欢迎来到 阿仪网

免费注册

首页|产品|求购|资讯|专题|找厂商|打听|品牌|资料|技术文献|展会|新品|促销|招标|优质仪器
广告

B Cell Receptor 信号通路图

提供者:上海睿之生物医药科技有限公司   发布时间:2012/6/18 11:53:11  阅读次数:6172次  进入该公司店铺

商家名片
赵**
请说明是阿仪网看到我的,谢谢!
  • 公司:上海睿之生物医药科技有限公司
  • 电话:02*******011
  • 手机:13******745
  • 微信:***
  • 交换名片后展示联系方式

交换名片

B cells produce immunoglobulins (Ig, antibodies) that specifically bind antigen molecules. B cells first produce a membrane-bound form of immunoglobulin, the B cell receptor, as part of B cell differentiation. Each B cell expresses one immunoglobulin but the population of B cells in each individual display a wide variety of antigen specificity, with each cell expressing Ig on its surface as part of the B cell receptor complex. When the B cell receptor binds to antigen, it initiates a signal through other proteins non-covalently associated with it in the B cell receptor complex, the Ig-alpha (CD79a) and Ig-beta (CD79b) chains. The signal initiated by binding of antigen to the B cell receptor complex causes growth and proliferation of the B cell and the creation of an amplified clone of effector cells that secrete the antigen-specific immunoglobulin. Activation of the B cell receptor by antigen also results in the production of memory cells that persist in circulation to produce a more rapid immune response after future challenges by the same antigen.

(来源:Scimall科学在线)

本信号转导涉及的信号分子主要包括:
BCR
,mlg,CD19,Ag,CRALChannel,Orai1,Lyn,Ezrin,Syk,SHP-1,SHP-2,SHIP,PTEN,Gab,BACP,Shc,Dok-3,PI3K,PIR-B,Csk,clathrin,Cbp/PAG,Cbl,p38,p70,p85,p110,CD19,CD22,CD40,CD45,Btk,Bam32,PLCγ2,LAB,BLNK,GRB2,SOS,RhoA,Akt,cdc42,Vav,HS1,Pyk2,Rsc,RapL,Riam,Rap,SOS,Rss,c-Raf,MEK1,MEK2,Erk1,Erk2,GRP,Dok-1,IP3R,STIM1,PKC,TAK1,CARMA1,Bcl10,MALT1,IKK,p38,IκB,NF-κB,CaM,GSK-3,mTOR,S6K,Calclneurln,NFAT,MEKK8,MKK3,MKK4,MKK6,MKK7,JNK1,JNK2,CaMK,MEF2C,CREB,ATF-2,Jun,Bcl-6,Egr-1,Elk-1,Bcl-xL,Bfl-1,Oct-2,Ets1,FoxO等。

点击图中信号分子,查看详细通路图及产品(抑制剂,抗体,磷酸化抗体,检测试剂盒,重组蛋白等)

B Cell Receptor 信号通路图

优质商品

X射线荧光光谱仪
X射线荧光光谱仪

版权声明

① 凡本网注明"来源:阿仪网"的所有作品,版权均属于阿仪网,未经本网授权不得转载、摘编或利 用其它方式使用。已获本网授 权的作品,应在授权范围内使用,并注明"来源:阿仪网"。违者本网将追究相关法律责任。

② 本信息由注册会员:上海睿之生物医药科技有限公司发布并且负责版权等法律责任。

旗下频道

色谱仪光谱仪反应釜试验箱试验机搅拌器培养箱离心机水分测定气体检测量热仪石油仪器纯水器比表面仪温度记录泵流量计万用表显微镜粒度仪测厚仪硬度计酸度计元素分析生物试剂电线电缆天平衡器传感器食品检测压力仪表电化学测厚仪阀门仪表电力仪表干燥设备药物检测