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FITC标记的信号转导衔接结合蛋白抗体
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价格：￥电议
更新日期：2026/8/7 18:14:45
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相关标签：FITC标记的信号转导衔接结合蛋白抗体
详细内容
| 英文名称 | Anti-AMSH/FITC |
| 中文名称 | FITC标记的信号转导衔接结合蛋白抗体 |
| 别 名 | Associated molecule with the SH3 domain of STAM; Endosome associated ubiquitin isopeptidase; Endosome-associated ubiquitin isopeptidase; STABP_HUMAN; STAM binding protein; STAM-binding protein; STAMBP. |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞周期蛋白 结合蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Horse, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AMSH |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Zinc metalloprotease that specifically cleaves ＇Lys-63＇-linked polyubiquitin chains. Does not cleave ＇Lys-48＇-linked polyubiquitin chains (By similarity). Functions at the endosome ａnd is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth ａnd MYC induction mediated by IL-2 ａnd GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 ａnd SMAD7. Function: Zinc metalloprotease that specifically cleaves ＇Lys-63＇-linked polyubiquitin chains. Does not cleave ＇Lys-48＇-linked polyubiquitin chains (By similarity). Functions at the endosome ａnd is able to oppose the ubiquitin-dependent sorting of receptors to lysosomes. Plays a role in signal transduction for cell growth ａnd MYC induction mediated by IL-2 ａnd GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 ａnd SMAD7. Subcellular Location: Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Early endosome. Tissue Specificity: Ubiquitously expressed. Post-translational modifications: Phosphorylated after BMP type I receptor activation. Ubiquitinated by SMURF2 in the presence of RNF11. Similarity: Belongs to the peptidase M67C family. Contains 1 MPN (JAB/Mov34) domain. |
FITC标记的信号转导衔接结合蛋白抗体
