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Recombinant Murine IL-4

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价格：￥电议

更新日期：2026/8/24 23:48:15

生产地：美洲

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简单介绍：Recombinant Murine IL-4
的IL-4，鼠重组
的关键调节体液免疫和适应性免疫

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详细内容

Alternate Names / Synonyms: Murine IL-4, IL-4, IL4, IL 4, m-IL-4, rm-IL-4, recombinant murine IL-4, recombinant IL-4, IL, interluekin

Gene Symbol: IL4

Accession #: P07750

Gene ID: 16189

Source: E. coli

Appearance: Lyophilized protein

Physical Form Description: Lyophilized with no additives.

Molecular Weight: 13.5 kDa

Purity by SDS-PAGE: ≥98%

Purity by HPLC: ≥98%

Endotoxin Level: <0.1 ng/μg

Biological Activity: The ED₅₀ determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells is <.2.0 ng/ml, corresponding to a specific activity of >5 x 10⁵ units/mg.

Reconstitution Instructions: Reconstitute in water to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers ａnd stored at 4°C for 1 week or –20°C for future use.

Storage Temp.: -20°C

Shipping: Gel pack

Background Information: IL-4 is a pleiotropic cytokine that regulates diverse T ａnd B cell responses including cell proliferation, survival ａnd gene expression. Produced by mast cells, T cells ａnd bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, ａnd IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 ａnd IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production ａnd allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 120 amino acid residues.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans.

的IL-4,鼠重组