Recombinant Human PTH，Parathyroid Hormone ，PTH

产品说明(Description)

Recombinant Human Parathyroid Hormone is produced by our E.coli expression system ａnd the target gene encoding Ser32-Gln115 is expressed.

Accession #: P01270

Known as: Parathyroid Hormone; PTH; Parathormone; Parathyrin

制剂（Formulation）

Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.

质量控制（Quality Control）

Bioactivity* Measured by the UMR106 cell/cAMP method.

Specific Activity of 1.0 x 10^4 IU/mg.

Purity: Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin: Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.

复溶（Reconstitution）

Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg/ml.
Dissolve the lyophilized protein in distilled water
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

保存（Storage）

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

背景（Background）

Parathyroid hormone is the most important endocrine regulator of calcium ａnd phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands ａnd finds its major target cells in bone ａnd kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone ａnd has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.

电泳(SDS-PAGE)

参考文献(Reference)

1、Extraction ａnd purification of recombinant intact human Parathyroid Hormone (hPTH) from bacterial cell. Adnan E. Al-badran. et al. Journal of Biomedical Engineering ａnd Informatics. 2017.

FOR RESEARCH USE ONLY