Ubrogepant

MCE 国际站：Ubrogepant

CAS：1374248-77-7

品牌：MedChemExpress (MCE)

存储条件：Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.

生物活性：Ubrogepant (MK-1602) 是一种新型口服降钙素基因相关肽受体 (CGRP) 拮抗剂，正在开发用于急性偏头痛的治疗
^[1]。 IC50 和目标：MK-1602
^[1]

热销产品：Olutasidenib | GR24 | 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 | HUHS015 | PEG6000 | Stearamide | Alpha-2-macroglobulin, Human (sf9, His) | Flavokawain A | Topiramate | Simethicone

研究领域：GPCR/G Protein | Neuronal Signaling

作用靶点：CGRP Receptor

热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物 | 寡核苷酸

Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides

参考文献：
[1]. Li CC, et al. Population PK Analyses of Ubrogepant (MK-1602), a CGRP Receptor Antagonist: Enriching In-Clinic Plasma PK Sampling With Outpatient Dried Blood Spot Sampling. J Clin Pharmacol. 2017 Nov 14. doi: 10.1002/jcph.1021.