Camidanlumab

MCE 国际站：CAS：921618-45-3

品牌：MedChemExpress (MCE)

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

生物活性：Camidanlumab (HuMax-TAC)是一种CD25单克隆抗体。Camidanlumab靶向细胞表面抗原CD25，该抗原在多种血液学肿瘤中过表达，在正常组织中表达有限。Camidanlumab可用于合成抗体偶联物(antibody agent conjugates, adc)，用于淋巴瘤、白血病等多种疾病的研究
[1]

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研究领域：Cell Cycle/DNA Damage | PI3K/Akt/mTOR | Apoptosis

作用靶点：DNA-PK | Apoptosis

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参考文献：
[1]. Michael J Flynn, et al. ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies. Mol Cancer Ther. 2016 Nov;15(11):2709-2721.

原创作者：MedChemExpress