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Anti-TBRG1转化生长因子β调节蛋白1抗体

Anti-TBRG1转化生长因子β调节蛋白1抗体

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更新日期:2026/9/8 4:13:22

生 产 地:其它

产品型号:BY-4268R

简单介绍:本公司经销TBRG1,转化生长因子β调节蛋白1抗体,克隆类型为polyclonal,宿主来源是Rabbit,TBRG1转化生长因子β调节蛋白1抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

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相关标签:TBRG1,转化生长因子β调节蛋白1抗体,TBRG1转化生长因子β调节蛋白1抗体

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本公司经销TBRG1,转化生长因子β调节蛋白1抗体,克隆类型为polyclonal,宿主来源是Rabbit,TBRG1转化生长因子β调节蛋白1抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

货号:BY-4268R
英文名称:Anti-TBRG1
中文名称:转化生长因子β调节蛋白1抗体
其他名称:名NIAM; Nuclear interactor of ARF and Mdm2; Transforming growth factor beta regulator 1; TBRG1; TBRG-1; TBRG 1; Transforming growth factor beta regulator 1.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 45kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, pig, hrs, dog, cow, Rb
产品介绍:Acts as a growth inhibitor. Can activate TP53/p53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. There are two isoforms.Function : Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability.Subunit : Interacts with CDKN2A and MDM2.Subcellular Location : Nucleus.Tissue Specificity : Widely expressed at low levels in most tissues, with highest levels in pancreas, lung and liver. Expression is decreased in primary tumors including lung, liver, breast, pancreas and kidney carcinomas, chronic lymphocytic leukemia and diffuse large B-cell lymphoma.Post-translational modifications : Ubiquitinated; mediated by MDM2 and leading to its subsequent proteasomal degradation.Similarity : Belongs to the TBRG1 family.Contains 1 FYR C-terminal domain.Contains 1 FYR N-terminal domain.
TBRG1,转化生长因子β调节蛋白1抗体,TBRG1转化生长因子β调节蛋白1抗体

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