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PPM1A antibody Catalog Number:OM269349

提供者:上海笃玛生物科技有限公司   发布时间:2024/9/12 13:24:00  阅读次数:2673次  进入该公司店铺

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Product Profile

Product NamePPM1A antibody
Antibody TypePrimary Antibodies
Product description
Mouse monoclonal [p6c7] to PPM1APPM1A is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.
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Immunogen
Recombinant full length protein (Human).

Key Feature

ClonalityMonoclonal
IsotypeIgG2
Clone Numberp6c7
Host SpeciesMouse
Tested Applications

ELISAWB

ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity

HumanMouse

Concentration1 mg/ml
PurificationProtein G

Target Information

Gene Synonyms
EC 3.1.3.16 MGC9201 Mpp alpha Protein phosphatase 1A Protein phosphatase 1A magnesium dependent alpha
TargetPPM1A
Cellular LocalizationCylasmic
Light Chain Typekappa

Application

  • Application

    Western blot analysis of mouse liver cytosol extract using at a dilution of 1/250. Proteins were visualised using a goat anti-mouse secondary antibody conjugated to HRP and a DAB detection system.

Application Notes
ELISA: Use at an assay dependent dilution. WB: Use at a dilution of 1/250 - 1/1000. Predicted molecular weight: 42 kDa. Optimal dilutions/concentrations should be determined by the end user.:

Additional Information

FormLiquid
Storage InstructionsUpon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Storage BufferPreservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4

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