9月
TCO-PEG4-acid；化合物 T17015TCO-PEG4-acid (2024/9/1)
简介：tco-peg4-acid is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-NHS ester化合物TCO-NHS esterTCO-NHS ester|||TCONHS ester|||TCO NHS ester (2024/9/1)
简介：tco-nhs ester is a alkyl/ether-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
TCO-C3-PEG3-C3-amine；化合物 T17013TCO-C3-PEG3-C3-amine (2024/9/1)
简介：tco-c3-peg3-c3-amine is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
KMRC-20+LUC 人透明细胞肾癌+LUC (2024/9/1)
简介：细胞特性种属: 人源组织来源: 肾疾病: 透明细胞肾癌年龄: 未知性别: 未知细胞类型: 表皮样细胞生长特性: 贴壁生长含量：>1x10^6 细胞数规格：t25瓶或者1ml冻存管包装用途：仅供科研使用。
TCO-amine；化合物 T17012TCO-amine (2024/9/1)
简介：tco-amine is a alkyl chain-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
KMRC-20+LUC 人透明细胞肾癌+LUC (2024/9/1)
简介：细胞特性种属: 人源组织来源: 肾疾病: 透明细胞肾癌年龄: 未知性别: 未知细胞类型: 表皮样细胞生长特性: 贴壁生长含量：>1x10^6 细胞数规格：t25瓶或者1ml冻存管包装用途：仅供科研使用。
TCH-165；化合物TCH-165TCH-165 (2024/9/1)
简介：tch-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20s levels. the increase in the level of free 20s corresponds to enhanced proteolysis of idps.
TC13172；化合物 T17010TC13172 (2024/9/1)
简介：tc13172 is an inhibitor of mixed lineage kinase domain-like protein (ec50: 2 nm for ht-29 cells).
H-ASP-PHE-OH；硫胺杂质BAspartyl-phenylalanine|||Demethylaspartame；Aspartyl-phenylalanine|||硫胺杂质B|||Demeth (2024/9/1)
简介：h-asp-phe-oh (aspartyl-phenylalanine) is used as pharmaceutical intermediates
TC-S 7009；化合物TC-S 7009TC-S 7009 (2024/9/1)
简介：tc-s 7009 is a potent and selective hif-2α inhibitor (kd: 81 nm). the affinity of tc-s 7009 to hif-2α was higher than that of hif-1α (kd >> 5μm). tc-s 7009 disrupts hif-2α heterodimerization, reduces hif-2α target gene expression, and reduces dna binding activity.
TC-S 7005；化合物TC-S 7005TC-S 7005 (2024/9/1)
简介：tc-s 7005 is an effective inhibitor of polo-like kinases (ic50s: 214 nm, 4 nm and 24 nm for plk1, plk2, and plk3).
TC-Mps1-12化合物 T17007TCMps112|||TC-Mps-1-12|||TC Mps1 12 (2024/9/1)
简介：tc-mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (ic50: 6.4 nm) .
KMRC-20+LUC +RFP人透明细胞肾癌+LUC+RFP (2024/9/1)
简介：细胞特性种属: 人源组织来源: 肾疾病: 透明细胞肾癌年龄: 未知性别: 未知细胞类型: 表皮样细胞生长特性: 贴壁生长含量：>1x10^6 细胞数规格：t25瓶或者1ml冻存管包装用途：仅供科研使用。
KMRC-20+LUC +RFP人透明细胞肾癌+LUC+RFP (2024/9/1)
简介：细胞特性种属: 人源组织来源: 肾疾病: 透明细胞肾癌年龄: 未知性别: 未知细胞类型: 表皮样细胞生长特性: 贴壁生长含量：>1x10^6 细胞数规格：t25瓶或者1ml冻存管包装用途：仅供科研使用。
TC-I 2014；化合物TC-I 2014TC-I 2014 (2024/9/1)
简介：tc-i 2014 shows antiallodynic properties in pain models. tc-i 2014 is a potent and orally active benzimidazole-containing transient receptor potential melastatin 8 antagonist (ic50: 0.8 nm, 3.0 nm, and 4.4 nm for canine, human and rat channels respectively).
FPR Agonist 43；FPR激动剂43FPR Agonist 43 (2024/9/1)
简介：fpr agonist 43 is a dual agonist of formyl peptide receptor 1 and formyl peptide receptor 2 (fpr2)/alx.
