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TGFβ RIII Polyclonal Antibody转化生长因子β受体3 多克隆抗体 (2017/1/25)
简介：tgfbr3（transforming growth factor beta receptor 3） encodes the transforming growth factor (tgf)-beta type iii receptor. the encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other tgf-beta receptor superfamily members. ectodomain shedding produces soluble tgfbr3, which may inhibit tgfb signaling. decreased expression of this receptor has been observed in various cancers. alternatively spliced transcript variants encoding different isoforms have been identifie
TGFβ RIII Polyclonal Antibody转化生长因子β受体3 多克隆抗体 (2017/1/25)
简介：tgfbr3（transforming growth factor beta receptor 3） encodes the transforming growth factor (tgf)-beta type iii receptor. the encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other tgf-beta receptor superfamily members. ectodomain shedding produces soluble tgfbr3, which may inhibit tgfb signaling. decreased expression of this receptor has been observed in various cancers. alternatively spliced transcript variants encoding different isoforms have been identifie
TGFβ RIII Polyclonal Antibody转化生长因子β受体3 多克隆抗体 (2017/1/25)
简介：tgfbr3（transforming growth factor beta receptor 3） encodes the transforming growth factor (tgf)-beta type iii receptor. the encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other tgf-beta receptor superfamily members. ectodomain shedding produces soluble tgfbr3, which may inhibit tgfb signaling. decreased expression of this receptor has been observed in various cancers. alternatively spliced transcript variants encoding different isoforms have been identifie
TGFβ RIII (phospho Thr842) Polyclonal Antibody转化生长因子β受体3 (phospho Thr842) 多克隆抗体 (2017/1/25)
简介：tgfbr3（transforming growth factor beta receptor 3） encodes the transforming growth factor (tgf)-beta type iii receptor. the encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other tgf-beta receptor superfamily members. ectodomain shedding produces soluble tgfbr3, which may inhibit tgfb signaling. decreased expression of this receptor has been observed in various cancers. alternatively spliced transcript variants encoding different isoforms have been identifie
TGFβ RII Polyclonal Antibody转化生长因子β受体2 多克隆抗体 (2017/1/25)
简介：tgfbr2 encodes a member of the ser/thr protein kinase family and the tgfb receptor subfamily. the tgf-beta receptor type-2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds tgf-beta. this receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. mutations in this gene have been associated with marfan syndrome, loe
TGFβ RII Polyclonal Antibody转化生长因子β受体2 多克隆抗体 (2017/1/25)
简介：tgfbr2 encodes a member of the ser/thr protein kinase family and the tgfb receptor subfamily. the tgf-beta receptor type-2 is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds tgf-beta. this receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. mutations in this gene have been associated with marfan syndrome, loe
TGFβ RII (phospho Ser225) Polyclonal Antibody转化生长因子β受体2 (phospho Ser225) 多克隆抗体 (2017/1/25)
简介：tgfbr2（transforming growth factor beta receptor 2） encodes a member of the ser/thr protein kinase family and the tgfb receptor subfamily. the encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds tgf-beta. this receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. mutations in tgfbr2 have been asso
TGFβ RI Polyclonal Antibody转化生长因子β受体1 多克隆抗体 (2017/1/25)
简介：tgf-beta receptor type-1 encoded by tgfbr1 forms a heteromeric complex with type ii tgf-beta receptors when bound to tgf-beta, transducing the tgf-beta signal from the cell surface to the cytoplasm. the tgf-beta receptor type-1 is a serine/threonine protein kinase. mutations in this gene have been associated with loeys-dietz aortic aneurysm syndrome (ldas). multiple transcript variants encoding different isoforms have been found for this gene.蛋白别名为：tgfbr1; alk5; skr4; tgf-beta receptor type
TGFβ RI (phospho Ser165) Polyclonal Antibody转化生长因子β受体1 (phospho Ser165) 多克隆抗体 (2017/1/25)
简介：the protein encoded by tgfbr1（transforming growth factor beta receptor 1） forms a heteromeric complex with type ii tgf-beta receptors when bound to tgf-beta, transducing the tgf-beta signal from the cell surface to the cytoplasm. the encoded protein is a serine/threonine protein kinase. mutations in tgfbr1 have been associated with loeys-dietz aortic aneurysm syndrome (ldas). multiple transcript variants encoding different isoforms have been found for tgfbr1.蛋白别名为：tgfbr1; alk5; skr4; tgf-be
TGFα Polyclonal Antibody转化生长因子α 多克隆抗体 (2017/1/25)
简介：tgfa（transforming growth factor alpha） encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. this protein may act as either a transmembrane-bound ligand or a soluble ligand. tgfa has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. alternatively spliced transcript variants encoding different isoforms have been found fo
TGFα Polyclonal Antibody转化生长因子α 多克隆抗体 (2017/1/25)
