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Anti-TREML2/TLT2髓系细胞触发受体样转录因子2抗体
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价格：￥电议
更新日期：2026/9/8 4:13:22
生 产 地：其它
产品型号：BY-2737R
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相关标签：TREML2/TLT2,髓系细胞触发受体样转录因子2抗体,TREML2/TLT2
详细内容
本公司经销TREML2/TLT2，髓系细胞触发受体样转录因子2抗体，克隆类型为polyclonal，宿主来源是Rabbit，TREML2/TLT2髓系细胞触发受体样转录因子2抗体可应用于WB、elisa、IP、IF、IHC等实验，欢迎垂询订购！
货号：BY-2737R
英文名称：Anti-TREML2/TLT2
中文名称：髓系细胞触发受体样转录因子2抗体
其他名称：名C6orf76; Chromosome 6 open reading frame 76; FLJ13693; MGC149715; MGC149716; TLT 2; TLT2; TREM like transcript 2; Trem like transcript 2 protein; Triggering receptor expressed on myeloid cells like 2; Triggering receptor expressed on myeloid cells like protein 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 33kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, dog, pig
产品介绍：TREML2 is expressed throughout B cell development in addition to being expressed on macrophages ａnd neutrophils ａnd is the only TREM molecule to be found on lymphocytes. TREML2 is expressed on B lineage cells early in development, ａnd the highest level of expression is detected on those mature peripheral B cell subpopulations that are involved in the initial humoral immune response against bacterial pathogens. TREML2 is unique in that it lacks either the conserved transmembrane lysine residue or ITAM/ITIMs within its own cytoplasmic domain. Thus, TREML2 does not exhibit any of the features associated with classical tyrosine-based signaling. Monocytes in the bone marrow or peripheral blood do not express detectable levels of TREML2, but its expression is up-regulated in conjunction with differentiation into macrophages. TREML2 is present on neutrophils in the bone marrow as well as the periphery, ａnd inflammatory stimuli result in a dramatic increase in the expression of TREML2 on these cells in vivo.TREML2 is a single-pass type I membrane protein, ａnd it contains 1 Ig-like V-type （immunoglobulin-like） domain. It is a cell surface receptor that may play a role in the innate ａnd adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable （IgV） domain activating receptors TREM1 ａnd TREM2, but it has distinct structural ａnd functional properties. Subunit : Interacts with CD276 ａnd this interaction enhances T-cell activation.Subcellular Location : Cell membrane; Single-pass type I membrane protein.Tissue Specificity : Detected in cultured B cells, T cell leukemia ａnd monocyte leukemia. Expressed constitutively on CD8 T-cells ａnd induced on CD4 T-cells after activation.Similarity : Contains 1 Ig-like V-type （immunoglobulin-like） domain.
货号：BY-2737R
英文名称：Anti-TREML2/TLT2
中文名称：髓系细胞触发受体样转录因子2抗体
其他名称：名C6orf76; Chromosome 6 open reading frame 76; FLJ13693; MGC149715; MGC149716; TLT 2; TLT2; TREM like transcript 2; Trem like transcript 2 protein; Triggering receptor expressed on myeloid cells like 2; Triggering receptor expressed on myeloid cells like protein 2.
抗体来源：Rabbit
克隆类型：polyclonal
蛋白分子量：predicted molecular weight: 33kDa
纯化方法：affinity purified by Protein A
交叉反应：hu, mo, rat, cow, dog, pig
产品介绍：TREML2 is expressed throughout B cell development in addition to being expressed on macrophages ａnd neutrophils ａnd is the only TREM molecule to be found on lymphocytes. TREML2 is expressed on B lineage cells early in development, ａnd the highest level of expression is detected on those mature peripheral B cell subpopulations that are involved in the initial humoral immune response against bacterial pathogens. TREML2 is unique in that it lacks either the conserved transmembrane lysine residue or ITAM/ITIMs within its own cytoplasmic domain. Thus, TREML2 does not exhibit any of the features associated with classical tyrosine-based signaling. Monocytes in the bone marrow or peripheral blood do not express detectable levels of TREML2, but its expression is up-regulated in conjunction with differentiation into macrophages. TREML2 is present on neutrophils in the bone marrow as well as the periphery, ａnd inflammatory stimuli result in a dramatic increase in the expression of TREML2 on these cells in vivo.TREML2 is a single-pass type I membrane protein, ａnd it contains 1 Ig-like V-type （immunoglobulin-like） domain. It is a cell surface receptor that may play a role in the innate ａnd adaptive immune response. TREML2 is located in a gene cluster on chromosome 6 with the single Ig variable （IgV） domain activating receptors TREM1 ａnd TREM2, but it has distinct structural ａnd functional properties. Subunit : Interacts with CD276 ａnd this interaction enhances T-cell activation.Subcellular Location : Cell membrane; Single-pass type I membrane protein.Tissue Specificity : Detected in cultured B cells, T cell leukemia ａnd monocyte leukemia. Expressed constitutively on CD8 T-cells ａnd induced on CD4 T-cells after activation.Similarity : Contains 1 Ig-like V-type （immunoglobulin-like） domain.
TREML2/TLT2,髓系细胞触发受体样转录因子2抗体,TREML2/TLT2
