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Anti-TLR9/CD289Toll样受体9抗体

Anti-TLR9/CD289Toll样受体9抗体

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价格:¥电议

更新日期:2026/9/8 4:13:22

生 产 地:其它

产品型号:BY-2717R

简单介绍:本公司经销TLR9/CD289,Toll样受体9抗体,克隆类型为polyclonal,宿主来源是Rabbit,TLR9/CD289Toll样受体9抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

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相关标签:TLR9/CD289,Toll样受体9抗体,TLR9/CD289Toll样受体9

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本公司经销TLR9/CD289,Toll样受体9抗体,克隆类型为polyclonal,宿主来源是Rabbit,TLR9/CD289Toll样受体9抗体可应用于WB、elisa、IP、IF、IHC等实验,欢迎垂询订购!

货号:BY-2717R
英文名称:Anti-TLR9/CD289
中文名称:Toll样受体9抗体
其他名称:名Toll-like receptor 9; CD 289; CD289; TLR 9; Toll like receptor 9; Toll like receptor 9 isoform A precursor; Toll like receptor 9 isoform B.
抗体来源:Rabbit
克隆类型:polyclonal
蛋白分子量:predicted molecular weight: 111kDa
纯化方法:affinity purified by Protein A
交叉反应:hu, mo, rat, cow, hrs, shp, pig, dog
产品介绍:TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.Subunit : Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with CNPY3 (By similarity). Interacts (via transmembrane domain) with UNC93B1 (By similarity). Interacts with BTK.Subcellular Location : Endoplasmic reticulum membrane; Single-pass type I membrane protein (By similarity). Endosome (By similarity). Lysosome (By similarity). Cytoplasmic vesicle, phagosome (By similarity). Note=Relocalizes from endoplasmic reticulum to endosome and lysosome upon stimulation with agonist (By similarity).Tissue Specificity : Highly expressed in spleen, lymph node, tonsil and peripheral blood leukocytes, especially in plasmacytoid pre-dendritic cells. Levels are much lower in monocytes and CD11c+ immature dendritic cells. Also detected in lung and liver.Similarity : Belongs to the Toll-like receptor family. Contains 26 LRR (leucine-rich) repeats. Contains 1 TIR domain.Toll样受体-9(Toll-like receptor 9,TLR9)是哺乳动物TLRs家族中一员,作为细胞表面的天然模式识别受体,主要参与免疫刺激序列(CpG序列)激活免疫细胞的信号传导,从而在天然抗感染免疫及联系天然免疫和获得性免疫中发挥重要作用。
TLR9/CD289,Toll样受体9抗体,TLR9/CD289Toll样受体9

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