based protac linker utilized in the synthesis of protacs, which are characterized by their structure comprising two distinct ligands tethered by a linker. one ligand of protacs binds to an e3 ubiquitin ligase, while the other binds to the target protein. by leveraging the intracellular ubiquitin-proteasome system, protacs facilitate the targeted degradation of specific proteins[1].
Boc-C1-PEG3-C4-OBn；化合物 T17646Boc-C1-PEG3-C4-OBn (2024/9/1)
简介：boc-c1-peg3-c4-obn (protac linker 15) is a peg-based protac linker employed in the synthesis of various protacs, including protac sgk3 degrader-1. protacs are composed of two distinct ligands connected by a linker; one ligand binds to an e3 ubiquitin ligase, while the other specifically interacts with the target protein. by leveraging the intracellular ubiquitin-proteasome system, protacs can selectively degrade target proteins[1].
Boc-aminoxy-PEG4-acid；化合物 T17645Boc-aminoxy-PEG4-acid (2024/9/1)
简介：boc-aminoxy-peg4-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-Aminooxy-PEG5-amine；化合物 T17644Boc-Aminooxy-PEG5-amine (2024/9/1)
简介：boc-aminooxy-peg5-amine is a polyethylene glycol (peg)-based protac linker for the synthesis of protacs.
Boc-Aminooxy-PEG4-CH2-Boc；化合物 T17643Boc-Aminooxy-PEG4-CH2-Boc (2024/9/1)
简介：boc-aminooxy-peg4-ch2-boc is a peg-based linker utilized in the synthesis of protacs.
Boc-Aminooxy-PEG2-bromide；化合物 T17642Boc-Aminooxy-PEG2-bromide (2024/9/1)
简介：boc-aminooxy-peg2-bromide is a two-unit cleavable polyethylene glycol (peg) linker employed specifically in the synthesis of antibody-drug conjugates (adcs)[1].
Boc-aminooxy-amide-PEG4-propargyl；化合物 T17641Boc-aminooxy-amide-PEG4-propargyl (2024/9/1)
简介：boc-aminooxy-amide-peg4-propargyl is a non-cleavable 4-unit polyethylene glycol (peg) linker, commonly employed in the synthesis of antibody-drug conjugates (adcs)[1].
Boc-amino-PEG3-SSPy；化合物 T17640Boc-amino-PEG3-SSPy (2024/9/1)
简介：boc-amino-peg3-sspy is a cleavable 3-unit polyethylene glycol (peg) antibody-drug conjugate (adc) linker employed for synthesizing adcs[1].
Adezmapimod；化合物SB203580PB 203580|||RWJ 64809|||SB203580；PB 203580|||4-(4-氟苯基)-2-(4-甲基亚磺酰基苯基)-5-(4-吡啶 (2024/9/1)
简介：adezmapimod (sb 203580) is a p38 mapk inhibitor (ic50=0.3-0.5 μm) that is selective and atp-competitive. adezmapimod possesses autophagy and mitochondrial autophagy activating activity. adezmapimod displays more than 100-fold higher selectivity than pkb, lck, and gsk-3β.
Boc-amino-PEG3-SS-acid；化合物 T17639Boc-amino-PEG3-SS-acid (2024/9/1)
简介：boc-amino-peg3-ss-acid is a three-unit polyethylene glycol (peg) linker with cleavable properties. it is commonly employed in the synthesis of antibody-drug conjugates (adcs)[1].
Boc-11-aminoundecanoic acid；叔丁氧羰基-11-氨基十一烷酸Boc-11-aminoundecanoic acid (2024/9/1)
简介：boc-11-aminoundecanoic acid is an alkyl/ether-based protac linker that can be used in the synthesis of ms432.
BM-PEG3；1,11-双马来酰亚胺基-3,6,9-三氧代十一烷1,11-Bis-maleimidotetraethyleneglycol；1,11-Bis-maleimidotetraethyle (2024/9/1)
简介：bm-peg3 (1,11-bis-maleimidotetraethyleneglycol) is a peg-based protac linker that can be used in protac synthesis.
Bis-Tos-PEG7；化合物Bis-Tos-PEG7Bis-Tos-PEG7 (2024/9/1)
简介：bis-tos-peg7 is a peg-based protac linker that can be used in protac synthesis.
Bis-Tos-PEG6；化合物 T17635Bis-Tos-PEG6 (2024/9/1)
简介：bis-tos-peg6 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-propargyl-PEG13；化合物 T17634Bis-propargyl-PEG13 (2024/9/1)
简介：bis-propargyl-peg13 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-propargyl-PEG11；化合物 T17633Bis-propargyl-PEG11 (2024/9/1)
简介：bis-propargyl-peg11 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-propargyl-O-PEG17；化合物 T17632Bis-propargyl-O-PEG17 (2024/9/1)
简介：bis-propargyl-o-peg17 is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-PEG9-PFP ester；化合物 T17631Bis-PEG9-PFP ester (2024/9/1)
简介：bis-peg9-pfp ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-(PEG6-acid)-SS；化合物 T17630Bis-(PEG6-acid)-SS (2024/9/1)
简介：bis-(peg6-acid)-ss is a cleavable linker composed of a six-unit peg (polyethylene glycol) moiety. this linker is specifically employed in the synthesis of antibody-drug conjugates (adcs)[1].
SB 525334；化合物SB525334SB525334；SB525334 (2024/9/1)
简介：sb-525334 is a potent and selective inhibitor of the tgf-β1r and alk5 (ic50: 14.3 nm).
Bis-PEG29-acid；化合物 T17629Bis-PEG29-acid (2024/9/1)
简介：bis-peg29-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-PEG25-TFP ester；化合物 T17628Bis-PEG25-TFP ester (2024/9/1)
简介：bis-peg25-tfp ester is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-PEG25-NHS ester；化合物 T17627Bis-PEG25-NHS ester (2024/9/1)
简介：bis-peg25-nhs ester is a cleavable adc linker used in the synthesis of antibody-drug conjugates (adcs)[1].
Bis-PEG25-acid；化合物 T17626Bis-PEG25-acid (2024/9/1)
简介：bis-peg25-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-PEG23-endo-BCN；化合物 T17625Bis-PEG23-endo-BCN (2024/9/1)
简介：bis-peg23-endo-bcn is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
MSN交谈
