N6-Methyladenosine-d3 | N6-甲基腺苷-d3

MCE 国际站：N6-Methyladenosine-d3

中文名：N6-甲基腺苷-d3

CAS：139896-43-8

品牌：MedChemExpress (MCE)

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

生物活性：N6-Methyladenosine-d3 (6-Methyladenosine-d3; N-Methyladenosine-d3) 是一种氘代标记的 N6-Methyladenosine (HY-N0086)。N6-Methyladenosine 是存在于所有高等真核生物中最普遍的的信使 RNA (mRNA) 内部 (非帽) 修饰。N6-Methyladenosine 可以修饰病毒 RNA，并具有抗病毒活性。

体外：氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱
[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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研究领域：Others

作用靶点：Isotope-Labeled Compounds

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Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides

参考文献：
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-246.
[2]. Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20.
[3]. Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21(8):1511-8.
[4]. Dang W, et al. N6-Methyladenosine ａnd Viral Infection. Front Microbiol. 2019 Mar 5;10:417.

原创作者：MedChemExpress