MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Mepivacaine

CAS No. : 96-88-8

MCE 国际站：Mepivacaine

产品活性：Mepivacaine 是一种酰胺型药剂，可暂时使局部失去知觉。Mepivacaine 与神经元细胞膜上特定的电压门控钠离子通道结合，抑制钠离子内流和膜去极化。

研究领域：Membrane Transporter/Ion Channel

作用靶点：Sodium Channel

In Vitro: Mepivacaine binds to specific voltage-gated sodium ion channels in neuronal cell membranes, which inhibits both sodium influx and membrane depolarization. This leads to a blockage of nerve impulse initiation and conduction and results in a reversible loss of sensation. Compared to other local anesthetics, this agent has a more rapid onset and moderate duration of action.
Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine).
Mepivacaine displays a preferential use-dependent block of Na(v)1.8, S(-)-bupivacaine displays a preference for TTXs Na(+) channels.

相关产品：Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | FDA-Approved Drug Library | Drug Repurposing Compound Library | NMPA-Approved Drug Library | FDA Approved & Pharmacopeial Drug Library | Neuroprotective Compound Library | Drug-Induced Liver Injury (DILI) Compound Library | EIPA | Amiloride hydrochloride | Monensin sodium salt | Carbamazepine | 5-(N,N-Hexamethylene)-amiloride | Riluzole | 20(S)-Ginsenoside Rg3 | Lidocaine | Amitriptyline hydrochloride | Cariporide | Lamotrigine | Ranolazine dihydrochloride | Flecainide acetate | Phenytoin | Zonisamide | Veratridine | Oxcarbazepine | A-803467 | Triamterene | Flunarizine dihydrochloride | Vinpocetine | QX-314 chloride | Dronedarone | Propafenone hydrochloride | Mexiletine hydrochloride | Topiramate

品牌介绍:
• MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；
• 10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；
• 设有专业的实验中心和严格的质控、验证体系；
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；
• 产品的生物活性多经各国客户实验验证；
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；
• 专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；
• 与世界各大制药公司及知名科研机构建立了长期的合作。