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Fenoterol hydrobromide

CAS No. : 1944-12-3

MCE 国际站：Fenoterol hydrobromide

产品活性：Fenoterol hydrobromide (Th-1165a) 是拟交感神经剂，是一种选择性的，具有口服活性 β2-肾上腺素受体 (β2-adrenoceptor) 激动剂。Fenoterol hydrobromide 是一种有效的支气管扩张剂，可用于与哮喘，支气管炎和其他阻塞性气道疾病相关的支气管痉挛的研究。

研究领域：GPCR/G Protein | Neuronal Signaling

作用靶点：Adrenergic Receptor

In Vitro: Fenoterol (1 µM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.
Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.
Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.

In Vivo: Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.

相关产品：Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | Neuronal Signaling Compound Library | FDA-Approved Drug Library | Drug Repurposing Compound Library | Endocrinology Compound Library | Orally Active Compound Library | Neurotransmitter Receptor Compound Library | FDA Approved & Pharmacopeial Drug Library | Exosomes Compound Library | Isoprenaline hydrochloride | ICI 118,551 hydrochloride | Propranolol hydrochloride | Norepinephrine | Phenylephrine hydrochloride | Pimozide | Yohimbine Hydrochloride | Olanzapine | Prazosin hydrochloride | Atenolol | Carvedilol | CL 316243 | Amitriptyline hydrochloride | Dexmedetomidine hydrochloride | L-Epinephrine | Metoprolol Succinate | YS-49 | Pindolol | Dobutamine hydrochloride | Nebivolol hydrochloride | Salmeterol | Labetalol hydrochloride | Perphenazine | (S)-Timolol Maleate | (±)-Bisoprolol hemifumarate | Phentolamine mesylate | Terazosin hydrochloride dihydrate | Ivabradine hydrochloride

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