MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Acriflavine hydrochloride

MCE 国际站：Acriflavine hydrochloride

品牌：MedChemExpress (MCE)

CAS：69235-50-3

纯度：≥97.0%

货号：HY-W088075

中文名称：吖啶黄盐酸盐

Synonyms：吖啶黄盐酸盐; Acriflavinium chloride hydrochloride

存储条件：4°C，密封保存，远离潮湿 *溶剂中：-80°C，6个月；-20°C，1个月（密封保存，远离潮湿）

运输条件：美国大陆的室温；其他地方可能有所不同。

产品活性：Acriflavine hydrochloride (Acriflavinium chloride hydrochloride) 是一种荧光吖啶染料，可用于标记核酸。Acriflavine hydrochloride 是一种防腐剂。Acriflavine hydrochloride 是一种高效的 HIF-1 抑制剂，具有抗肿瘤活性。Acriflavine hydrochloride 具有抗菌和抗病毒活性。Acriflavine hydrochloride 是一种 PLpro 抑制剂，能抑制 SARS-CoV-2。

热销产品：Enasidenib | Liothyronine (sodium) | Phorbol 12,13-dibutyrate | Oseltamivir (phosphate) | C14-4 | Salcaprozate (sodium) | YM-201636 | HTH-01-015 | Azaserine | Cycloastragenol

Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides

参考文献：

[1]. L M Chan, et al. Interaction of acriflavine with DNA ａnd RNA. J Mol Biol. 1969 Mar 28;40(3):491-5.[2]. Thomas Meinelt, et al. Effects of Calcium Content ａnd Humic Substances on the Toxicity of Acriflavine to Juvenile Zebrafish Danio rerio. Journal of Aquatic Animal Health, 14:1, 35-38.[3]. Tao Yin, et al. HIF-1 Dimerization Inhibitor Acriflavine Enhances Antitumor Activity of Sunitinib in Breast Cancer Model. Oncol Res. 2015; 22(3): 139-145.[4]. Román Martí-Díaz, et al. Acriflavine, a Potent Inhibitor of HIF-1α, Disturbs Glucose Metabolism ａnd Suppresses ATF4-Protective Pathways in Melanoma under Non-Hypoxic Conditions. Cancers (Basel). 2021 Jan; 13(1): 102.[5]. Yoshihiro Shimoji, et al. A putative transcription regulator involved in the virulence attenuation of an acriflavine-resistant vaccine strain of Erysipelothrix rhusiopathiae, the causative agent of swine erysipelas. Vet Microbiol. 2019 Dec;239:108488.[6]. Valeria Napolitano, et al. Acriflavine, a clinically aproved drug, inhibits SARS-CoV-2 ａnd other betacoronaviruses. bioRxiv 2021.03.20.436259.