依泽替米贝 依折麦布
英文名称 Ezetimibe 中文别名 依替米贝,伊折麦布,依泽替米贝
1-(4-氟苯基)-(3R)-[3-(4-氟苯基)-(3S)-羟基丙基]-(4S)-(4-羟基苯基)-2-丙内酰胺
英文名称:Ezetimibe,
1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)-azetidin-2-one 分子式:C24H21F2NO3 分子量:409.42CAS :163222-33-1
外观:白色结晶性粉末
含量:98%-102%
总杂:1.0%以下
单杂:0.3%以下分 子 式 C24H21F2NO3 分 子 量 409.43 作 用:依泽替米贝用于降胆固醇
依泽替米贝是一类新型的选择性胆固醇吸收抑制剂,通过与小肠刷状缘膜小囊泡上膜蛋白(相对分子质量145X103)结合,抑制小肠对饮食中和经胆汁输送到肠道中的胆固醇的吸收,降低血清和肝脏中的胆固醇含量。与胆酸鳌合剂不同,依泽替米贝不影响胆固醇酯、其他甾类(如牛黄胆酸)、三酰甘油和脂溶性维生素的吸收。其药理作用与乙酰辅酶A-胆固醇乙酰转移酶(ACAT)的抑制及LDL受体(清道夫受体)的表达与否无关。依泽替米贝被吸收后在肝脏中与葡萄糖醛酸结合后经肝肠循环,几乎特异地定位于小肠黏膜细胞。
供应依泽替米贝,生产依泽替米贝,依泽替米贝价格
我公司也供应依泽替米贝中间体:(4S)-3-[5-(4-氟苯基)-1,5-氧代戊基]-4-苯基-2-噁唑烷酮189028-93-1,4-[[(4-氟苯基)亚胺]甲基]-苯酚3382-63-6,
(3R,4S)-4-[4-(苄氧基)苯基]-1-(4-氟苯基)-3-[3-(4-氟苯基)-3-氧代丙基]氮杂环丁烷-2-酮 190595-65-4
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8-221,8-222,8-223,上泰电导率电极
Mobil Grease, United States
Mobilgrease XHP™ 220 greases are extended service lithium complex greases intended for a wide variety of applications and severe operating conditions. These greases were designed to outperform conventional products by applying cutting edge, proprietary, lithium complex manufacturing technology. They are formulated to provide excellent high temperature performance with superb adhesion, structural stability and resistance to water contamination. These greases have a high level of chemical stability and offer excellent protection against rust and corrosion. These greases feature high dropping points and maximum recommended operating temperature of 140º C (284°F). Mobilgrease XHP 220 greases are available in NLGI grades 00, 0, 1, 2 and 3 with an ISO VG 220 base oil viscosity.Mobilgrease XHP 220 greases are designed for a wide range of applications including the industrial, automotive, construction and marine sectors. Their performance features make them ideal choices for operating conditions including high temperature, water contamination, shock loading and extended re-lubrication operations. Mobilgrease XHP 222 Special is an extreme pressure grease fortified with 0.75% molybdenum disulfide that provides protection from wear under conditions pivoting and other conditions that lead to loss of oil film.