简介：tgfa encodes a growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and development. protransforming growth factor alpha may act as either a transmembrane-bound ligand or a soluble ligand. this gene has been associated with many types of cancers, and it may also be involved in some cases of cleft lip/palate. alternatively spliced transcript variants encoding different isoforms have been found for this
TGase2 Polyclonal Antibody转谷氨酰酶2 多克隆抗体 (2017/1/25)
简介：transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. while the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. protein-glutamine gamma-glutamyltransferase 2 encoded by tgm2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. finally, the protein-glutamine gamma-glutamyltransfe
TG1019 Polyclonal Antibody氧桥二十烷受体1 多克隆抗体 (2017/1/25)
简介：oxer1 (oxoeicosanoid (oxe) receptor 1) is a protein coding gene. among its related pathways are signaling by gpcr and peptide ligand-binding receptors. go annotations related to this gene include g-protein coupled receptor activity and 5-hydroxy-6e,8z,11z,14z-icosatetraenoic acid binding. an important paralog of this gene is hcar3.receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6e,8z,11z,14z-eicosatetraenoic acid (5-oxo-ete), 5(s)-hydroperoxy-6e,8z,11z,14z-eicosatetraenoic
TFPI-2 Polyclonal Antibody组织因子途径抑制因子2 多克隆抗体 (2017/1/25)
简介：tfpi2 encodes a member of the kunitz-type serine proteinase inhibitor family. tissue factor pathway inhibitor 2 can inhibit a variety of serine proteases including factor viia/tissue factor, factor xa, plasmin, trypsin, chymotryspin and plasma kallikrein. this gene has been identified as a tumor suppressor gene in several types of cancer. alternative splicing results in multiple transcript variants. 蛋白别名为：tfpi2; tissue factor pathway inhibitor 2; tfpi-2; placental protein 5; pp5;基因id为：7980；
TFPI Polyclonal Antibody组织因子途径抑制因子 多克隆抗体 (2017/1/25)
简介：tfpi encodes a kunitz-type serine protease inhibitor that regulates the tissue factor (tf)-dependent pathway of blood coagulation. the coagulation process initiates with the formation of a factor viia-tf complex, which proteolytically activates additional proteases (factors ix and x) and ultimately leads to the formation of a fibrin clot. the product of this gene inhibits the activated factor x and viia-tf proteases in an autoregulatory loop. inhibition of the encoded protein restores hemostasis
TFIIIC90 Polyclonal Antibody通用转录因子3C多肽4 多克隆抗体 (2017/1/25)
简介：gtf3c4, also named as tfiiic90, is essential for rna polymerase iii to make a number of small nuclear and cytoplasmic rnas, including 5s rna, trna, and adenovirus-associated (va) rna of both cellular and viral origin. it has histone acetyltransferase activity (hat) with unique specificity for free and nucleosomal h3.蛋白别名为：gtf3c4; general transcription factor 3c polypeptide 4; tf3c-delta; transcription factor iiic 90 kda subunit; tfiiic 90 kda subunit; tfiiic90; transcription factor iiic sub
TFIIIC110 Polyclonal Antibody通用转录因子3C多肽2 多克隆抗体 (2017/1/25)
简介：required for rna polymerase iii-mediated transcription. component of tfiiic that initiates transcription complex assembly on trna and is required for transcription of 5s rrna and other stable nuclear and cytoplasmic rnas. may play a direct role in stabilizing interactions of tfiiic2 with tfiiic1.蛋白别名为：gtf3c2; kiaa0011; general transcription factor 3c polypeptide 2; tf3c-beta; transcription factor iiic 110 kda subunit; tfiiic 110 kda subunit; tfiiic110; transcription factor iiic subunit beta
TFIIIC102 Polyclonal Antibody通用转录因子3C多肽3 多克隆抗体 (2017/1/25)
简介：general transcription factor 3c polypeptide 3 encoded by gtf3c3 is part of the tfiiic2 complex, which binds to the promoters of small nuclear and cytoplasmic rna genes in order to recruit rna polymerase iii. the tfiiic2 complex is composed of six subunits. two transcript variants encoding different isoforms have been found for this gene. 蛋白别名为：gtf3c3; general transcription factor 3c polypeptide 3; transcription factor iiic 102 kda subunit; tfiiic 102 kda subunit; tfiiic102; transcription fa
TFIIIB90-1 Polyclonal AntibodyRNA聚合酶III转录启动因子IIIB亚基 多克隆抗体 (2017/1/25)
简介：brf1 encodes one of the three subunits of the rna polymerase iii transcription factor complex. this complex plays a central role in transcription initiation by rna polymerase iii on genes encoding trna, 5s rrna, and other small structural rnas. the gene product belongs to the tf2b family. several alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by rna polymerase iii, have been identified. 蛋白别名为：brf1; brf; gtf3b; taf3b2; taf3c; tran
TFIIIA Polyclonal Antibody通用转录因子IIIA 多克隆抗体 (2017/1/25)
简介：the product of gtf3a is a zinc finger protein with nine cis[2]-his[2] zinc finger domains. it functions as an rna polymerase iii transcription factor to induce transcription of the 5s rrna genes. the protein binds to a 50 bp internal promoter in the 5s genes called the internal control region (icr), and nucleates formation of a stable preinitiation complex. this complex recruits the tfiiic and tfiiib transcription factors and rna polymerase iii to form the complete transcription complex. the pro
