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FITC标记的载脂蛋白B受体抗体
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价格：￥电议
更新日期：2026/8/7 18:14:45
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相关标签：FITC标记的载脂蛋白B受体抗体
详细内容
| 英文名称 | Anti-APOB48R/FITC |
| 中文名称 | FITC标记的载脂蛋白B受体抗体 |
| 别 名 | apo b-100; APOB; apoB-48R; apoB-100R; apoB100R; Apolipoprotein B-100 receptor; Apolipoprotein B100 receptor; Apolipoprotein B48 receptor. |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 免疫学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 115kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human APOB48R |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: APOB48R is a macrophage receptor that binds to the apolipoprotein B48 of dietary triglyceride (TG) rich lipoproteins. It may provide essential lipids, lipid soluble vitamins ａnd other nutrients to reticuloendothelial cells. Function: Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds ａnd internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL ａnd remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG-VLDL, ａnd trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages. Subunit: Homodimer. Subcellular Location: Cell membrane; Peripheral membrane protein. Note=Binds monocyte-macrophage membrane. Thought to be anchored in the membrane through an interaction with an integral membrane protein. Tissue Specificity: Expressed in peripheral blood leukocytes > bone marrow = spleen > lymph node, ａnd only faintly visible in appendix ａnd thymus. Expressed in the brain, heart, kidney, liver, lung, pancreas, ａnd placenta. Expressed primarily by reticuloendothelial cells: monocytes, macrophages, ａnd endothelial cells. Expressed in atherosclerotic lesion foam cells. Post-translational modifications: There are 2 forms in macrophages, the membrane-binding proteins 200 kDa (MBP 200) ａnd 235 kDa (MBP 235), that can be reduced into a single active ligand-binding species with intermediate mobility (MBP 200R). Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
FITC标记的载脂蛋白B受体抗体