Features and Benefits
Mobilgrease XHP 220 greases are leading members of the Mobilgrease brand of products, which have gained a reputation for innovation and performance excellence. Mobilgrease XHP 220 greases are high performance products designed by our formulation technologists and backed by our world-wide technical support staff.A key factor in the excellent adhesion and cohesion properties and high drop point of Mobilgrease XHP 220 greases is the proprietary manufacturing technology developed at our research facilities and adopted by our modern manufacturing facilities. These products use specially selected additives to provide excellent oxidation stability, rust and corrosion control, resistance to water contamination as well as anti-wear and EP protection. Mobilgrease XHP 220 Series products offer the following features and potential benefits:
Features | Advantages and Potential Benefits |
Superb resistance to water washout and spray-off | Helps assure proper lubrication and protection even in the most severe water exposure conditions |
Highly adhesive and cohesive structure | Excellent grease tenacity,helps reduce leakage and extend re-lubrication intervals for reduced maintenance requirements |
Excellent rust and corrosion resistance | Protection of lubricated parts even in hostile aqueous environments |
Very good resistance to thermal, oxidative and structural degradation at high temperature | Helps extend grease life and enhance bearing protection in high temperature applicationshelping to reduce maintenance and replacement costs |
Very good anti-wear and EP performance | Reliable protection of lubricated equipment, even under conditions of high sliding with potential for extended equipment life and reduced unanticipated downtime |
Broad multi-purpose application | Provides potential for inventory rationalization and reduced inventory costs |
Applications
Mobilgrease XHP 220 greases are used in a wide range of equipment including industrial, automotive, construction and marine applications. Their blue color enables easy verification of application:Mobilgrease XHP 005 and 220 are softer, high-temperature greases recommended by ExxonMobil for centralized grease application systems, gear lubrication, and where extreme-cold-temperature pumpability is important.Mobilgrease XHP 221 is recommended by ExxonMobil for use in industrial and marine applications, chassis components and farm equipment. It provides excellent low temperature performance.Mobilgrease XHP 222 is recommended by ExxonMobil for industrial and marine applications, chassis components and farm equipment. Its sticky formulation stays in applications longer.Mobilgrease XHP 223 is recommended by ExxonMobil for applications where good high temperature and anti-leakage properties are required. It is particularly recommended for severe truck wheel bearing applications or for rolling element bearings subject to vibration, or where higher speeds require a grease with higher consistency to provide channeling characteristics.Mobilgrease XHP 222 Special contains 0.75% molybdenum disulfide, is grey in color and is recommended by ExxonMobil for moderate duty service in industrial applications, chassis components and farm equipment. It also finds application in king pins, U-joints, fifth wheels and bucket pins.
Specifications and Approvals
Mobilgrease XHP 220 Series meets or exceeds the requirements of | 005 | 220 | 221 | 222 | 223 | 222 Special |
DIN 51825: (2004-06) | KP1N-20 | KP2N-20 |
Mobilgrease XHP 220 Series has the following builder approvals: | 005 | 220 | 221 | 222 | 223 | 222 Special |
Fives Cincinnati | P-79 | P-72 | P-64 |
Typical Properties
Mobilgrease XHP | 005 | 220 | 221 | 222 | 223 | 222 Special |
NLGI Grade | 00 | 0 | 1 | 2 | 3 | 2 |
Thickener Type | Li-Complex | Li-Complex | Li-Complex | Li-Complex | Li-Complex | Li-Complex |
Color, Visual | Dark Blue | Dark Blue | Dark Blue | Dark Blue | Dark Blue | Grey-Black |
Molybdenum DiSulfide, wt% | -- | -- | -- | -- | -- | 0.75% |
Penetration, Worked, 25º C, ASTM D 217 | 415 | 370 | 325 | 280 | 235 | 280 |
Dropping Point, ºC, ASTM D 2265 | -- | 270 | 280 | 280 | 280 | 280 |
Viscosity of Oil, ASTM D 445 | ||||||
cSt @ 40º C | 220 | 220 | 220 | 220 | 220 | 220 |
4-Ball Wear Test, ASTM D 2266, scar, mm | 0.50 | 0.50 | 0.5 | 0.5 | 0.5 | 0.5 |
4-Ball Weld Load, ASTM D 2596, kg | 315 | 315 | 315 | 315 | 315 | 315 |
Timken OK Load, ASTM D 2509, lb | 40 | 40 | 40 | 40 | 40 | 40 |
Bomb Oxidation, ASTM D 942, Pressure drop at 100 hrs, kPa (psig) | 35 (5) | 35 (5) | 35 (5) | 35 (5) | 35 (5) | 35 (5) |
Corrosion Prevention, ASTM D 1743 | Pass | Pass | Pass | Pass | Pass | Pass |
Rust Protection, IP 220-mod., Distilled Water Washout | 0,0 | 0,0 | 0,0 | 0,0 | 0,0 | 0,0 |
Copper Strip Corrosion, ASTM D 4048 | 1B | 1B | 1B | 1B | 1B | 1B |
Penetration Consistency Change, Roll Stability, ASTM D 1831, mm/10 | -- | -15 | -15 | 0 | 0 | 0 |
型号 | JY-2220 MAESER | 名称 | 皮动态防水试验机 |
测试件数 | 4片 | 计数器 | LCD:0~999999×组 |
试片尺寸 | 4"×4"(114×114±2mm) | 天平精度 | 0.01g (自备) |
荷重 | 钢珠总量(135±5)g,ø3mm | 马力 | 90w |
测试位移 | (30±1)゚ | 体积 | 490×450×500mm |
速度 | 90±5 cpm | 重量 | 约55KG |
电源 | AC 220V ,5A | | |
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