Anti-ARC,ARC抗体

• Product nameAnti-Arc antibodySee all Arc primary antibodies ...
• Description
  Mouse polyclonal to Arc
• Tested applicationsWB more details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat, Cow, Chimpanzee, Rhesus monkey, Gorilla
• Immunogen

  Recombinant full length protein corresponding to amino acids 1-396 of Human Arc （NP_056008.1）

  Run BLAST with Run BLAST with
• Positive controlArc transfected 293T cell lysate

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term （1-2 weeks）. Aliquot ａnd store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Storage bufferpH: 7.20
  Constituent: 99% PBS
• Concentration50 µg at 1 mg/ml
  
• PurityProtein A purified
• ClonalityPolyclonal
• IsotypeIgG
• Research Areas
  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Alzheimer＇s disease
  • Other

  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • Ligand-Gated Ion Channels
  • AMPA / Kainate

  • Neuroscience
  • Neurotransmission
  • Intracellular Signaling
  • Regulation

Applications

Target

• FunctionRequired for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors （By similarity）. Plays a role in the regulation of cell morphology ａnd cytoskeletal organization. Required in the stress fiber dynamics ａnd cell migration.
• Sequence similaritiesBelongs to the ARC/ARG3.1 family.
• Cellular localizationCytoplasm > cytoskeleton. Endosome. Cytoplasmic vesicle > secretory vesicle > acrosome. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell projection > dendrite. Cell projection > dendritic spine. Cell junction > synapse. Associated with the cell cortex of neuronal soma ａnd dendrites. Enriched in postsynaptic density of dendritic spines. Associated with the sperm tail （By similarity）. Enriched on the plasma membrane.
• Information by UniProt
• Database links
  • Entrez Gene: 23237 Human
  • Entrez Gene: 11838 Mouse
  • Entrez Gene: 54323 Rat
  • Omim: 612461 Human
  • SwissProt: Q7LC44 Human
  • SwissProt: Q9WV31 Mouse
  • SwissProt: Q63053 Rat
  • Unigene: 40888 Human

  see all
• Alternative names
  • activity regulated cytoskeleton associated protein antibody
  • activity regulated gene 3.1 protein homolog antibody
  • Activity-regulated cytoskeleton-associated protein antibody

  see all

Anti-Arc antibody images

• 

  Western blot - Anti-Arc antibody （ab167305）
  All lanes : Anti-Arc antibody （ab167305） at 1 µg/ml
  
  Lane 1 : Arc transfected 293T cell lysate
  Lane 2 : Non-transfected 293T cell lysate
  
  Lysates/proteins at 15 µl per lane.
  
  
  Predicted band size : 45 kDa
  

References for Anti-Arc antibody （ab167305）