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Phospho-Gab1-Y659 Antibody Catalog Number:OM217327

提供者:上海笃玛生物科技有限公司   发布时间:2024/9/14 13:43:21  阅读次数:2683次  进入该公司店铺

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Product Profile

Product NamePhospho-Gab1-Y659 Antibody
Antibody TypePrimary Antibodies

Key Feature

ClonalityPolyclonal
IsotypeIg
Host SpeciesRabbit
Tested Applications

DB

DB~~1:100~500:
Species Reactivity

Human

Concentration1 mg/ml
Purification

Target Information

Alternative Names
GAB1
GRB2-associated-binding protein 1
GRB2-associated binder 1
Growth factor receptor bound protein 2-associated protein 1
More
Molecular Weight(MW)76616 Da
Function
Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR)
Tissue SpecificityThis Phospho-Gab1-Y659 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 645~675 amino acids surrounding Y659 of human Gab1.

Database Links

Entrez Gene2549

Application

  • Application

    Dot blot analysis of Phospho-Gab1-Y659 polyclonal antibody (Cat. AP3302b) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration were 0.5ug per ml.

Application Notes
DB~~1:100~500:

Additional Information

FormLiquid
Storage InstructionsFor short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by protein A affinity chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with peptides. The antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

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