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Glucagon-like peptide 1 (1-37), human TFA

CAS No. :

MCE 国际站：Glucagon-like peptide 1 (1-37), human TFA

产品活性：Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor.

研究领域：GPCR/G Protein

作用靶点：Glucagon Receptor

In Vitro: Glucagon-like peptide-1 (GLP-1) is produced by the posttranslational processing of proglucagon ａnd acts as a regulator of various homeostatic events. GLP-1(1-37) is more stable than GLP-1(7-37), with 94.7% of the initial amount of peptide left after a 4h exposure to mouse serum. GLP-1(1-37) is confirmed to be a highly potent agonist of the GLP-1 receptor (GLP-1R) by measuring the expression of the luciferase reporter gene expression in transiently transfected human embryonic kidney (HEK293) cells.

In Vivo: GLP-1(1–37) decreases glycemic excursion in a dose-dependent. The administration of GLP-1(1–37) or GLP-1(7–37) markedly decrease blood glucose levels at 15 min ａnd 30 min compared with the control group.

相关产品：Bioactive Compound Library Plus | Exendin-4 | Liraglutide | Glucagon (1-29), bovine, human, porcine | Avexitide | Adomeglivant | GLP-1(7-37) | GLP-1(7-36), amide acetate | BETP | GLP-2(1-33)(human) | GRA Ex-25 | Cotadutide acetate | NNC-0640 | Taspoglutide | GLP-1 moiety from Dulaglutide | Glucagon receptor antagonists-2 | Exendin-3/4 (59-86) | FTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS | GLP-1(28-36)amide | GLP-1(32-36)amide | GLP-1(9-36)amide | Glucagon receptor antagonists-1 | GTFTSDVSKQMEEEAVRLFIEWLKNGGPSSGAPPPS | HAEGTFT | HAEGTFTSD | HAEGTFTSDVS