Mepolizumab

MCE 国际站：Mepolizumab

CAS：196078-29-2

品牌：MedChemExpress (MCE)

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

生物活性：Mepolizumab (SB 240563) 是一种人源化的单克隆抗体，可结合并中和白细胞介素 5 (IL-5)，白细胞介素 5 (IL-5) 是参与嗜酸性粒细胞增殖、活化和存活的主要细胞因子。Mepolizumab 可用于嗜酸性肉芽肿伴多血管炎 (EGPA) 和重度嗜酸性哮喘的研究。

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研究领域：Immunology/Inflammation

作用靶点：Interleukin Related

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参考文献：
[1]. Tim Harrison, et al. Real-world mepolizumab in the prospective severe asthma REALITI-A study: initial analysis. Eur Respir J. 2020 Oct 15;56(4):2000151.
[2]. Ian D Pavord, From DREAM to REALITI-A ａnd beyond: Mepolizumab for the treatment of eosinophil-driven diseases. Allergy. 2022 Mar;77(3):778-797.

原创作者：MedChemExpress