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PRP6 Polyclonal Antibody前mRNA加工因子6 多克隆抗体 (2017/1/22)
简介：the pre-mrna processing factor 6 encoded by prpf6 appears to be involved in pre-mrna splicing, possibly acting as a bridging factor between u5 and u4/u6 snrnps in formation of the spliceosome. the encoded protein also can bind androgen receptor, providing a link between transcriptional activation and splicing.蛋白别名为：prpf6; c20orf14; pre-mrna-processing factor 6; androgen receptor n-terminal domain-transactivating protein 1; ant-1; prp6 homolog; u5 snrnp-associated 102 kda protein; u5-102 kda
PRP19 Polyclonal Antibody前mRNA加工因子19 多克隆抗体 (2017/1/22)
简介：pso4 is the human homolog of yeast pso4, a gene essential for cell survival and dna repair蛋白别名为：prpf19; nmp200; prp19; snev; pre-mrna-processing factor 19; nuclear matrix protein 200; prp19/pso4 homolog; hpso4; senescence evasion factor;基因id为：27339；蛋白质id:q9ums4
Protocadherin-11 Polyclonal AntibodyY-连锁原粘蛋白11 多克隆抗体 (2017/1/22)
简介：pcdh11y（protocadherin 11 y-linked） belongs to the protocadherin family, a subfamily of the cadherin superfamily. the encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical cadherins. pcdh11y is located on the y chromosome in a block of x/y homology and is very closely related to its paralog on the x chromosome. the protein is thought to play a role in cell-cell recognition duri
Prothrombin Polyclonal Antibody凝血因子II 多克隆抗体 (2017/1/22)
简介：coagulation factor ii is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. f2 also plays a role in maintaining vascular integrity during development and postnatal life. peptides derived from the c-terminus of this protein have antimicrobial activity against e. coli and p. aeruginosa. mutations in f2 lead to various forms of thrombosis and dysprothrombinemia. alternative splicing results in multiple transc
Prothrombin Polyclonal Antibody凝血因子II 多克隆抗体 (2017/1/22)
简介：coagulation factor ii is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. f2 also plays a role in maintaining vascular integrity during development and postnatal life. peptides derived from the c-terminus of this protein have antimicrobial activity against e. coli and p. aeruginosa. mutations in f2 lead to various forms of thrombosis and dysprothrombinemia. alternative splicing results in multiple transc
Protein C Polyclonal Antibody蛋白C(凝血因子Va 和VIIIa 抑制因子) 多克隆抗体 (2017/1/22)
简介：proc encodes a vitamin k-dependent plasma glycoprotein. the vitamin k-dependent protein c is cleaved to its activated form by the thrombin-thrombomodulin complex. this activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors v and viii. mutations in this gene have been associated with thrombophilia due to protein c deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.蛋白别名为：proc; vitamin k-dependent protein
Prolactin Polyclonal Antibody催乳素 多克隆抗体 (2017/1/22)
简介：prl encodes the anterior pituitary hormone prolactin. this secreted hormone is a growth regulator for many tissues, including cells of the immune system. it may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. alternative splicing results in multiple transcript variants that encode the same protein.蛋白别名为：prl; prolactin; prl;基因id为：5617；蛋白质id:p01236
Probetacellulin Polyclonal Antibodyβ细胞素原 多克隆抗体 (2017/1/22)
简介：btc encodes a member of the epidermal growth factor (egf) family of proteins. alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. a secreted form and a membrane-anchored form of this protein bind to multiple different egf receptors. this protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. mutations in this ge
Probetacellulin Polyclonal Antibodyβ细胞素原 多克隆抗体 (2017/1/22)
简介：btc encodes a member of the epidermal growth factor (egf) family of proteins. alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. a secreted form and a membrane-anchored form of betacellulin bind to multiple different egf receptors. betacellulin romotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. mutations in btc may
PRKY Polyclonal AntibodyY-连锁蛋白激酶 多克隆抗体 (2017/1/22)
简介：prkx（protein kinase, x-linked） encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic amp dependent protein kinases. the encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. this protein may also be involved in macrophage and granulocyte maturation. abnormal recombination between prkx and a related pseudogene on chromosome y is a frequent cause of sex reversal disorder in xx males and xy females. pseudogenes
PRKX Polyclonal AntibodyX-连锁蛋白激酶 多克隆抗体 (2017/1/22)
