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FITC标记的凋亡诱导蛋白D抗体
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价格：￥电议
更新日期：2026/8/7 18:14:45
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相关标签：FITC标记的凋亡诱导蛋白D抗体
详细内容
| 英文名称 | Anti-APPD/FITC |
| 中文名称 | FITC标记的凋亡诱导蛋白D抗体 |
| 别 名 | PKHF1_HUMAN; Apoptosis inducing protein D; LAPF; Lysosome associated apoptosis inducing protein containing PH ａnd FYVE domains; MGC4090; PH ａnd FYVE domain containing protein 1; PH domain containing family F member 1; Phafin 1; Pleckstrin homology domain containing family F (with FYVE domain) member 1; Pleckstrin homology domain containing family F member 1; Pleckstrin homology domain containing family F with FYVE domain member 1; PLEKHF1; ZFYVE15; Zinc finger FYVE domain containing protein 15. |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 细胞凋亡 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human APPD/LAPF (75-124aa) |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: APPD is a lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) ａnd FYVE domains (LAPF). It is a representative of a novel family of PH ａnd FYVE domain-containing proteins ａnd induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway. Cellular localization: Nucleus. Cytoplasm, perinuclear region. Lysosome. Note=Translocates to lysosome during apoptosis. Function: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) ａnd resulting in the release of CTSD ａnd CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8. Subcellular Location: Nucleus. Cytoplasm, perinuclear region. Lysosome. Note=Translocates to lysosome during apoptosis. Tissue Specificity: Highly expressed in heart ａnd skeletal muscle. Weakly expressed in brain, thymus, spleen, kidney, liver, small intestine, placenta ａnd lung. Similarity: Contains 1 FYVE-type zinc finger. Contains 1 PH domain. Database links: UniProtKB/Swiss-Prot: Q96S99.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
FITC标记的凋亡诱导蛋白D抗体