TC-DAPK 6；化合物TC-DAPK 6TC-DAPK 6 (2024/9/1)
简介：tc-dapk 6 is an atp-competitive inhibitor of death-associated protein kinase (dapk) with ic50s of 69 and 225 nm for dapk1 and dapk3.
TBDMS-PEG4-OH；化合物 T17003TBDMS-PEG4-OH (2024/9/1)
简介：tbdms-peg4-oh is a peg-based linker for protacs which joins two essential ligands, crucial for forming protac molecules. this linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Tazemetostat hydrobromide；氢溴酸泰泽司他E-7438 hydrobromide|||EPZ-6438 hydrobromide；E-7438 hydrobromide|||氢 (2024/9/1)
简介：tazemetostat hydrobromide (e-7438 hydrobromide) is a potent and selective ezh2 inhibitor. tazemetostat hydrobromide inhibits the activity of human polycomb repressive complex 2 (prc2)-containing wild-type ezh2 (ki: 2.5 nm). tazemetostat hydrobromide also inhibits ezh1 (ic50: 392 nm).
Tazanolast；他扎司特Tazalest|||TO 188|||Tazanol；他扎司特|||Tazalest|||TO 188|||Tazanol (2024/9/1)
简介：tazanolast is a selective mast-cell-stabilizing drug.
Tavilermide；化合物 T17000MIM-D3；MIM-D3 (2024/9/1)
简介：tavilermide is a selective and partial agonist of trka or a nerve growth factor mimetic.
KMRC-20+LUC +GFP人透明细胞肾癌+LUC+GFP (2024/9/1)
简介：细胞特性种属: 人源组织来源: 肾疾病: 透明细胞肾癌年龄: 未知性别: 未知细胞类型: 表皮样细胞生长特性: 贴壁生长含量：>1x10^6 细胞数规格：t25瓶或者1ml冻存管包装用途：仅供科研使用。
Tavapadon；化合物TavapadonPF-6649751|||CVL-751；PF-6649751|||CVL-751 (2024/9/1)
简介：tavapadon (cvl-751) is an orally active and highly selective dopamine d1/d5 receptor partial agonist.
KMRC-20+LUC +GFP人透明细胞肾癌+LUC+GFP (2024/9/1)
简介：细胞特性种属: 人源组织来源: 肾疾病: 透明细胞肾癌年龄: 未知性别: 未知细胞类型: 表皮样细胞生长特性: 贴壁生长含量：>1x10^6 细胞数规格：t25瓶或者1ml冻存管包装用途：仅供科研使用。
Tauroursodeoxycholate dihydrate；牛磺熊去氧胆酸二水合物Taurolite dihydrate|||TUDCA dihydrate|||UR 906 dihydrate； (2024/9/1)
简介：tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. tauroursodeoxycholate also inhibits erk. tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-3 and caspase-12.
Tasidotin hydrochloride；化合物 T16997ILX651；ILX651 (2024/9/1)
简介：tasidotin hydrochloride is a peptide analog of the antimitotic depsipeptide dolastatin 15. tasidotin hydrochloride is an inhibitor of microtubule assembly and microtubule dynamics.
TAS6417化合物TAS6417EGFR|||ErbB-1|||TAS-6417 (2024/9/1)
简介：tas6417 is an egfr inhibitor and is an efficacious drug candidate for patients with nsclc (ic50: ranging from 1.1-8.0 nm).
TAS05567；化合物 T16995TAS05567 (2024/9/1)
简介：tas05567 is a potent, highly selective, and atp-competitive syk inhibitor (ic50: 0.37 nm). tas05567 only shows >70% inhibition of syk and 4 other kinases (flt3, jak2, kdr, and ret with ic50s of 10 nm, 4.8 nm, 600 nm, and 29 nm, respectively) in a panel of 192 kinases.
Pimitespib；化合物TAS-116TAS-116；TAS-116 (2024/9/1)
简介：pimitespib (tas-116) is an atp-competitive and highly specific hsp90α/hsp90β inhibitor (kis: 34.7 nm and 21.3 nm, respectively).
Taribavirin；化合物 T16993Taribavirin (2024/9/1)
简介：taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor. taribavirin is designed to concentrate within the liver to target hcv-infected hepatocytes while minimizing distribution within red blood cells (rbcs) and the development of hemolytic anemia.
MSN交谈
