Anti-ABCG1， 三磷酸腺苷结合盒G1抗体

• Product nameAnti-ABCG1 [EP1366Y] antibodySee all ABCG1 primary antibodies ...
• Description
  Rabbit monoclonal [EP1366Y] to ABCG1
• Tested applicationsWB, IHC-P, ICC more details
• Species reactivity
  Reacts with: Rat, Cow, Human
  

  Does not react with

  Mouse
• Immunogen

  A synthetic peptide corresponding to residues on human ABCG1.

• Positive controlHUVEC cell lysate, human cervical carcinoma.
• General notesProduced under U.S. Patent No. 5,675,063.

Properties

• FormLiquid
• Storage instructionsShipped at 4°C. Upon delivery aliquot ａnd store at -20°C. Avoid freeze / thaw cycles.
• Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
• PurityTissue culture supernatant
• ClonalityMonoclonal
• Clone numberEP1366Y
• IsotypeIgG
• Research Areas
  • Neuroscience
  • Cell Type Marker
  • Glia marker
  • Astrocyte marker

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipid Metabolism
  • Cholesterol Metabolism

  • Cardiovascular
  • Lipids / Lipoproteins
  • Lipoproteins/Apolipoproteins

  • Signal Transduction
  • Metabolism
  • Lipid metabolism

  • Cardiovascular
  • Atherosclerosis
  • Lipoprotein metabolism

  • Cardiovascular
  • Atherosclerosis
  • Lipid transport

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of lipids ａnd lipoproteins

  • Metabolism
  • Pathways ａnd Processes
  • Metabolic signaling pathways
  • Lipid ａnd lipoprotein metabolism
  • Lipid metabolism

  • Metabolism
  • Pathways ａnd Processes
  • Metabolic signaling pathways
  • Lipid ａnd lipoprotein metabolism
  • Cholesterol Metabolism

  • Metabolism
  • Pathways ａnd Processes
  • Metabolic signaling pathways
  • Lipid ａnd lipoprotein metabolism
  • Lipoprotein metabolism

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Types of disease
  • Heart disease

Applications

• Application notesIs unsuitable for ,Flow Cyt or IP.

Target

• FunctionTransporter involved in macrophage lipid homeostasis. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.
• Tissue specificityExpressed in several tissues. Expressed in macrophages; expression is increased in macrophages from patients with Tangier disease.
• Sequence similaritiesBelongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer （TC 3.A.1.204） subfamily.
  Contains 1 ABC transmembrane type-2 domain.
  Contains 1 ABC transporter domain.
• Cellular localizationEndoplasmic reticulum membrane. Golgi apparatus membrane. Predominantly localized in the intracellular compartments mainly associated with the endoplasmic reticulum （ER） ａnd Golgi membranes.
• Information by UniProt
• Database links
  • Entrez Gene: 510745 Cow
  • Entrez Gene: 9619 Human
  • Entrez Gene: 85264 Rat
  • Omim: 603076 Human
  • SwissProt: P45844 Human
  • Unigene: 124649 Human
  • Unigene: 8398 Rat
• Alternative names
  • ABC transporter 8 antibody
  • Abc8 antibody
  • ABCG1 antibody

  see all

Anti-ABCG1 [EP1366Y] antibody images

• 

  Western blot - ABCG1 antibody [EP1366Y] （ab52617）
  Anti-ABCG1 [EP1366Y] antibody （ab52617） at 1/2000 dilution + HUVEC cell lysate at 10 µg
  
  Secondary
  Goat anti-rabbit HRP antiibody at 1/2000 dilution
  
  Predicted band size : 75 kDa
  Observed band size : 110 kDa （why is the actual band size different from the predicted?）
  
• 

  Immunohistochemistry （Paraffin-embedded sections） - ABCG1 antibody [EP1366Y] （ab52617）
  Ab52617 at 1/50 dilution staining human cervical carcinoma tissue; paraffin embedded.

References for Anti-ABCG1 [EP1366Y] antibody （ab52617）