1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70

MCE 国际站：1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70

CAS：56952-01-3

品牌：MedChemExpress (MCE)

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

生物活性：1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 是 1,2-Distearoyl-sn-glycero-3-phosphorylcholine 的氘代物。1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) 是一种脂质，可用于合成脂质体，是脂质纳米颗粒 (LNP) 系

体外：氢、碳和其他元素的稳定重同位素已被掺入药物分子中，主要用作药物开发过程中定量的示踪剂。氘代因其可能影响药物的药代动力学和代谢特征而受到关注
^[1]。

热销产品：Allantoic acid | ABTS (diammonium salt) | Tegafur | Sciadopitysin | (R)-Baclofen | Gefapixant | dTRIM24 | 3-Methyl-2-oxovaleric acid | Streptokinase | Lactoferrin

研究领域：Others

作用靶点：Isotope-Labeled Compounds

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Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides

参考文献：
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Andrew D Miller. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811.
[3]. Jayesh A Kulkarni, et al. On the role of helper lipids in lipid nanoparticle formulations of siRNA. Nanoscale. 2019 Nov 21;11(45):21733-21739.