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FITC标记的磷酸化细胞分裂周期蛋白16抗体
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价格：￥电议
更新日期：2026/8/7 18:14:45
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相关标签：FITC标记的磷酸化细胞分裂周期蛋白16抗体
详细内容
| 英文名称 | Anti-phospho-CDC16(Ser560)/FITC |
| 中文名称 | FITC标记的磷酸化细胞分裂周期蛋白16抗体 |
| 别 名 | Apc6 (phospho S560); p-Apc6 (phospho S560); ANAPC6; Anaphase promoting complex subunit 6; Anaphase-promoting complex subunit 6; Apc 6; APC6; CDC 16; Apc6 (phospho S560): p-Apc6(S560); CDC16 (cell division cycle 16 S. cerevisiae homolog); CDC16; CDC16 homolog; CDC16 protein; CDC16_HUMAN; CDC16Hs; Cell division cycle 16 homolog; Cell division cycle protein 16 homolog; CUT9; Cyclosome subunit 6. |
| 说 明 书 | 100ul |
| 产品类型 | 磷酸化抗体 |
| 研究领域 | 细胞生物 细胞周期蛋白 细胞分化 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 72kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthesised phosphopeptide derived from human APC6 around the phosphorylation site of Ser560 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Cell cycle events are regulated by the sequential activation ａnd deactivation of cyclin dependent kinases (Cdks) ａnd by the proteolysis of cyclins. The cell division cycle (Cdc) genes are required at various points in the cell cycle. Cdc25A, Cdc25B ａnd Cdc25C protein tyrosine phosphatases function as mitotic activators by dephosphorylating Cdc2 p34 on regulatory tyrosine residues. Cdc6 is the human homolog of Saccharomyces cerevisiae Cdc6, which is involved in the initiation of DNA replication. Cdc37 appears to facilitate Cdk4/cyclin D1 complex formation ａnd has been shown to form a stable complex with Hsp90. Cdc34, Cdc27 ａnd Cdc16 function as ubiquitin-conjugating enzymes. Cdc34 is thought to be the structural ａnd functional homolog of Saccharomyces cerevisiae Cdc34, which is essential for the G1 to S phase transition. Cdc16 ａnd Cdc27 are components of the APC (anaphase-promoting complex) which ubiquitinates cyclin B, resulting in cyclin B/Cdk complex degradation. Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis ａnd the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination ａnd subsequent degradation of target proteins: it mainly mediates the formation of ＇Lys-11＇-linked polyubiquitin chains and, to a lower extent, the formation of ＇Lys-48＇- ａnd ＇Lys-63＇-linked polyubiquitin chains. |
FITC标记的磷酸化细胞分裂周期蛋白16抗体
