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FITC标记的睾丸酸性磷酸酶抗体

FITC标记的睾丸酸性磷酸酶抗体

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价格:¥电议

更新日期:2026/8/7 18:14:45

生 产 地:中国大陆

产品型号:

简单介绍:FITC标记的睾丸酸性磷酸酶抗体产品介绍:This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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相关标签:FITC标记的睾丸酸性磷酸酶抗体

详细内容

英文名称 Anti-ACPT/FITC
中文名称 FITC标记的睾丸酸性磷酸酶抗体
别 名 Acid phosphatase testicular; Testicular acid phosphatase; PPAT_HUMAN.
说 明 书 100ul
研究领域 肿瘤 细胞生物 信号转导 生长因子和激素 转录调节因子 肿瘤细胞生物标志物
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse,
产品应用 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACPT
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is upregulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. ACPT dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. ACPT is predominantly expressed in testis but exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Tissue Specificity:
High levels in pancreatic, gastric, colorectal and ampullary cancer. Very weak expression in normal gastrointestinal and urogenital tract.

Similarity:
Belongs to the peptidase S1 family.
Contains 1 LDL-receptor class A domain.
Contains 1 peptidase S1 domain.
Contains 1 SRCR domain.
FITC标记的睾丸酸性磷酸酶抗体

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