简介：prkx（protein kinase, x-linked） encodes a serine threonine protein kinase that has similarity to the catalytic subunit of cyclic amp dependent protein kinases. the encoded protein is developmentally regulated and may be involved in renal epithelial morphogenesis. this protein may also be involved in macrophage and granulocyte maturation. abnormal recombination between prkx and a related pseudogene on chromosome y is a frequent cause of sex reversal disorder in xx males and xy females. pseudogenes
PRIM1 Polyclonal Antibody引发酶肽1 多克隆抗体 (2017/1/22)
简介：the replication of dna in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which dna polymerase alpha and primase are two key enzymatic components. primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small rna primers for the okazaki fragments made during discontinuous dna replication. pimase (dna) subunit 1 ncoded by prim1 is the small, 49 kda primase subunit蛋白别名为：prim1; dna primase small subunit; dna primase 49 kda subunit;
PRIC285 Polyclonal Antibody过氧化物酶体增殖因子活化受体A结合复合体285 多克隆抗体 (2017/1/22)
简介：the protein encoded by helz2 （helicase with zinc finger 2）is a nuclear transcriptional co-activator for peroxisome proliferator activated receptor alpha. the encoded protein contains a zinc finger and is a helicase that appears to be part of the peroxisome proliferator activated receptor alpha interacting complex. helz2 is a member of the dna2/nam7 helicase gene family. alternatively spliced transcript variants encoding different isoforms have been found for helz2.蛋白别名为：pric285; kiaa1769; p
Presenilin 2 (phospho Ser330) Polyclonal Antibody早衰蛋白2 (phospho Ser330) 多克隆抗体 (2017/1/22)
简介：alzheimer´s disease (ad) patients with an inherited form of the disease carry mutations in the presenilin proteins (psen1 or psen2) or the amyloid precursor protein (app). these disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in ad brains). presenilins are postulated to regulate app processing through their effects on gamma-secretase, an enzyme that cleaves app. also, it is thought that the presenilins are
Presenilin 1 Polyclonal Antibody早衰蛋白1 多克隆抗体 (2017/1/22)
简介：alzheimer´s disease (ad) patients with an inherited form of the disease carry mutations in the presenilin proteins (psen1; psen2) or in the amyloid precursor protein (app). these disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in ad brains). presenilins are postulated to regulate app processing through their effects on gamma-secretase, an enzyme that cleaves app. also, it is thought that the presenilins ar
Presenilin 1 (phospho Ser357) Polyclonal Antibody早衰蛋白1 (phospho Ser357) 多克隆抗体 (2017/1/22)
简介：alzheimer´s disease (ad) patients with an inherited form of the disease carry mutations in the presenilin proteins (psen1; psen2) or in the amyloid precursor protein (app). these disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in ad brains). presenilins are postulated to regulate app processing through their effects on gamma-secretase, an enzyme that cleaves app. also, it is thought that the presenilins ar
PREP-2 Polyclonal Antibody同源框蛋白PREP2 多克隆抗体 (2017/1/22)
简介：homeodomain proteins are sequence-specific transcription factors that share a highly conserved dna-binding domain and play fundamental roles in cell proliferation, differentiation, and death. pknox2 belongs to the tale (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain蛋白别名为：pknox2; prep2; homeobox protein pknox2; homeobox protein prep-2; pbx/knotted homeobox 2;基因id为：63876；蛋白质id:q96kn3
PREP Polyclonal Antibody脯氨酰内肽酶 多克隆抗体 (2017/1/22)
简介：prolyl endopeptidase encoded by prep is a cytosolic prolyl endopeptidase that cleaves peptide bonds on the c-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. prolyl endopeptidases have been reported to be involved in the maturation and degradation of peptide hormones and neuropeptides.蛋白别名为：prep; pep; prolyl endopeptidase; pe; post-proline cleaving enzyme;基因id为：5550；蛋白质id:q8n6d4
Prefoldin 1 Polyclonal Antibody前折叠蛋白亚基1 多克隆抗体 (2017/1/22)
简介：pfdn1（prefoldin subunit 1） encodes a member of the prefoldin beta subunit family. the encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. the complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.蛋白别名为：pfdn1; pfd1; prefoldin subunit 1;基因id为：5201；蛋白质id:o60925
PRDM3 Polyclonal Antibody骨髓增生异常综合征1蛋白 多克隆抗体 (2017/1/22)
简介：the protein encoded by mecom is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. the encoded protein can interact with ctbp1, smad3, crebbp, kat2b, mapk8, and mapk9. this gene can undergo translocation with the aml1 gene, resulting in overexpression of this gene and the onset of leukemia. several transcript variants encoding a few different isoforms have been found for mecom.蛋白别名为：mecom; md
