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Pantethine-15N2

MCE 国际站：Pantethine-15N2

品牌：MedChemExpress (MCE)

货号：HY-B1028S

Synonyms：D-Pantethine-15N2; LBF disulfide-15N2

存储条件：请按照分析证书中建议的条件储存产品。

运输条件：美国大陆的室温；其他地方可能有所不同。

产品活性：Pantethine-15N2 是 15N2 标记的 Pantethine. Pantethine 是具有口服活性的降血脂剂。Pantethine 具有抗肿瘤、抗炎和抗 SARSCoV 病毒活性。Pantethine 也是神经保护剂。Pantethine 可以用于阿尔兹海默症、帕金森病、重度抑郁症、系统性硬化和泛酸激酶相关神经变性的研究。

生物活性：泛硫乙胺-15N2 是 15N2 标记的泛硫乙胺。泛硫乙胺是一种口服降脂药。泛硫乙胺具有抗肿瘤、抗炎和抗 SARS-COV 病毒活性。泛硫乙胺也是一种神经保护剂。泛硫乙胺可用于研究阿尔茨海默病、帕金森病、重度抑郁症、系统性硬化症和泛酸激酶相关的神经退行性疾病[1][2][3][4][5][6]。

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参考文献：

[1]. Bocos C, et al. Pantethine stimulates lipolysis in adipose tissue ａnd inhibits cholesterol ａnd fatty acid synthesis in liver ａnd intestinal mucosa in the normolipidemic rat. Environ Toxicol Pharmacol. 1998 Aug 4;6(1):59-66.
[2]. Abou-Hamdan M, et al. Potential antiviral effects of pantethine against SARS-CoV-2. Sci Rep. 2023 Feb 8;13(1):2237.
[3]. Penet MF, et al. Effect of Pantethine on Ovarian Tumor Progression ａnd Choline Metabolism. Front Oncol. 2016 Nov 16;6:244.
[4]. Tóth F, et al. Natural Molecules ａnd Neuroprotection: Kynurenic Acid, Pantethine ａnd α-Lipoic Acid. Int J Mol Sci. 2021 Jan 2;22(1):403.
[5]. Kavian N, et al. Pantethine Prevents Murine Systemic Sclerosis Through the Inhibition of Microparticle Shedding. Arthritis Rheumatol. 2015 Jul;67(7):1881-90.
[6]. Brunetti D, et al. Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model. Brain. 2014 Jan;137(Pt 1):57-68.