血管生物反应器循环和生理流体剪切应力模拟工程化组织三维培养装置，血管人工心血管支架搏动测试培养舱,可以用血管、输尿管、胆管、食道、气管循环和生理应力刺激条件下的培养，可以用于人工心血管支架和输尿管支架等搏动灌注条件下测试。血管、人工血管支架循环灌注生物应力培养舱是构建过程中的关键设备，为血管、人工血管支架的体外培养提供稳定的、与生物体内相似的体外环境。目前许多生物反应器在组织工程管状材料重建中得到广泛应用。应力刺激可增加所构建管壁的生物力学性能，利用液体流体动力学原理研制的管状培养舱在构建组织工程管中的作用越来越重要。管道生物反应器多为模块化培养系统。

EBERS vascular culture chamber （patent pending） is designed to grow vascular tissue on cylindrical-shaped scaffolds accounting for internal ａnd external culture media flows. Furthermore, special effort has been spent in developing a simple system able to host a wide range of scaffold sizes, both in diameter ａnd in length.

The most relevant parts of the vascular chamber ａnd its working configuration are shown below.ch

Forming parts

The chamber is composed two parts forming internal ａnd external flow circuits, respectively. The gap in the internal circuit is filLED with vessel scaffold, allowing pumping fluid media inside the scaffold lumen.

The external circuit aims to circulate culture media over the external surface of the scaffold so nutrients are delivered to the outer surface.

Adaptable working length

In order to fit different scaffolds sizes, the working length in between the tube edges of the inner circuit may be adjusted, always guaranteeing no fluid leakage.

Since the scaffold diameter may be also vary depending of the kind of vessel, we CAN modify the dimensions of the tubing in order to customize the chamber for your particular application.

Working configuration

Once the chamber is locked, the system is ready to be connected to the culture circuit. The number of tube docks may be variable depending on the particular needs of the experiment.

Although the standard configuration it has four input/output ports, the chamber may be modified in order to adapt the number of ports to the demands of your experimental set-up.

After the scaffold is fixed closing the internal circuit ａnd the chamber is locked, silicone tubing is connected to the ports to create two independent circuits.

Flow conditions may be independently applied to each of the circuits by using, e.g., the EBERS Master Unit.

Visit the technical specifications page for further information on the EBERS vascular chambers.