PRDM12 Polyclonal Antibody含PR域锌指蛋白12 多克隆抗体 (2017/1/22)
简介：prdm12 (pr domain 12) is a protein coding gene. diseases associated with prdm12 include neuropathy, hereditary sensory and autonomic, type viii. go annotations related to prdm12 include methyltransferase activity. an important paralog of prdm12 is prdm6.蛋白别名为：prdm12; pfm9; pr domain zinc finger protein 12; pr domain-containing protein 12;基因id为：59335；蛋白质id:q9h4q4
PRC Polyclonal Antibody过氧化物酶体增殖活化受体γ辅激活蛋白相关1 多克隆抗体 (2017/1/22)
简介：the peroxisome proliferator-activated receptor gamma, coactivator-related 1 encoded by pprc1is similar to ppar-gamma coactivator 1 (ppargc1/pgc-1), a protein that can activate mitochondrial biogenesis in part through a direct interaction with nuclear respiratory factor 1 (nrf1). this protein has been shown to interact with nrf1. it is thought to be a functional relative of ppar-gamma coactivator 1 that activates mitochondrial biogenesis through nrf1 in response to proliferative signals. alternat
PRAS40 Polyclonal Antibody蛋白激酶AKT底物1 多克隆抗体 (2017/1/22)
简介：akt1s1 is a proline-rich substrate of akt (mim 164730) that binds 14-3-3 protein (see ywhah, mim 113508) when phosphorylated 蛋白别名为：akt1s1; pras40; proline-rich akt1 substrate 1; 40 kda proline-rich akt substrate;基因id为：84335；蛋白质id:q96b36
PRAS40 (phospho Thr246) Polyclonal Antibody蛋白激酶AKT底物1 (phospho Thr246) 多克隆抗体 (2017/1/22)
简介：akt1s1 (akt1 substrate 1) is a protein coding gene. diseases associated with akt1s1 include?diaphragmatic eventration. among its related pathways are?ampk signaling pathway?and?longevity regulating pathway - multiple species.蛋白别名为：akt1s1; pras40; proline-rich akt1 substrate 1; 40 kda proline-rich akt substrate;基因id为：84335；蛋白质id:q96b36
PRAK Polyclonal Antibodyp38调节/激活蛋白激酶 多克隆抗体 (2017/1/22)
简介：the protein encoded by mapkapk5（mitogen-activated protein kinase-activated protein kinase 5） is a tumor suppressor and member of the serine/threonine kinase family. in response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by map kinases including mapk1/erk, mapk14/p38-alpha, and mapk11/p38-beta. the encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. this kinase phosphorylates hea
PRAK Polyclonal Antibodyp38调节/激活蛋白激酶 多克隆抗体 (2017/1/22)
简介：the protein encoded by mapkapk5（mitogen-activated protein kinase-activated protein kinase 5） is a tumor suppressor and member of the serine/threonine kinase family. in response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by map kinases including mapk1/erk, mapk14/p38-alpha, and mapk11/p38-beta. the encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. this kinase phosphorylates hea
PRAK (phospho Thr182) Polyclonal Antibodyp38调节/激活蛋白激酶 (phospho Thr182) 多克隆抗体 (2017/1/22)
简介：the protein encoded by mapkapk5（mitogen-activated protein kinase-activated protein kinase 5） is a tumor suppressor and member of the serine/threonine kinase family. in response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by map kinases including mapk1/erk, mapk14/p38-alpha, and mapk11/p38-beta. the encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. this kinase phosphorylates hea
Pragmin (phospho Tyr413) Polyclonal Antibody酪氨酸蛋白激酶SgK223 (phospho Tyr413) 多克隆抗体 (2017/1/22)
简介：sgk223 encodes an enzyme that belongs to the tyrosine protein kinase family. a similar protein in rat binds to rho family gtpase 2 (rnd2) and regulates neurite outgrowth via activation of ras homolog gene family, member a (rhoa). 蛋白别名为：sgk223; tyrosine-protein kinase sgk223; sugen kinase 223;基因id为：157285；蛋白质id:q86yv5
PRAF2 Polyclonal AntibodyPRA1域家族成员2 多克隆抗体 (2017/1/22)
简介：praf2 (pra1 domain family member 2) is a protein coding gene. diseases associated with praf2 include neuroblastoma. an important paralog of praf2 is arl6ip5.蛋白别名为：praf2; jm4; pra1 family protein 2;基因id为：11230；蛋白质id:o60831
PR48 Polyclonal Antibody蛋白磷酸酶2调控亚基3B 多克隆抗体 (2017/1/22)
简介：protein phosphatase 2 (formerly named type 2a) is one of the four major ser/thr phosphatases and is implicated in the negative control of cell growth and division. protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit a, a catalytic subunit c, and a regulatory subunit b. the regulatory subunit is encoded by a diverse set of genes that have been grouped into the b/pr55, b´/pr61, and b´´/pr72 families. these different regulatory subunits c
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