Netarsudil (dimesylate) | 奈他地尔甲磺酸

MCE 国际站：Netarsudil (dimesylate)

中文名：奈他地尔甲磺酸

CAS：1422144-42-0

品牌：MedChemExpress (MCE)

存储条件：Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

生物活性：Netarsudil mesylate (AR-13324 mesylate) 甲磺酸盐是ROCK激酶和去甲肾上腺素转运体抑制剂。

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研究领域：Cell Cycle/DNA Damage | Stem Cell/Wnt | Cytoskeleton | TGF-beta/Smad

作用靶点：ROCK

热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸

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参考文献：
[1]. Wang RF, et al. Effect of 0.04% AR-13324, a ROCK, ａnd norepinephrine transporter inhibitor, on aqueous humor dynamics in normotensive monkey eyes. J Glaucoma. 2015 Jan;24(1):51-4.
[2]. Levy B, et al. Ocular hypotensive safety ａnd systemic absorption of AR-13324 ophthalmic solution in normal volunteers. Am J Ophthalmol. 2015 May;159(5):980-5.e1.