TFII-I (phospho Tyr248) Polyclonal Antibody通用转录因子2-I (phospho Tyr248) 多克隆抗体 (2017/1/25)
简介：gtf2i encodes a phosphoprotein containing six characteristic repeat motifs. the general transcription factor iii binds to the initiator element (inr) and e-box element in promoters and functions as a regulator of transcription. this locus, along with several other neighboring genes, is deleted in williams-beuren syndrome. there are many closely related genes and pseudogenes for this gene on chromosome 7. this gene also has pseudogenes on chromosomes 9, 13, and 21. alternatively spliced transcrip
TFIIH p62 Polyclonal Antibody通用转录因子2H亚基1 多克隆抗体 (2017/1/25)
简介：component of the core-tfiih basal transcription factor involved in nucleotide excision repair (ner) of dna and, when complexed to cak, in rna transcription by rna polymerase ii.蛋白别名为：gtf2h1; btf2; general transcription factor iih subunit 1; basic transcription factor 2 62 kda subunit; btf2 p62; general transcription factor iih polypeptide 1; tfiih basal transcription factor complex p62 subunit;基因id为：2965；蛋白质id:p32780
TFIIH p44 Polyclonal Antibody通用转录因子2H亚基2 多克隆抗体 (2017/1/25)
简介：gtf2h2 is part of a 500 kb inverted duplication on chromosome 5q13. this duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. the repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. gtf2h2 is within the telomeric copy of the duplication. deletion of this gene sometimes accompanies deletion of the neighboring smn1 gene in spinal muscular atrophy (sma
TFIIE-β Polyclonal Antibody通用转录因子2E亚基β 多克隆抗体 (2017/1/25)
简介：gtf2e2 (general transcription factor iie subunit 2) is a protein coding gene. among its related pathways are gene expression and hiv life cycle. go annotations related to this gene include poly(a) rna binding.recruits tfiih to the initiation complex and stimulates the rna polymerase ii c-terminal domain kinase and dna-dependent atpase activities of tfiih. both tfiih and tfiie are required for promoter clearance by rna polymerase.蛋白别名为：gtf2e2; tf2e2; transcription initiation factor iie subun
TFIID Polyclonal AntibodyTATA框结合蛋白 多克隆抗体 (2017/1/25)
简介：initiation of transcription by rna polymerase ii requires the activities of more than 70 polypeptides. tata-box-binding protein that coordinates these activities is transcription factor iid (tfiid), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. tfiid is composed of the tata-binding protein (tbp) and a group of evolutionarily conserved proteins k
TFIIA-α Polyclonal Antibody通用转录因子IIA亚基1 多克隆抗体 (2017/1/25)
简介：accurate transcription initiation on tata-containing class ii genes involves the ordered assembly of rna polymerase ii (polr2a; mim 180660) and several general initiation factors (summarized by dejong and roeder, 1993 [pubmed 8224848]). one of these factors is tfiia, which when purified from hela extracts consists of 35-, 19-, and 12-kd subunits.蛋白别名为：gtf2a1; tf2a1; transcription initiation factor iia subunit 1; general transcription factor iia subunit 1; tfiial; transcription initiation fa
TFEB Polyclonal Antibody转录因子EB 多克隆抗体 (2017/1/25)
简介：transcription factor eb (tfeb) is a member of the myc-related, bhlh leucine-zipper family of transcription factors that drives the expression of a network of genes known as the coordinated lysosomal expression and regulation (clear) network. tfeb specifically recognizes and binds regulatory sequences within the clear box (gtcacgtgac) of lysosomal and autophagy genes, resulting in the up-regulated expression of genes involved in lysosome biogenesis and function, and regulation of autophagy . tfeb
TFE3 Polyclonal Antibody转录因子E3 多克隆抗体 (2017/1/25)
简介：tfe3 （transcription factor binding to ighm enhancer 3）encodes a basic helix-loop-helix domain-containing transcription factor that binds mue3-type e-box sequences in the promoter of genes. the encoded protein promotes the expression of genes downstream of transforming growth factor beta (tgf-beta) signaling. tfe3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. translocation partners include prcc (papillary
TFDP1 Polyclonal Antibody转录因子DP1 多克隆抗体 (2017/1/25)
简介：tfdp1 encodes a member of a family of transcription factors that heterodimerize with e2f proteins to enhance their dna-binding activity and promote transcription from e2f target genes. the encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from g1 to s phase. alternative splicing results in multiple transcript variants. pseudogenes of this gene are found on chromosomes 1, 15, and x.蛋白别名为：tfdp1; dp1;
TF Polyclonal Antibody凝血因子3 多克隆抗体 (2017/1/25)
简介：tf（transferrin） encodes a glycoprotein with an approximate molecular weight of 76.5 kda. it is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous c and n-terminal domains each of which binds one ion of ferric iron. the function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. this protein may also have a physiologic role as granul
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