提供者：上海笃玛生物科技有限公司 发布时间：2024/9/14 13:57:04 阅读次数：2718次 进入该公司店铺
| Product Name | Gab1 Antibody (Y659) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
WB~~1:100~500 IHC~~1:10~50: | |
| Species Reactivity | Human |
| Concentration | 1 mg/ml |
| Purification |
| Alternative Names | More |
|---|---|
| Molecular Weight(MW) | 76616 Da |
| Function | Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) ａnd the insulin receptor (INSR) |
| Tissue Specificity | This Gab1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids surrounding Y659 of human GAB1. |
| Entrez Gene | 2549 |
|---|
Western blot analysis of Gab1 (arrow) using rabbit polyclonal Gab1 Antibody (Y659) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GAB1 gene (Lane 2) (Origene Technologies).
Formalin-fixed ａnd paraffin-embedded human breast carcinoma tissue reacted with Gab1 Antibody (Y659) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
| Application Notes | WB~~1:100~500 IHC~~1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot ａnd store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
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