MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Ro 25-6981 hydrochloride

CAS No. : 919289-58-0

MCE 国际站：Ro 25-6981 hydrochloride

产品活性：Ro 25-6981 Hydrochloride 是一种有效的、选择性和活性依赖性的 NR2B 亚基特异性 NMDA 受体 拮抗剂。Ro 25-6981 Hydrochloride 具有抗惊厥和抗帕金森病活性。Ro 25-6981 Hydrochloride 具有研究帕金森病(PD)的潜力。

研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling

作用靶点：iGluR

In Vitro: Ro 25-6981 Hydrochloride (0.39-12.5 mg/kg; i.p.) induces contraversive rotations in 6-hydroxydopamine (6-OHDA)-lesioned rats without stimulating locomotion in normal rats.
Ro 25-6981 Hydrochloride (1,3 mg/kg; i.p.) exhibits age- ａnd activation-dependent anticonvulsant action at early postnatal development in rats.
Ro 25-6981 Hydrochloride (800 g; intrathecal injection) shows significant analgesic effects on incision pain in rats ａnd effectively attenuated postoperative hyperalgesia induced by remifentanil.

In Vivo: Ro 25-6981 Hydrochloride (0.39-12.5 mg/kg; i.p.) induces contraversive rotations in 6-hydroxydopamine (6-OHDA)-lesioned rats without stimulating locomotion in normal rats.
Ro 25-6981 Hydrochloride (1,3 mg/kg; i.p.) exhibits age- ａnd activation-dependent anticonvulsant action at early postnatal development in rats.
Ro 25-6981 Hydrochloride (800 g; intrathecal injection) shows significant analgesic effects on incision pain in rats ａnd effectively attenuated postoperative hyperalgesia induced by remifentanil.

相关产品：6-Methoxy-2-naphthoic acid | NMDA receptor modulator 4 | CIQ | Budipine | Glycine-¹⁵N,d₂ | AMPA receptor modulator-3 | ZL006 | Orphenadrine hydrochloride | AMPA receptor modulator-2 | (S)-Willardiine | Kynurenic acid-d₅ | Fanapanel | Ifenprodil tartrate | GluN2B receptor modulator-1 | Decanoic acid-d₂ | Coluracetam | Caroverine hydrochloride | L-Phenylalanine-d | Dynorphin A (1-10) (TFA) | L-Glutamic acid-d₅ | JAMI1001A | Sepimostat | NMDA | CFM-2 | Cyclothiazide | JNJ-61432059 | DQP-1105 | L-Glutamic acid-¹³C₅,¹⁵N,d₅ | SYM 2081 | Cycloleucine

热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸 | 抗体 | 点击化学

Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides | Antibodies | Click Chemistry

品牌介绍:
• MCE (MedChemExpress) 拥有200 多种全球独家化合物库，我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物；
• 50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领；
• 产品种类涵盖各种重组蛋白，多肽，常用试剂盒 ，更有 PROTAC、ADC 等特色产品，广泛应用于新药研发、生命科学等科研项目；
• 提供虚拟筛选，离子通道筛选，代谢组学分析检测分析，药物筛选等专业技术服务；
• 设有专业的实验中心和严格的质控、验证体系；
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
• 产品的生物活性多经各国客户实验验证；
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
• 专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
• 与世界各大制药公司及知名科研机构建立了长期的合作。