Anti-Acinus，腺泡Acinus抗体

• Product nameAnti-Acinus antibodySee all Acinus primary antibodies ...
• Description
  Rabbit polyclonal to Acinus
• SpecificityThe antibody recognises three different splice forms of Acinus, designated Acinus L, Acinus S ａnd Acinus S＇. The epitope is a region near the C-terminus of the cleaved active peptide p17.
• Tested applicationsICC/IF, WB, IHC-P more details
• Species reactivity
  Reacts with: Human
• Immunogen

  Synthetic peptide: TRTALHGVKWPQSNPK, corresponding to amino acids 1065-1080 of Human Acinus or 307 to 322 of human AcinusS, which are identical to those of mouse Acinus （2）. The selected antigenic sequence is locatednear the C-terminus of the cleaved active peptide p17.

  Run BLAST with Run BLAST with
• Positive controlK562 whole cell lysate.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot ａnd store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPBS with 0.02% sodium azide
• Concentration100 µg at 0.5 mg/ml
  
• PurityImmunogen affinity purified
• Purification notesPurified IgG was prepared from whole serum by affinity chromatography.
• ClonalityPolyclonal
• IsotypeIgG
• Research Areas
  • Cell Biology
  • Apoptosis
  • Nucleus
  • Chromatin Condensation

  • Epigenetics ａnd Nuclear Signaling
  • Cell cycle
  • Apoptosis
  • Nuclear

  • Cancer
  • Invasion/microenvironment
  • Apoptosis
  • Chromatin condensation

  • Metabolism
  • Pathways ａnd Processes
  • Metabolism processes
  • Apoptosis

Applications

Target

• FunctionComponent of a splicing-dependent multiprotein exon junction complex （EJC） deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins ａnd several more peripheral nuclear ａnd cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Induces apoptotic chromatin condensation after activation by CASP3.
• Tissue specificityUbiquitous.
• Sequence similaritiesContains 1 SAP domain.
• Post-translational
  modificationsUndergoes proteolytic cleavage; the processed form is active, contrary to the uncleaved form.
• Cellular localizationNucleus.
• Information by UniProt
• Database links
  • Entrez Gene: 22985 Human
  • Omim: 604562 Human
  • SwissProt: Q9UKV3 Human
  • Unigene: 124490 Human
• Alternative names
  • ACIN 1 antibody
  • ACIN1 antibody
  • ACINU_HUMAN antibody

  see all

Anti-Acinus antibody images

• 

  Immunocytochemistry/ Immunofluorescence - Acinus antibody （ab7352）

  ab7352 at 10µg/ml staining Acinus in K562 cells by ICC/IF

• 

  Western blot - Acinus antibody （ab7352）
  Anti-Acinus antibody （ab7352） at 1 µg/ml + K562 whole cell lysate
  
  Predicted band size : 151 kDa
  
• 

  Immunocytochemistry/ Immunofluorescence-Anti-Acinus antibody（ab7352）
  Immunofluorescence of Acinus in Hela cells using ab7352 at 10 ug/ml.
  
  

Protocols

• IHC-P protocol for ab7352

References for Anti-Acinus antibody （ab7352）